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Artigo de periodico
Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation (2024)
Nascimento, Mariane Cristina do ; Pereira-Martins, Diego Antonio ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Hematology, Transfusion and Cell Therapy. Unidades: FM, ICB
Subjects: FARMACOLOGIA, MEDULA ÓSSEA, LEUCEMIA MIELOIDE AGUDA, CÉLULAS-TRONCO, PROLIFERAÇÃO CELULAR, EXPRESSÃO GÊNICA, SEQUENCIAMENTO GENÉTICO, MITOCÔNDRIAS, ESTRESSE OXIDATIVO, METABOLISMO CELULAR
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ABNT
NASCIMENTO, Mariane Cristina do et al. Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation. Hematology, Transfusion and Cell Therapy, v. 46, n. Suppl. 6, p. S48-S52, 2024Tradução . . Disponível em: https://doi.org/10.1016/j.htct.2023.10.007. Acesso em: 08 out. 2025.
APA
Nascimento, M. C. do, Pereira-Martins, D. A., Rego, E. M., & Machado Neto, J. A. (2024). Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation. Hematology, Transfusion and Cell Therapy, 46( Suppl. 6), S48-S52. doi:10.1016/j.htct.2023.10.007
NLM
Nascimento MC do, Pereira-Martins DA, Rego EM, Machado Neto JA. Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation [Internet]. Hematology, Transfusion and Cell Therapy. 2024 ; 46( Suppl. 6): S48-S52.[citado 2025 out. 08 ] Available from: https://doi.org/10.1016/j.htct.2023.10.007
Vancouver
Nascimento MC do, Pereira-Martins DA, Rego EM, Machado Neto JA. Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation [Internet]. Hematology, Transfusion and Cell Therapy. 2024 ; 46( Suppl. 6): S48-S52.[citado 2025 out. 08 ] Available from: https://doi.org/10.1016/j.htct.2023.10.007
Artigo de periodico
All-trans retinoic acid potentiates cell death induced by quizartinib in acute myeloid leukemia with FLT3-ITD mutations (2024)
Sánchez-Mendoza, Silvia Elena; Deus-Wagatsuma, Virginia Mara de; Nascimento, Mariane Cristina do; Lima, Keli ; Machado Neto, João Agostinho ; Djavaheri-Mergny, Mojgan; Rego, Eduardo Magalhães
Source: Annals of Hematology. Unidades: ICB, FM
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, APOPTOSE, QUIMIOTERAPIA COMBINADA, PROTEÍNAS QUINASES, ANTINEOPLÁSICOS, MUTAÇÃO GENÉTICA
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SÁNCHEZ-MENDOZA, Silvia Elena et al. All-trans retinoic acid potentiates cell death induced by quizartinib in acute myeloid leukemia with FLT3-ITD mutations. Annals of Hematology, v. 103, p. 5405-5416, 2024Tradução . . Disponível em: https://doi.org/10.1007/s00277-024-06089-w. Acesso em: 08 out. 2025.
APA
Sánchez-Mendoza, S. E., Deus-Wagatsuma, V. M. de, Nascimento, M. C. do, Lima, K., Machado Neto, J. A., Djavaheri-Mergny, M., & Rego, E. M. (2024). All-trans retinoic acid potentiates cell death induced by quizartinib in acute myeloid leukemia with FLT3-ITD mutations. Annals of Hematology, 103, 5405-5416. doi:10.1007/s00277-024-06089-w
NLM
Sánchez-Mendoza SE, Deus-Wagatsuma VM de, Nascimento MC do, Lima K, Machado Neto JA, Djavaheri-Mergny M, Rego EM. All-trans retinoic acid potentiates cell death induced by quizartinib in acute myeloid leukemia with FLT3-ITD mutations [Internet]. Annals of Hematology. 2024 ; 103 5405-5416.[citado 2025 out. 08 ] Available from: https://doi.org/10.1007/s00277-024-06089-w
Vancouver
Sánchez-Mendoza SE, Deus-Wagatsuma VM de, Nascimento MC do, Lima K, Machado Neto JA, Djavaheri-Mergny M, Rego EM. All-trans retinoic acid potentiates cell death induced by quizartinib in acute myeloid leukemia with FLT3-ITD mutations [Internet]. Annals of Hematology. 2024 ; 103 5405-5416.[citado 2025 out. 08 ] Available from: https://doi.org/10.1007/s00277-024-06089-w
Artigo de periodico
Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia (2023)
Lima, Keli ; Carvalho, Maria Fernanda Lopes ; Martins, Diego Antonio Pereira ; Silva, Wellington Fernandes da; Nascimento, Mariane Cristina do ; Miranda, Lívia Bassani Lins De ; Medeiros, Rita de Cássia Cavaglieri ; Nardinelli, Luciana; Leal, Aline de Medeiros; Velloso, Elvira Deolinda Rodrigues Pereira ; Bendit, Israel ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: FM, ICB, FMRP
Subjects: HEMATOLOGIA, LEUCEMIA, LINFOMA, DOENÇAS SANGUÍNEAS E LINFÁTICAS, INIBIDORES QUÍMICOS, ESTUDOS DE COORTES, EXPRESSÃO GÊNICA, REAÇÃO EM CADEIA POR POLIMERASE, WESTERN BLOTTING, CITOMETRIA DE FLUXO, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS
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ABNT
LIMA, Keli et al. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia. Blood, v. 142, p. 5886, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-189786. Acesso em: 08 out. 2025.
APA
Lima, K., Carvalho, M. F. L., Martins, D. A. P., Silva, W. F. da, Nascimento, M. C. do, Miranda, L. B. L. D., et al. (2023). Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia. Blood, 142, 5886. doi:10.1182/blood-2023-189786
NLM
Lima K, Carvalho MFL, Martins DAP, Silva WF da, Nascimento MC do, Miranda LBLD, Medeiros R de CC, Nardinelli L, Leal A de M, Velloso EDRP, Bendit I, Schuringa JJ, Rego EM, Machado Neto JA. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia [Internet]. Blood. 2023 ; 142 5886.[citado 2025 out. 08 ] Available from: https://doi.org/10.1182/blood-2023-189786
Vancouver
Lima K, Carvalho MFL, Martins DAP, Silva WF da, Nascimento MC do, Miranda LBLD, Medeiros R de CC, Nardinelli L, Leal A de M, Velloso EDRP, Bendit I, Schuringa JJ, Rego EM, Machado Neto JA. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia [Internet]. Blood. 2023 ; 142 5886.[citado 2025 out. 08 ] Available from: https://doi.org/10.1182/blood-2023-189786
Artigo de periodico
The multikinase inhibitor AD80 induces mitotic catastrophe and autophagy in pancreatic cancer cells (2023)
Lima, Keli ; Miranda, Lívia Bassani Lins De ; Garnique, Anali Del Milagro Bernabe ; Almeida, Bruna Oliveira de ; Nascimento, Mariane Cristina do; Alcântara, Guilherme Augusto Sousa; Machado-Santelli, Glaucia Maria ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Cancers. Unidades: ICB, FM
Subjects: BIOLOGIA CELULAR, FARMACOLOGIA, CÉLULAS CULTIVADAS DE TUMOR, NEOPLASIAS PANCREÁTICAS, INIBIDORES DE ENZIMAS, ANTINEOPLÁSICOS, DANO AO DNA, APOPTOSE
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ABNT
LIMA, Keli et al. The multikinase inhibitor AD80 induces mitotic catastrophe and autophagy in pancreatic cancer cells. Cancers, v. 15, n. 15, p. 14 , 2023Tradução . . Disponível em: https://doi.org/10.3390/cancers15153866. Acesso em: 08 out. 2025.
APA
Lima, K., Miranda, L. B. L. D., Garnique, A. D. M. B., Almeida, B. O. de, Nascimento, M. C. do, Alcântara, G. A. S., et al. (2023). The multikinase inhibitor AD80 induces mitotic catastrophe and autophagy in pancreatic cancer cells. Cancers, 15( 15), 14 . doi:10.3390/cancers15153866
NLM
Lima K, Miranda LBLD, Garnique ADMB, Almeida BO de, Nascimento MC do, Alcântara GAS, Machado-Santelli GM, Rego EM, Machado Neto JA. The multikinase inhibitor AD80 induces mitotic catastrophe and autophagy in pancreatic cancer cells [Internet]. Cancers. 2023 ; 15( 15): 14 .[citado 2025 out. 08 ] Available from: https://doi.org/10.3390/cancers15153866
Vancouver
Lima K, Miranda LBLD, Garnique ADMB, Almeida BO de, Nascimento MC do, Alcântara GAS, Machado-Santelli GM, Rego EM, Machado Neto JA. The multikinase inhibitor AD80 induces mitotic catastrophe and autophagy in pancreatic cancer cells [Internet]. Cancers. 2023 ; 15( 15): 14 .[citado 2025 out. 08 ] Available from: https://doi.org/10.3390/cancers15153866
Artigo de periodico
Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia (2023)
Lima, Keli ; Carvalho, Maria Fernanda Lopes ; Martins, Diego Antonio Pereira ; Nascimento, Mariane Cristina do ; Nogueira, Frederico Lisboa ; Medeiros, Rita de Cássia Cavaglieri ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: FM, ICB, FMRP
Subjects: FARMACOLOGIA, HEMATOLOGIA, LEUCEMIA MIELOIDE AGUDA, QUIMIOTERAPIA COMBINADA, CÉLULAS CULTIVADAS DE TUMOR, PROLIFERAÇÃO CELULAR, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS, PROTEÍNAS, CÉLULAS MIELOIDES
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ABNT
LIMA, Keli et al. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia. Blood, v. 142, n. Supl. 1, p. 5774, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-189998. Acesso em: 08 out. 2025.
APA
Lima, K., Carvalho, M. F. L., Martins, D. A. P., Nascimento, M. C. do, Nogueira, F. L., Medeiros, R. de C. C., et al. (2023). Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia. Blood, 142( Supl. 1), 5774. doi:10.1182/blood-2023-189998
NLM
Lima K, Carvalho MFL, Martins DAP, Nascimento MC do, Nogueira FL, Medeiros R de CC, Schuringa JJ, Rego EM, Machado Neto JA. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia [Internet]. Blood. 2023 ; 142( Supl. 1): 5774.[citado 2025 out. 08 ] Available from: https://doi.org/10.1182/blood-2023-189998
Vancouver
Lima K, Carvalho MFL, Martins DAP, Nascimento MC do, Nogueira FL, Medeiros R de CC, Schuringa JJ, Rego EM, Machado Neto JA. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia [Internet]. Blood. 2023 ; 142( Supl. 1): 5774.[citado 2025 out. 08 ] Available from: https://doi.org/10.1182/blood-2023-189998
Trabalho de evento-resumo periodico
AD80 inhibits aurora kinases and induces mitotic catastrophe and autophagy in pancreatic cancer cells (2023)
Lima, Keli ; Miranda, Lívia Bassani Lins de ; Garnique, Anali Del Milagro Bernabe ; Almeida, Bruna Oliveira de ; Nascimento, Mariane Cristina do; Machado-Santelli, Glaucia Maria ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Molecular Biology of the cell. Conference titles: Annual Meeting of the American Society for Cell Biology (ASCB) and the European Molecular Biology Organization (EMBO). Unidades: ICB, FM
Subjects: FARMACOLOGIA, CÉLULAS CULTIVADAS DE TUMOR, ILHOTAS DE LANGERHANS, ANTINEOPLÁSICOS, NEOPLASIAS PANCREÁTICAS, CITOMETRIA DE FLUXO, MICROSCOPIA DE FLUORESCÊNCIA, WESTERN BLOTTING
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LIMA, Keli et al. AD80 inhibits aurora kinases and induces mitotic catastrophe and autophagy in pancreatic cancer cells. Molecular Biology of the cell. Bethesda, MD: Instituto de Ciências Biomédicas, Universidade de São Paulo. Disponível em: https://doi.org/10.1091/mbc.E22-12-0555. Acesso em: 08 out. 2025. , 2023
APA
Lima, K., Miranda, L. B. L. de, Garnique, A. D. M. B., Almeida, B. O. de, Nascimento, M. C. do, Machado-Santelli, G. M., et al. (2023). AD80 inhibits aurora kinases and induces mitotic catastrophe and autophagy in pancreatic cancer cells. Molecular Biology of the cell. Bethesda, MD: Instituto de Ciências Biomédicas, Universidade de São Paulo. doi:10.1091/mbc.E22-12-0555
NLM
Lima K, Miranda LBL de, Garnique ADMB, Almeida BO de, Nascimento MC do, Machado-Santelli GM, Rego EM, Machado Neto JA. AD80 inhibits aurora kinases and induces mitotic catastrophe and autophagy in pancreatic cancer cells [Internet]. Molecular Biology of the cell. 2023 ; 34( 2): 167-168.[citado 2025 out. 08 ] Available from: https://doi.org/10.1091/mbc.E22-12-0555
Vancouver
Lima K, Miranda LBL de, Garnique ADMB, Almeida BO de, Nascimento MC do, Machado-Santelli GM, Rego EM, Machado Neto JA. AD80 inhibits aurora kinases and induces mitotic catastrophe and autophagy in pancreatic cancer cells [Internet]. Molecular Biology of the cell. 2023 ; 34( 2): 167-168.[citado 2025 out. 08 ] Available from: https://doi.org/10.1091/mbc.E22-12-0555
Artigo de periodico
Pharmacological inhibition of PIP4K2 potentiates venetoclax-induced apoptosis in Acute Myeloid Leukemia (2023)
Lima, Keli ; Carvalho, Maria Fernanda Lopes ; Pereira-Martins, Diego Antonio ; Nogueira, Frederico Lisboa ; Miranda, Lívia Bassani Lins de ; Mariane Cristina do Nascimento ; Cavaglieri, Rita de Cássia ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: International Journal of Molecular Sciences. Unidades: FM, ICB, FMRP
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS, APOPTOSE, PROTEÍNAS PROTO-ONCOGÊNICAS, COMPOSTOS HETEROCÍCLICOS
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ABNT
LIMA, Keli et al. Pharmacological inhibition of PIP4K2 potentiates venetoclax-induced apoptosis in Acute Myeloid Leukemia. International Journal of Molecular Sciences, v. 24, n. 23, p. 12 , 2023Tradução . . Disponível em: https://doi.org/10.3390/ijms242316899. Acesso em: 08 out. 2025.
APA
Lima, K., Carvalho, M. F. L., Pereira-Martins, D. A., Nogueira, F. L., Miranda, L. B. L. de, Mariane Cristina do Nascimento,, et al. (2023). Pharmacological inhibition of PIP4K2 potentiates venetoclax-induced apoptosis in Acute Myeloid Leukemia. International Journal of Molecular Sciences, 24( 23), 12 . doi:10.3390/ijms242316899
NLM
Lima K, Carvalho MFL, Pereira-Martins DA, Nogueira FL, Miranda LBL de, Mariane Cristina do Nascimento, Cavaglieri R de C, Schuringa JJ, Rego EM, Machado Neto JA. Pharmacological inhibition of PIP4K2 potentiates venetoclax-induced apoptosis in Acute Myeloid Leukemia [Internet]. International Journal of Molecular Sciences. 2023 ; 24( 23): 12 .[citado 2025 out. 08 ] Available from: https://doi.org/10.3390/ijms242316899
Vancouver
Lima K, Carvalho MFL, Pereira-Martins DA, Nogueira FL, Miranda LBL de, Mariane Cristina do Nascimento, Cavaglieri R de C, Schuringa JJ, Rego EM, Machado Neto JA. Pharmacological inhibition of PIP4K2 potentiates venetoclax-induced apoptosis in Acute Myeloid Leukemia [Internet]. International Journal of Molecular Sciences. 2023 ; 24( 23): 12 .[citado 2025 out. 08 ] Available from: https://doi.org/10.3390/ijms242316899
Artigo de periodico-carta/editorial
Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs (2023)
Machado Neto, João Agostinho ; Nascimento, Mariane Cristina do ; Garnique, Anali Del Milagro Bernabe ; Lima, Keli
Source: Translational Cancer Research. Unidades: ICB, FM
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, BIOMARCADORES, DOENÇAS SANGUÍNEAS E LINFÁTICAS
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ABNT
MACHADO NETO, João Agostinho et al. Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs. Translational Cancer Research. Shatin: AME Publishing Company. Disponível em: https://dx.doi.org/10.21037/tcr-23-993. Acesso em: 08 out. 2025. , 2023
APA
Machado Neto, J. A., Nascimento, M. C. do, Garnique, A. D. M. B., & Lima, K. (2023). Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs. Translational Cancer Research. Shatin: AME Publishing Company. doi:10.21037/tcr-23-993
NLM
Machado Neto JA, Nascimento MC do, Garnique ADMB, Lima K. Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs [Internet]. Translational Cancer Research. 2023 ; 12( 9): 2235-2238.[citado 2025 out. 08 ] Available from: https://dx.doi.org/10.21037/tcr-23-993
Vancouver
Machado Neto JA, Nascimento MC do, Garnique ADMB, Lima K. Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs [Internet]. Translational Cancer Research. 2023 ; 12( 9): 2235-2238.[citado 2025 out. 08 ] Available from: https://dx.doi.org/10.21037/tcr-23-993

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