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Artigo de periodico
Novel highlight in malarial drug discovery: aspartate transcarbamoylase (2022)
Wang, Chao; Krüger, Arne ; Du, Xiaochen; Wrenger, Carsten ; Groves, Matthew R.
Source: Frontiers in Cellular and Infection Microbiology. Unidade: ICB
Subjects: PARASITOLOGIA, ASPARTATO CARBAMOILTRANSFERASE, ANTIMALÁRICOS, MALÁRIA, COMPOSTOS ORGÂNICOS, PLASMODIUM FALCIPARUM, AMINOÁCIDOS, CRISTALOGRAFIA DE RAIOS X
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ABNT
WANG, Chao et al. Novel highlight in malarial drug discovery: aspartate transcarbamoylase. Frontiers in Cellular and Infection Microbiology, v. 12, p. 1-9, 2022Tradução . . Disponível em: https://doi.org/10.3389/fcimb.2022.841833. Acesso em: 07 nov. 2024.
APA
Wang, C., Krüger, A., Du, X., Wrenger, C., & Groves, M. R. (2022). Novel highlight in malarial drug discovery: aspartate transcarbamoylase. Frontiers in Cellular and Infection Microbiology, 12, 1-9. doi:10.3389/fcimb.2022.841833
NLM
Wang C, Krüger A, Du X, Wrenger C, Groves MR. Novel highlight in malarial drug discovery: aspartate transcarbamoylase [Internet]. Frontiers in Cellular and Infection Microbiology. 2022 ; 12 1-9.[citado 2024 nov. 07 ] Available from: https://doi.org/10.3389/fcimb.2022.841833
Vancouver
Wang C, Krüger A, Du X, Wrenger C, Groves MR. Novel highlight in malarial drug discovery: aspartate transcarbamoylase [Internet]. Frontiers in Cellular and Infection Microbiology. 2022 ; 12 1-9.[citado 2024 nov. 07 ] Available from: https://doi.org/10.3389/fcimb.2022.841833
Artigo de periodico
Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials (2022)
Wang, Chao ; Zhang, Bidong ; Krüger, Arne ; Du, Xiaochen; Visser, Lidia; Dömling, Alexander S. S. ; Wrenger, Carsten ; Groves, Matthew R.
Source: Journal of American Chemical Society. Unidade: ICB
Subjects: PARASITOLOGIA, ANTIMALÁRICOS, PLASMODIUM MALARIAE, PLASMODIUM FALCIPARUM, CATALASE, ATIVAÇÃO ENZIMÁTICA, AMINOÁCIDOS
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WANG, Chao et al. Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials. Journal of American Chemical Society, p. 1-8, 2022Tradução . . Disponível em: https://doi.org/10.1021/jacs.2c08128. Acesso em: 07 nov. 2024.
APA
Wang, C., Zhang, B., Krüger, A., Du, X., Visser, L., Dömling, A. S. S., et al. (2022). Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials. Journal of American Chemical Society, 1-8. doi:10.1021/jacs.2c08128
NLM
Wang C, Zhang B, Krüger A, Du X, Visser L, Dömling ASS, Wrenger C, Groves MR. Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials [Internet]. Journal of American Chemical Society. 2022 ; 1-8.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1021/jacs.2c08128
Vancouver
Wang C, Zhang B, Krüger A, Du X, Visser L, Dömling ASS, Wrenger C, Groves MR. Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials [Internet]. Journal of American Chemical Society. 2022 ; 1-8.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1021/jacs.2c08128
Artigo de periodico
Lipoic acid metabolism as a potential chemotherapeutic target against Plasmodium falciparum and Staphylococcus aureus (2021)
Yan, Sun Liu Rei ; Wakasuqui, Felipe ; Du, Xiaochen; Groves, Matthew R. ; Wrenger, Carsten
Source: Frontiers in Chemistry. Unidade: ICB
Subjects: PARASITOLOGIA, COMPOSTOS ORGÂNICOS, METABOLISMO CELULAR, LIPÍDEOS, ÁCIDOS GRAXOS, LIPOPROTEÍNAS, PLASMODIUM, STAPHYLOCOCCUS, CARBOIDRATOS
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YAN, Sun Liu Rei et al. Lipoic acid metabolism as a potential chemotherapeutic target against Plasmodium falciparum and Staphylococcus aureus. Frontiers in Chemistry, v. 9, p. 1-7, 2021Tradução . . Disponível em: https://doi.org/10.3389/fchem.2021.742175. Acesso em: 07 nov. 2024.
APA
Yan, S. L. R., Wakasuqui, F., Du, X., Groves, M. R., & Wrenger, C. (2021). Lipoic acid metabolism as a potential chemotherapeutic target against Plasmodium falciparum and Staphylococcus aureus. Frontiers in Chemistry, 9, 1-7. doi:10.3389/fchem.2021.742175
NLM
Yan SLR, Wakasuqui F, Du X, Groves MR, Wrenger C. Lipoic acid metabolism as a potential chemotherapeutic target against Plasmodium falciparum and Staphylococcus aureus [Internet]. Frontiers in Chemistry. 2021 ; 9 1-7.[citado 2024 nov. 07 ] Available from: https://doi.org/10.3389/fchem.2021.742175
Vancouver
Yan SLR, Wakasuqui F, Du X, Groves MR, Wrenger C. Lipoic acid metabolism as a potential chemotherapeutic target against Plasmodium falciparum and Staphylococcus aureus [Internet]. Frontiers in Chemistry. 2021 ; 9 1-7.[citado 2024 nov. 07 ] Available from: https://doi.org/10.3389/fchem.2021.742175
Artigo de periodico
New directions in antimalarial target validation (2020)
Batista, Fernando de Assis ; Gyau, Benjamin; Santos, Juliana Fátima Vilachã Madeira Rodrigues dos ; Bosch, Soraya Soraya ; Lunev, Sergey ; Wrenger, Carsten ; Groves, Matthew R.
Source: Expert Opinion on Drug Discovery. Unidade: ICB
Subjects: PARASITOLOGIA, MALÁRIA, ANTIMALÁRICOS, PLASMA DE ANIMAL, AMINOÁCIDOS, PLASMODIUM FALCIPARUM, MAPEAMENTO GENÉTICO, POLIPEPTÍDEOS
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BATISTA, Fernando de Assis et al. New directions in antimalarial target validation. Expert Opinion on Drug Discovery, v. 15, n. 2, p. 189–202, 2020Tradução . . Disponível em: https://doi.org/10.1080/17460441.2020.1691996. Acesso em: 07 nov. 2024.
APA
Batista, F. de A., Gyau, B., Santos, J. F. V. M. R. dos, Bosch, S. S., Lunev, S., Wrenger, C., & Groves, M. R. (2020). New directions in antimalarial target validation. Expert Opinion on Drug Discovery, 15( 2), 189–202. doi:10.1080/17460441.2020.1691996
NLM
Batista F de A, Gyau B, Santos JFVMR dos, Bosch SS, Lunev S, Wrenger C, Groves MR. New directions in antimalarial target validation [Internet]. Expert Opinion on Drug Discovery. 2020 ; 15( 2): 189–202.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1080/17460441.2020.1691996
Vancouver
Batista F de A, Gyau B, Santos JFVMR dos, Bosch SS, Lunev S, Wrenger C, Groves MR. New directions in antimalarial target validation [Internet]. Expert Opinion on Drug Discovery. 2020 ; 15( 2): 189–202.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1080/17460441.2020.1691996
Artigo de periodico
Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2 (2020)
Bosch, Soraya Soledad ; Lunev, Sergey ; Batista, Fernando de Assis ; Linzke, Marleen; Kronenberger, Thales ; Dömling, Alexander S. S. ; Groves, Matthew R. ; Wrenger, Carsten
Source: ACS Infectious Diseases. Unidade: ICB
Subjects: PARASITOLOGIA, COMPOSTOS ORGÂNICOS, PLASMODIUM FALCIPARUM, ASPARTATO CARBAMOILTRANSFERASE, ANIMAIS PARASITOS, MUTAÇÃO, ANTIMALÁRICOS, ATIVAÇÃO ENZIMÁTICA, MALÁRIA, ANIMAIS PARASITOS
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ABNT
BOSCH, Soraya Soledad et al. Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2. ACS Infectious Diseases, v. 6. n. 5, p. 986-999, 2020Tradução . . Disponível em: https://doi.org/10.1021/acsinfecdis.9b00411. Acesso em: 07 nov. 2024.
APA
Bosch, S. S., Lunev, S., Batista, F. de A., Linzke, M., Kronenberger, T., Dömling, A. S. S., et al. (2020). Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2. ACS Infectious Diseases, 6. n. 5, 986-999. doi:10.1021/acsinfecdis.9b00411
NLM
Bosch SS, Lunev S, Batista F de A, Linzke M, Kronenberger T, Dömling ASS, Groves MR, Wrenger C. Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2 [Internet]. ACS Infectious Diseases. 2020 ; 6. n. 5 986-999.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1021/acsinfecdis.9b00411
Vancouver
Bosch SS, Lunev S, Batista F de A, Linzke M, Kronenberger T, Dömling ASS, Groves MR, Wrenger C. Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2 [Internet]. ACS Infectious Diseases. 2020 ; 6. n. 5 986-999.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1021/acsinfecdis.9b00411
Artigo de periodico
Live and let dye: visualizing the cellular compartmentsof the malaria parasite Plasmodium falciparum (2020)
Linzke, Marleen; Yan, Sun Liu Rei ; Tárnok, Attila ; Ulrich, Henning ; Groves, Matthew R. ; Wrenger, Carsten
Source: Cytometry. Part A. Unidades: ICB, IQ
Subjects: PARASITOLOGIA, MALÁRIA, PLASMODIUM FALCIPARUM, MICROSCOPIA DE FLUORESCÊNCIA
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ABNT
LINZKE, Marleen et al. Live and let dye: visualizing the cellular compartmentsof the malaria parasite Plasmodium falciparum. Cytometry. Part A, v. 97, n. 7, p. 694-705, 2020Tradução . . Disponível em: https://doi.org/10.1002/cyto.a.23927. Acesso em: 07 nov. 2024.
APA
Linzke, M., Yan, S. L. R., Tárnok, A., Ulrich, H., Groves, M. R., & Wrenger, C. (2020). Live and let dye: visualizing the cellular compartmentsof the malaria parasite Plasmodium falciparum. Cytometry. Part A, 97( 7), 694-705. doi:10.1002/cyto.a.23927
NLM
Linzke M, Yan SLR, Tárnok A, Ulrich H, Groves MR, Wrenger C. Live and let dye: visualizing the cellular compartmentsof the malaria parasite Plasmodium falciparum [Internet]. Cytometry. Part A. 2020 ; 97( 7): 694-705.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1002/cyto.a.23927
Vancouver
Linzke M, Yan SLR, Tárnok A, Ulrich H, Groves MR, Wrenger C. Live and let dye: visualizing the cellular compartmentsof the malaria parasite Plasmodium falciparum [Internet]. Cytometry. Part A. 2020 ; 97( 7): 694-705.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1002/cyto.a.23927
Artigo de periodico
Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum (2019)
Batista, Fernando A. ; Bosch, Soraya Soledad ; Butzloff, Sabine; Lunev, Sergey; Müller, Ingrid B.; Dömling, Alexander S. S. ; Groves, Matthew R. ; Wrenger, Carsten
Source: Microbiology Open. Unidade: ICB
Subjects: PARASITOLOGIA, PLASMODIUM FALCIPARUM, MALÁRIA, PROTEÍNAS, ENZIMAS, ANTIMALÁRICOS
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ABNT
BATISTA, Fernando A. et al. Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum. Microbiology Open, p. 1-14, 2019Tradução . . Disponível em: https://doi.org/10.1002/mbo3.779. Acesso em: 07 nov. 2024.
APA
Batista, F. A., Bosch, S. S., Butzloff, S., Lunev, S., Müller, I. B., Dömling, A. S. S., et al. (2019). Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum. Microbiology Open, 1-14. doi:10.1002/mbo3.779
NLM
Batista FA, Bosch SS, Butzloff S, Lunev S, Müller IB, Dömling ASS, Groves MR, Wrenger C. Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum [Internet]. Microbiology Open. 2019 ; 1-14.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1002/mbo3.779
Vancouver
Batista FA, Bosch SS, Butzloff S, Lunev S, Müller IB, Dömling ASS, Groves MR, Wrenger C. Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum [Internet]. Microbiology Open. 2019 ; 1-14.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1002/mbo3.779
Artigo de periodico
Identiﬁcation of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase (2018)
Lunev, Sergey ; Bosch, Soraya S. ; Batista, Fernando A.; Wang, Chao; Li, Jingyao; Linzke, Marleen; Kruithof, Paul; Chamoun, George; Domling, Alexander S.S. ; Wrenger, Carsten ; Groves, Matthew R.
Source: Biochemical and Biophysical Research Communications. Unidade: ICB
Subjects: PARASITOLOGIA, PLASMODIUM FALCIPARUM, MALÁRIA
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ABNT
LUNEV, Sergey et al. Identiﬁcation of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase. Biochemical and Biophysical Research Communications, v. 497, n. 3, p. 835-842, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.bbrc.2018.02.112. Acesso em: 07 nov. 2024.
APA
Lunev, S., Bosch, S. S., Batista, F. A., Wang, C., Li, J., Linzke, M., et al. (2018). Identiﬁcation of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase. Biochemical and Biophysical Research Communications, 497(3), 835-842. doi:10.1016/j.bbrc.2018.02.112
NLM
Lunev S, Bosch SS, Batista FA, Wang C, Li J, Linzke M, Kruithof P, Chamoun G, Domling ASS, Wrenger C, Groves MR. Identiﬁcation of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase [Internet]. Biochemical and Biophysical Research Communications. 2018 ; 497(3): 835-842.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1016/j.bbrc.2018.02.112
Vancouver
Lunev S, Bosch SS, Batista FA, Wang C, Li J, Linzke M, Kruithof P, Chamoun G, Domling ASS, Wrenger C, Groves MR. Identiﬁcation of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase [Internet]. Biochemical and Biophysical Research Communications. 2018 ; 497(3): 835-842.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1016/j.bbrc.2018.02.112
Artigo de periodico
Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro (2018)
Lunev, Sergey; Butzloff, Sabine; Romero, Atilio R.; Linzke, Marleen; Batista, Fernando A.; Meissner, Kamila A.; Müller, Ingrid B.; Adawy, Alaa; Wrenger, Carsten ; Groves, Matthew R.
Source: PLOS ONE. Unidade: ICB
Subjects: PARASITOLOGIA, PLASMODIUM FALCIPARUM, MALÁRIA
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ABNT
LUNEV, Sergey et al. Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro. PLOS ONE, v. 13, n. 4, p. e0195011, 2018Tradução . . Disponível em: https://doi.org/10.1371/journal.pone.0195011. Acesso em: 07 nov. 2024.
APA
Lunev, S., Butzloff, S., Romero, A. R., Linzke, M., Batista, F. A., Meissner, K. A., et al. (2018). Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro. PLOS ONE, 13( 4), e0195011. doi:10.1371/journal.pone.0195011
NLM
Lunev S, Butzloff S, Romero AR, Linzke M, Batista FA, Meissner KA, Müller IB, Adawy A, Wrenger C, Groves MR. Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro [Internet]. PLOS ONE. 2018 ;13( 4): e0195011.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1371/journal.pone.0195011
Vancouver
Lunev S, Butzloff S, Romero AR, Linzke M, Batista FA, Meissner KA, Müller IB, Adawy A, Wrenger C, Groves MR. Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro [Internet]. PLOS ONE. 2018 ;13( 4): e0195011.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1371/journal.pone.0195011
Artigo de periodico
Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum (2016)
Lunev, Sergey ; Bosch, Soraya Soledad ; Batista, Fernando de Assis ; Wrenger, Carsten ; Groves, Matthew R.
Source: Acta Crystallographica. Section F: Structural Biology Communications. Unidade: ICB
Subjects: PARASITOLOGIA, BENZENO, COMPOSTOS ORGÂNICOS, RAIOS X, MALÁRIA, ANTIMALÁRICOS, ASPARTATO CARBAMOILTRANSFERASE, ATIVAÇÃO ENZIMÁTICA, MUTAGÊNESE
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ABNT
LUNEV, Sergey et al. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallographica. Section F: Structural Biology Communications, v. 72, p. 523-533, 2016Tradução . . Disponível em: https://doi.org/10.1107/S2053230X16008475. Acesso em: 07 nov. 2024.
APA
Lunev, S., Bosch, S. S., Batista, F. de A., Wrenger, C., & Groves, M. R. (2016). Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallographica. Section F: Structural Biology Communications, 72, 523-533. doi:10.1107/S2053230X16008475
NLM
Lunev S, Bosch SS, Batista F de A, Wrenger C, Groves MR. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum [Internet]. Acta Crystallographica. Section F: Structural Biology Communications. 2016 ; 72 523-533.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1107/S2053230X16008475
Vancouver
Lunev S, Bosch SS, Batista F de A, Wrenger C, Groves MR. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum [Internet]. Acta Crystallographica. Section F: Structural Biology Communications. 2016 ; 72 523-533.[citado 2024 nov. 07 ] Available from: https://doi.org/10.1107/S2053230X16008475

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