ReP USP - Resultado da busca

Artigo de periodico
Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in uncomplicated malaria (2022)
Taft, Benjamin R.; Aguiar, Anna Caroline Campos
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: ANTIMALÁRICOS, PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, ANTIPARASITÁRIOS, MALÁRIA, BIOQUÍMICA, QUÍMICA MÉDICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
TAFT, Benjamin R.; AGUIAR, Anna Caroline Campos. Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in uncomplicated malaria. Journal of Medicinal Chemistry, Washington, DC, v. 65, n. 5, p. 3798-3813, 2022. Disponível em: < http://dx.doi.org/10.1021/acs.jmedchem.1c01995 > DOI: 10.1021/acs.jmedchem.1c01995.
APA
Taft, B. R., & Aguiar, A. C. C. (2022). Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in uncomplicated malaria. Journal of Medicinal Chemistry, 65( 5), 3798-3813. doi:10.1021/acs.jmedchem.1c01995
NLM
Taft BR, Aguiar ACC. Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in uncomplicated malaria [Internet]. Journal of Medicinal Chemistry. 2022 ; 65( 5): 3798-3813.Available from: http://dx.doi.org/10.1021/acs.jmedchem.1c01995
Vancouver
Taft BR, Aguiar ACC. Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in uncomplicated malaria [Internet]. Journal of Medicinal Chemistry. 2022 ; 65( 5): 3798-3813.Available from: http://dx.doi.org/10.1021/acs.jmedchem.1c01995
Artigo de periodico
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series (2021)
Palmer, Michael J.; Aguiar, Anna Caroline Campos; Guido, Rafael Victorio Carvalho
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: ANTIMALÁRICOS, PLASMODIUM FALCIPARUM, PLANEJAMENTO DE FÁRMACOS, ANTIPARASITÁRIOS, MALÁRIA, BIOQUÍMICA, QUÍMICA MÉDICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
PALMER, Michael J.; AGUIAR, Anna Caroline Campos; GUIDO, Rafael Victorio Carvalho. Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series. Journal of Medicinal Chemistry, Washington, DC, v. 64, n. 9, p. 6085-6136, 2021. Disponível em: < http://dx.doi.org/10.1021/acs.jmedchem.1c00173 > DOI: 10.1021/acs.jmedchem.1c00173.
APA
Palmer, M. J., Aguiar, A. C. C., & Guido, R. V. C. (2021). Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series. Journal of Medicinal Chemistry, 64( 9), 6085-6136. doi:10.1021/acs.jmedchem.1c00173
NLM
Palmer MJ, Aguiar ACC, Guido RVC. Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series [Internet]. Journal of Medicinal Chemistry. 2021 ; 64( 9): 6085-6136.Available from: http://dx.doi.org/10.1021/acs.jmedchem.1c00173
Vancouver
Palmer MJ, Aguiar ACC, Guido RVC. Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series [Internet]. Journal of Medicinal Chemistry. 2021 ; 64( 9): 6085-6136.Available from: http://dx.doi.org/10.1021/acs.jmedchem.1c00173
Artigo de periodico
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? (2019)
Cianni, Lorenzo ; Feldmann, CW; Gilberg, E; Gütschow Michaell; Juliano, Luiz; Leitão, Andrei ; Bajorath, Jurgen; Montanari, Carlos Alberto
Source: Journal of Medicinal Chemistry. Unidade: IQSC
Subject: NEOPLASIAS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
CIANNI, Lorenzo; FELDMANN, CW; GILBERG, E; et al. Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? Journal of Medicinal Chemistry, Washington, v. 62, n. 23, p. 10497-10525 july, 2019. Disponível em: < https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00683 > DOI: 10.1021/acs.jmedchem.9b00683.
APA
Cianni, L., Feldmann, C. W., Gilberg, E., Gütschow Michaell,, Juliano, L., Leitão, A., et al. (2019). Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? Journal of Medicinal Chemistry, 62( 23), 10497-10525 july. doi:10.1021/acs.jmedchem.9b00683
NLM
Cianni L, Feldmann CW, Gilberg E, Gütschow Michaell, Juliano L, Leitão A, Bajorath J, Montanari CA. Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? [Internet]. Journal of Medicinal Chemistry. 2019 ; 62( 23): 10497-10525 july.Available from: https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00683
Vancouver
Cianni L, Feldmann CW, Gilberg E, Gütschow Michaell, Juliano L, Leitão A, Bajorath J, Montanari CA. Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? [Internet]. Journal of Medicinal Chemistry. 2019 ; 62( 23): 10497-10525 july.Available from: https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00683
Artigo de periodico
Discovery of marinoquinolines as potent and fast-acting plasmodium falciparum inhibitors with in Vivo activity (2018)
Aguiar, Anna Caroline Campos; Panciera, Michele; Santos, Eric Francisco Simão dos; Singh, Maneesh Kumar; Garcia, Mariana Lopes; Guido, Rafael Victorio Carvalho; Souza, Guilherme Eduardo de; Nakabashi, Myna; Costa, José Luiz; Garcia, Célia Regina da Silva ; Oliva, Glaucius; Correia, Carlos Roque Duarte; Guido, Rafael Victorio Carvalho
Source: Journal of Medicinal Chemistry. Unidades: IB, IFSC
Subjects: PLASMODIUM FALCIPARUM, MALÁRIA, PLANEJAMENTO DE FÁRMACOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
AGUIAR, Anna Caroline Campos; PANCIERA, Michele; SANTOS, Eric Francisco Simão dos; et al. Discovery of marinoquinolines as potent and fast-acting plasmodium falciparum inhibitors with in Vivo activity. Journal of Medicinal Chemistry, Washington, DC, v. 61, n. 13, p. 5547-5568, 2018. Disponível em: < http://dx.doi.org/10.1021/acs.jmedchem.8b00143 > DOI: 10.1021/acs.jmedchem.8b00143.
APA
Aguiar, A. C. C., Panciera, M., Santos, E. F. S. dos, Singh, M. K., Garcia, M. L., Guido, R. V. C., et al. (2018). Discovery of marinoquinolines as potent and fast-acting plasmodium falciparum inhibitors with in Vivo activity. Journal of Medicinal Chemistry, 61( 13), 5547-5568. doi:10.1021/acs.jmedchem.8b00143
NLM
Aguiar ACC, Panciera M, Santos EFS dos, Singh MK, Garcia ML, Guido RVC, Souza GE de, Nakabashi M, Costa JL, Garcia CR da S, Oliva G, Correia CRD, Guido RVC. Discovery of marinoquinolines as potent and fast-acting plasmodium falciparum inhibitors with in Vivo activity [Internet]. Journal of Medicinal Chemistry. 2018 ; 61( 13): 5547-5568.Available from: http://dx.doi.org/10.1021/acs.jmedchem.8b00143
Vancouver
Aguiar ACC, Panciera M, Santos EFS dos, Singh MK, Garcia ML, Guido RVC, Souza GE de, Nakabashi M, Costa JL, Garcia CR da S, Oliva G, Correia CRD, Guido RVC. Discovery of marinoquinolines as potent and fast-acting plasmodium falciparum inhibitors with in Vivo activity [Internet]. Journal of Medicinal Chemistry. 2018 ; 61( 13): 5547-5568.Available from: http://dx.doi.org/10.1021/acs.jmedchem.8b00143
Artigo de periodico
The synthesized plant metabolite 3,4,5-tri-o-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells (2018)
Abd El-Salam, Mohamed ; Bastos, Jairo Kenupp; Han, Jing Jing; Previdi, Daniel ; Coelho, Eduardo Barbosa ; Donate, Paulo Marcos ; Romero, Michael F.; Lieske, John
Source: Journal of Medicinal Chemistry. Unidades: FCFRP, FMRP, FFCLRP
Subjects: FRAÇÕES SUBCELULARES, CÉLULAS, RIM, ANTIOXIDANTES, DROSOPHILA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
ABD EL-SALAM, Mohamed; BASTOS, Jairo Kenupp; HAN, Jing Jing; et al. The synthesized plant metabolite 3,4,5-tri-o-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells. Journal of Medicinal Chemistry, Washington, v. 61, n. 4, p. 1609-1621, 2018. Disponível em: < http://dx.doi.org/10.1021/acs.jmedchem.7b01566 > DOI: 10.1021/acs.jmedchem.7b01566.
APA
Abd El-Salam, M., Bastos, J. K., Han, J. J., Previdi, D., Coelho, E. B., Donate, P. M., et al. (2018). The synthesized plant metabolite 3,4,5-tri-o-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells. Journal of Medicinal Chemistry, 61( 4), 1609-1621. doi:10.1021/acs.jmedchem.7b01566
NLM
Abd El-Salam M, Bastos JK, Han JJ, Previdi D, Coelho EB, Donate PM, Romero MF, Lieske J. The synthesized plant metabolite 3,4,5-tri-o-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells [Internet]. Journal of Medicinal Chemistry. 2018 ; 61( 4): 1609-1621.Available from: http://dx.doi.org/10.1021/acs.jmedchem.7b01566
Vancouver
Abd El-Salam M, Bastos JK, Han JJ, Previdi D, Coelho EB, Donate PM, Romero MF, Lieske J. The synthesized plant metabolite 3,4,5-tri-o-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells [Internet]. Journal of Medicinal Chemistry. 2018 ; 61( 4): 1609-1621.Available from: http://dx.doi.org/10.1021/acs.jmedchem.7b01566
Artigo de periodico
Hydrogen bond basicity prediction for medicinal chemistry design (2016)
Kenny, Peter W; Montanari, Carlos Alberto; Prokopczyk, Igor Muccilo; Ribeiro, Jean Francisco Rosa; Sartori, Geraldo Rodrigues
Source: Journal of Medicinal Chemistry. Unidade: IQSC
Subject: QUÍMICA MÉDICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
KENNY, Peter W; MONTANARI, Carlos Alberto; PROKOPCZYK, Igor Muccilo; RIBEIRO, Jean Francisco Rosa; SARTORI, Geraldo Rodrigues. Hydrogen bond basicity prediction for medicinal chemistry design. Journal of Medicinal Chemistry, Washington, v. 59, n. 9, p. 4278-4288, 2016. DOI: 10.1021/acs.jmedchem.5b01946.
APA
Kenny, P. W., Montanari, C. A., Prokopczyk, I. M., Ribeiro, J. F. R., & Sartori, G. R. (2016). Hydrogen bond basicity prediction for medicinal chemistry design. Journal of Medicinal Chemistry, 59( 9), 4278-4288. doi:10.1021/acs.jmedchem.5b01946
NLM
Kenny PW, Montanari CA, Prokopczyk IM, Ribeiro JFR, Sartori GR. Hydrogen bond basicity prediction for medicinal chemistry design. Journal of Medicinal Chemistry. 2016 ; 59( 9): 4278-4288.
Vancouver
Kenny PW, Montanari CA, Prokopczyk IM, Ribeiro JFR, Sartori GR. Hydrogen bond basicity prediction for medicinal chemistry design. Journal of Medicinal Chemistry. 2016 ; 59( 9): 4278-4288.
Artigo de periodico
Anti-inflammatory and anti-nociceptive activity of ruthenium complexes with isonicotinic and nicotinic acids (Niacin) as ligands (2015)
Freitas, Cristina S; Roveda Júnior, Antonio Carlos; Truzzi, Daniela Ramos ; Garcia, André Castilho; Cunha, Thiago Mattar; Cunha, Fernando Queiróz; Franco, Douglas Wagner
Source: Journal of Medicinal Chemistry. Unidades: FMRP, IQSC
Subjects: ANTI-INFLAMATÓRIOS NÃO ESTEROIDES, QUÍMICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
FREITAS, Cristina S; ROVEDA JÚNIOR, Antonio Carlos; TRUZZI, Daniela Ramos; et al. Anti-inflammatory and anti-nociceptive activity of ruthenium complexes with isonicotinic and nicotinic acids (Niacin) as ligands. Journal of Medicinal Chemistry, Washington, 2015. Disponível em: < http://dx.doi.org/10.1021/acs.jmedchem.5b00133 > DOI: 10.1021/acs.jmedchem.5b00133.
APA
Freitas, C. S., Roveda Júnior, A. C., Truzzi, D. R., Garcia, A. C., Cunha, T. M., Cunha, F. Q., & Franco, D. W. (2015). Anti-inflammatory and anti-nociceptive activity of ruthenium complexes with isonicotinic and nicotinic acids (Niacin) as ligands. Journal of Medicinal Chemistry. doi:10.1021/acs.jmedchem.5b00133
NLM
Freitas CS, Roveda Júnior AC, Truzzi DR, Garcia AC, Cunha TM, Cunha FQ, Franco DW. Anti-inflammatory and anti-nociceptive activity of ruthenium complexes with isonicotinic and nicotinic acids (Niacin) as ligands [Internet]. Journal of Medicinal Chemistry. 2015 ;Available from: http://dx.doi.org/10.1021/acs.jmedchem.5b00133
Vancouver
Freitas CS, Roveda Júnior AC, Truzzi DR, Garcia AC, Cunha TM, Cunha FQ, Franco DW. Anti-inflammatory and anti-nociceptive activity of ruthenium complexes with isonicotinic and nicotinic acids (Niacin) as ligands [Internet]. Journal of Medicinal Chemistry. 2015 ;Available from: http://dx.doi.org/10.1021/acs.jmedchem.5b00133
Artigo de periodico
2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents (2015)
Bardiot, Dorothée; Marchand, Arnaud; Thevissen, Karin; Brucker, Katrijn De; Peeters, Annelies; Cos, Paul; Taborda, Carlos Pelleschi; McNaughton, Michael; Maes, Louis; Chaltin, Patrick; Cammue, Bruno P. A.
Source: Journal of Medicinal Chemistry. Unidade: ICB
Subjects: MICROBIOLOGIA, FUNGICIDAS, CANDIDA ALBICANS, ANTIFUNGICOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
BARDIOT, Dorothée; MARCHAND, Arnaud; THEVISSEN, Karin; et al. 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents. Journal of Medicinal Chemistry, Washington, v. 58, n. 3, p. 1502-1512, 2015. Disponível em: < http://dx.doi.org/10.1021/jm501814x > DOI: 10.1021/jm501814x.
APA
Bardiot, D., Marchand, A., Thevissen, K., Brucker, K. D., Peeters, A., Cos, P., et al. (2015). 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents. Journal of Medicinal Chemistry, 58( 3), 1502-1512. doi:10.1021/jm501814x
NLM
Bardiot D, Marchand A, Thevissen K, Brucker KD, Peeters A, Cos P, Taborda CP, McNaughton M, Maes L, Chaltin P, Cammue BPA. 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents [Internet]. Journal of Medicinal Chemistry. 2015 ; 58( 3): 1502-1512.Available from: http://dx.doi.org/10.1021/jm501814x
Vancouver
Bardiot D, Marchand A, Thevissen K, Brucker KD, Peeters A, Cos P, Taborda CP, McNaughton M, Maes L, Chaltin P, Cammue BPA. 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents [Internet]. Journal of Medicinal Chemistry. 2015 ; 58( 3): 1502-1512.Available from: http://dx.doi.org/10.1021/jm501814x
Artigo de periodico
Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents (2014)
Ferreira, Rafaela S.; Dessoy, Marco A.; Pauli, Ivani; Souza, Mariana L.; Krogh, Renata; Sales, Ana I. L.; Oliva, Glaucius; Dias, Luiz C.; Andricopulo, Adriano Defini
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: PLANEJAMENTO DE FÁRMACOS, TRYPANOSOMA CRUZI, DOENÇA DE CHAGAS (TRATAMENTO)
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
FERREIRA, Rafaela S.; DESSOY, Marco A.; PAULI, Ivani; et al. Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents. Journal of Medicinal Chemistry, Washington, DC, v. 57, n. 6, p. 2380-2392, 2014. Disponível em: < http://dx.doi.org/10.1021/jm401709b > DOI: 10.1021/jm401709b.
APA
Ferreira, R. S., Dessoy, M. A., Pauli, I., Souza, M. L., Krogh, R., Sales, A. I. L., et al. (2014). Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents. Journal of Medicinal Chemistry, 57( 6), 2380-2392. doi:10.1021/jm401709b
NLM
Ferreira RS, Dessoy MA, Pauli I, Souza ML, Krogh R, Sales AIL, Oliva G, Dias LC, Andricopulo AD. Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents [Internet]. Journal of Medicinal Chemistry. 2014 ; 57( 6): 2380-2392.Available from: http://dx.doi.org/10.1021/jm401709b
Vancouver
Ferreira RS, Dessoy MA, Pauli I, Souza ML, Krogh R, Sales AIL, Oliva G, Dias LC, Andricopulo AD. Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents [Internet]. Journal of Medicinal Chemistry. 2014 ; 57( 6): 2380-2392.Available from: http://dx.doi.org/10.1021/jm401709b
Artigo de periodico
Acetylcholinesterase immobilized capillary reactors–tandem mass spectrometry: an on-flow tool for ligand screening (2013)
Vanzolini, Kenia L.; Vieira, Lucas C. C.; Corrêa, Arlene G.; Cardoso, Cármen Lúcia; Cass, Quezia B.
Source: Journal of Medicinal Chemistry. Unidade: FFCLRP
Subjects: ENZIMAS, CROMATOGRAFIA LÍQUIDA, ESPECTROSCOPIA DE MASSA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
VANZOLINI, Kenia L.; VIEIRA, Lucas C. C.; CORRÊA, Arlene G.; CARDOSO, Cármen Lúcia; CASS, Quezia B. Acetylcholinesterase immobilized capillary reactors–tandem mass spectrometry: an on-flow tool for ligand screening. Journal of Medicinal Chemistry, Washington, v. 56, p. 2038-2044, 2013. Disponível em: < http://dx.doi.org/10.1021/jm301732a >.
APA
Vanzolini, K. L., Vieira, L. C. C., Corrêa, A. G., Cardoso, C. L., & Cass, Q. B. (2013). Acetylcholinesterase immobilized capillary reactors–tandem mass spectrometry: an on-flow tool for ligand screening. Journal of Medicinal Chemistry, 56, 2038-2044. Recuperado de http://dx.doi.org/10.1021/jm301732a
NLM
Vanzolini KL, Vieira LCC, Corrêa AG, Cardoso CL, Cass QB. Acetylcholinesterase immobilized capillary reactors–tandem mass spectrometry: an on-flow tool for ligand screening [Internet]. Journal of Medicinal Chemistry. 2013 ; 56 2038-2044.Available from: http://dx.doi.org/10.1021/jm301732a
Vancouver
Vanzolini KL, Vieira LCC, Corrêa AG, Cardoso CL, Cass QB. Acetylcholinesterase immobilized capillary reactors–tandem mass spectrometry: an on-flow tool for ligand screening [Internet]. Journal of Medicinal Chemistry. 2013 ; 56 2038-2044.Available from: http://dx.doi.org/10.1021/jm301732a
Artigo de periodico
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain (2013)
Ferguson, Fleur M.; Ciulli, Alessio; Fedorov, Oleg; Chaikuad, Apirat; Philpott, Martin; Muniz, João Renato Carvalho; Felletar, Ildiko; Delft, Frank von; Heightman, Tom; Knapp, Stefan; Abell, Chris
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: INIBIDORES DE ENZIMAS, PLANEJAMENTO DE FÁRMACOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
FERGUSON, Fleur M.; CIULLI, Alessio; FEDOROV, Oleg; et al. Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. Journal of Medicinal Chemistry, Washington, DC, v. 56, n. 24, p. 10183-10187, 2013. Disponível em: < http://dx.doi.org/10.1021/jm401582c > DOI: 10.1021/jm401582c.
APA
Ferguson, F. M., Ciulli, A., Fedorov, O., Chaikuad, A., Philpott, M., Muniz, J. R. C., et al. (2013). Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. Journal of Medicinal Chemistry, 56( 24), 10183-10187. doi:10.1021/jm401582c
NLM
Ferguson FM, Ciulli A, Fedorov O, Chaikuad A, Philpott M, Muniz JRC, Felletar I, Delft F von, Heightman T, Knapp S, Abell C. Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain [Internet]. Journal of Medicinal Chemistry. 2013 ; 56( 24): 10183-10187.Available from: http://dx.doi.org/10.1021/jm401582c
Vancouver
Ferguson FM, Ciulli A, Fedorov O, Chaikuad A, Philpott M, Muniz JRC, Felletar I, Delft F von, Heightman T, Knapp S, Abell C. Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain [Internet]. Journal of Medicinal Chemistry. 2013 ; 56( 24): 10183-10187.Available from: http://dx.doi.org/10.1021/jm401582c
Artigo de periodico
Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors os Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA an PtpB) (2012)
Chiaradia, Louise Domeneghini; Yunes, Rosendo Augusto; Vernal, Javier; Nunes, Ricardo José; Terenzi, Hernán; Martins, Priscila Graziela Alves; Cordeiro, Marlon Norberto Sechini; Guido, Rafael Victorio Carvalho; Ecco, Gabriela; Andricopulo, Adriano Defini
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: MYCOBACTERIUM TUBERCULOSIS (ESTUDO;TRATAMENTO), INIBIDORES DE ENZIMAS, PLANEJAMENTO DE FÁRMACOS, MODELAGEM MOLECULAR
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
CHIARADIA, Louise Domeneghini; YUNES, Rosendo Augusto; VERNAL, Javier; et al. Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors os Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA an PtpB). Journal of Medicinal Chemistry, Washington, DC, v. 55, n. Ja 2012, p. 390-402, 2012. Disponível em: < http://dx.doi.org/10.1021/jm2012062 > DOI: 10.1021/jm2012062.
APA
Chiaradia, L. D., Yunes, R. A., Vernal, J., Nunes, R. J., Terenzi, H., Martins, P. G. A., et al. (2012). Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors os Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA an PtpB). Journal of Medicinal Chemistry, 55( Ja 2012), 390-402. doi:10.1021/jm2012062
NLM
Chiaradia LD, Yunes RA, Vernal J, Nunes RJ, Terenzi H, Martins PGA, Cordeiro MNS, Guido RVC, Ecco G, Andricopulo AD. Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors os Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA an PtpB) [Internet]. Journal of Medicinal Chemistry. 2012 ; 55( Ja 2012): 390-402.Available from: http://dx.doi.org/10.1021/jm2012062
Vancouver
Chiaradia LD, Yunes RA, Vernal J, Nunes RJ, Terenzi H, Martins PGA, Cordeiro MNS, Guido RVC, Ecco G, Andricopulo AD. Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors os Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA an PtpB) [Internet]. Journal of Medicinal Chemistry. 2012 ; 55( Ja 2012): 390-402.Available from: http://dx.doi.org/10.1021/jm2012062
Artigo de periodico
Complexation of the anti-trypanosoma cruzi drug benznidazole improves solubility and efficacy (2008)
Silva, Jean Jerley Nogueira; Pavanelli, Wander Rogério; Salazar Gutierrez, Fredy R.; Lima, Francisco Chagas Alves; Silva, Alberico Borges Ferreira da; Silva, João Santana da; Franco, Douglas Wagner
Source: Journal of Medicinal Chemistry. Unidades: IQSC, FMRP
Subjects: TRYPANOSOMA CRUZI, QUÍMICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
SILVA, Jean Jerley Nogueira; PAVANELLI, Wander Rogério; SALAZAR GUTIERREZ, Fredy R.; et al. Complexation of the anti-trypanosoma cruzi drug benznidazole improves solubility and efficacy. Journal of Medicinal Chemistry, Washington, v. 51, n. 4, p. 4104-4114, 2008. Disponível em: < http://pubs.acs.org/cgi-bin/article.cgi/jmcmar/2008/51/i14/pdf/jm701306r.pdf >.
APA
Silva, J. J. N., Pavanelli, W. R., Salazar Gutierrez, F. R., Lima, F. C. A., Silva, A. B. F. da, Silva, J. S. da, & Franco, D. W. (2008). Complexation of the anti-trypanosoma cruzi drug benznidazole improves solubility and efficacy. Journal of Medicinal Chemistry, 51( 4), 4104-4114. Recuperado de http://pubs.acs.org/cgi-bin/article.cgi/jmcmar/2008/51/i14/pdf/jm701306r.pdf
NLM
Silva JJN, Pavanelli WR, Salazar Gutierrez FR, Lima FCA, Silva ABF da, Silva JS da, Franco DW. Complexation of the anti-trypanosoma cruzi drug benznidazole improves solubility and efficacy [Internet]. Journal of Medicinal Chemistry. 2008 ; 51( 4): 4104-4114.Available from: http://pubs.acs.org/cgi-bin/article.cgi/jmcmar/2008/51/i14/pdf/jm701306r.pdf
Vancouver
Silva JJN, Pavanelli WR, Salazar Gutierrez FR, Lima FCA, Silva ABF da, Silva JS da, Franco DW. Complexation of the anti-trypanosoma cruzi drug benznidazole improves solubility and efficacy [Internet]. Journal of Medicinal Chemistry. 2008 ; 51( 4): 4104-4114.Available from: http://pubs.acs.org/cgi-bin/article.cgi/jmcmar/2008/51/i14/pdf/jm701306r.pdf
Artigo de periodico
Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets (2006)
Otero, Lucía; Vieites, Marisol; Boiani, Lucía; Denicola, Ana; Rigol, Carolina; Opazo, Lucia; Azar, Claudio Olea; Maya, Juan Diego; Morello, Antonio; Siegel, R. Luise Krauth; Piro, Oscar E.; Castellano, Eduardo Ernesto; González, Mercedes; Gambino, Dinorah; Cerecetto, Hugo (Universidad de la República, Departamento de Química Orgánica, Montevideo, Uruguay)
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: DOENÇA DE CHAGAS, DOENÇAS INFECCIOSAS, DNA, REDUÇÃO, DIFRAÇÃO POR RAIOS X, TRYPANOSOMA CRUZI
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
OTERO, Lucía; VIEITES, Marisol; BOIANI, Lucía; et al. Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets. Journal of Medicinal Chemistry, Washington, DC, v. 49, n. Ju 2006, p. 3322-3331, 2006.
APA
Otero, L., Vieites, M., Boiani, L., Denicola, A., Rigol, C., Opazo, L., et al. (2006). Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets. Journal of Medicinal Chemistry, 49( Ju 2006), 3322-3331.
NLM
Otero L, Vieites M, Boiani L, Denicola A, Rigol C, Opazo L, Azar CO, Maya JD, Morello A, Siegel RLK, Piro OE, Castellano EE, González M, Gambino D, Cerecetto H. Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets. Journal of Medicinal Chemistry. 2006 ;49( Ju 2006): 3322-3331.
Vancouver
Otero L, Vieites M, Boiani L, Denicola A, Rigol C, Opazo L, Azar CO, Maya JD, Morello A, Siegel RLK, Piro OE, Castellano EE, González M, Gambino D, Cerecetto H. Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets. Journal of Medicinal Chemistry. 2006 ;49( Ju 2006): 3322-3331.
Artigo de periodico
Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands (2006)
Martínez, Leandro; Webb, Paul; Polikarpov, Igor; Skaf, Munir S.
Source: Journal of Medicinal Chemistry. Unidade: IFSC
Subjects: HORMÔNIOS TIREOIDIANOS, CRISTALOGRAFIA FÍSICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
MARTÍNEZ, Leandro; WEBB, Paul; POLIKARPOV, Igor; SKAF, Munir S. Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands. Journal of Medicinal Chemistry, Washington, v. 49, n. Ja 2006, p. 23-26, 2006.
APA
Martínez, L., Webb, P., Polikarpov, I., & Skaf, M. S. (2006). Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands. Journal of Medicinal Chemistry, 49( Ja 2006), 23-26.
NLM
Martínez L, Webb P, Polikarpov I, Skaf MS. Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands. Journal of Medicinal Chemistry. 2006 ;49( Ja 2006): 23-26.
Vancouver
Martínez L, Webb P, Polikarpov I, Skaf MS. Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands. Journal of Medicinal Chemistry. 2006 ;49( Ja 2006): 23-26.
Artigo de periodico
Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-'capa'B (2004)
Siedle, Bettina; Garcia-Piñeres, Alfonso J.; Murillo, Renato; Schulte-Mönting, Jürgen; Castro, Victor; Rüngeler, Peter; Klaas, Christoph A.; Costa, Fernando Batista da; Kisiel, Wanda; Merfort, Irmgard
Source: Journal of Medicinal Chemistry. Unidade: FCFRP
Subjects: SESQUITERPENOS, BIOQUÍMICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
SIEDLE, Bettina; GARCIA-PIÑERES, Alfonso J.; MURILLO, Renato; et al. Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-'capa'B. Journal of Medicinal Chemistry, Washington, v. 47, p. 6042-6054, 2004.
APA
Siedle, B., Garcia-Piñeres, A. J., Murillo, R., Schulte-Mönting, J., Castro, V., Rüngeler, P., et al. (2004). Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-'capa'B. Journal of Medicinal Chemistry, 47, 6042-6054.
NLM
Siedle B, Garcia-Piñeres AJ, Murillo R, Schulte-Mönting J, Castro V, Rüngeler P, Klaas CA, Costa FB da, Kisiel W, Merfort I. Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-'capa'B. Journal of Medicinal Chemistry. 2004 ; 47 6042-6054.
Vancouver
Siedle B, Garcia-Piñeres AJ, Murillo R, Schulte-Mönting J, Castro V, Rüngeler P, Klaas CA, Costa FB da, Kisiel W, Merfort I. Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-'capa'B. Journal of Medicinal Chemistry. 2004 ; 47 6042-6054.
Artigo de periodico
Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives (2004)
Pasqualoto, Kerly Fernanda Mesquita; Ferreira, Elizabeth Igne ; Santos Filho, Osvaldo Andrade; Hopfinger, Anton J.
Source: Journal of Medicinal Chemistry. Unidade: FCF
Subjects: FARMACOLOGIA, RELAÇÕES QUANTITATIVAS ENTRE ESTRUTURA QUÍMICA E ATIVIDADE BIOLÓGICA, MEDICAMENTO
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
PASQUALOTO, Kerly Fernanda Mesquita; FERREIRA, Elizabeth Igne; SANTOS FILHO, Osvaldo Andrade; HOPFINGER, Anton J. Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives. Journal of Medicinal Chemistry, Columbus, v. 47, n. 15, p. 3755-3764, 2004.
APA
Pasqualoto, K. F. M., Ferreira, E. I., Santos Filho, O. A., & Hopfinger, A. J. (2004). Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives. Journal of Medicinal Chemistry, 47( 15), 3755-3764.
NLM
Pasqualoto KFM, Ferreira EI, Santos Filho OA, Hopfinger AJ. Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives. Journal of Medicinal Chemistry. 2004 ; 47( 15): 3755-3764.
Vancouver
Pasqualoto KFM, Ferreira EI, Santos Filho OA, Hopfinger AJ. Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives. Journal of Medicinal Chemistry. 2004 ; 47( 15): 3755-3764.
Artigo de periodico
Introduction of a chemical constraint in a short peptide derived from human acidic fibroblast growth factor elicits mitogenic structural determinants (2003)
Kiyota, Sumika; Franzoni, Lorella; Nicastro, Giuseppe; Benedetti, Arianna; Oyama Júnior, Sérgio; Viviani, Wladia; Gambarini, Ângelo Geraldo; Spisni, Alberto; Miranda, Maria Terêsa Machini de
Source: Journal of Medicinal Chemistry. Unidade: IQ
Subjects: BIOQUÍMICA, FIBROBLASTOS, ESPECTROSCOPIA DE RESSONÂNCIA MAGNÉTICA NUCLEAR, RESÍDUOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
KIYOTA, Sumika; FRANZONI, Lorella; NICASTRO, Giuseppe; et al. Introduction of a chemical constraint in a short peptide derived from human acidic fibroblast growth factor elicits mitogenic structural determinants. Journal of Medicinal Chemistry, Washington, v. 46, n. 12, p. 2325-2333, 2003.
APA
Kiyota, S., Franzoni, L., Nicastro, G., Benedetti, A., Oyama Júnior, S., Viviani, W., et al. (2003). Introduction of a chemical constraint in a short peptide derived from human acidic fibroblast growth factor elicits mitogenic structural determinants. Journal of Medicinal Chemistry, 46( 12), 2325-2333.
NLM
Kiyota S, Franzoni L, Nicastro G, Benedetti A, Oyama Júnior S, Viviani W, Gambarini ÂG, Spisni A, Miranda MTM de. Introduction of a chemical constraint in a short peptide derived from human acidic fibroblast growth factor elicits mitogenic structural determinants. Journal of Medicinal Chemistry. 2003 ; 46( 12): 2325-2333.
Vancouver
Kiyota S, Franzoni L, Nicastro G, Benedetti A, Oyama Júnior S, Viviani W, Gambarini ÂG, Spisni A, Miranda MTM de. Introduction of a chemical constraint in a short peptide derived from human acidic fibroblast growth factor elicits mitogenic structural determinants. Journal of Medicinal Chemistry. 2003 ; 46( 12): 2325-2333.
Artigo de periodico
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead (2003)
Chauvière, Gérard; Bouteille, Bernard; Albuquerque, Cristina Northfleet de ; Croft, Simon L.; Dumas, Michel; Périe, Jacques
Source: Journal of Medicinal Chemistry. Unidade: FCF
Subjects: MEDICAMENTO (SÍNTESE), FARMACOLOGIA, TRYPANOSOMA CRUZI
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
CHAUVIÈRE, Gérard; BOUTEILLE, Bernard; ALBUQUERQUE, Cristina Northfleet de; et al. Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of Medicinal Chemistry, Washington, v. 46, n. 3, p. 427-440, 2003.
APA
Chauvière, G., Bouteille, B., Albuquerque, C. N. de, Croft, S. L., Dumas, M., & Périe, J. (2003). Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of Medicinal Chemistry, 46( 3), 427-440.
NLM
Chauvière G, Bouteille B, Albuquerque CN de, Croft SL, Dumas M, Périe J. Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of Medicinal Chemistry. 2003 ; 46( 3): 427-440.
Vancouver
Chauvière G, Bouteille B, Albuquerque CN de, Croft SL, Dumas M, Périe J. Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of Medicinal Chemistry. 2003 ; 46( 3): 427-440.
Artigo de periodico
A trypanocidal phenazine derived from 'BETA'-Lapachone (2002)
Pinto, Cleverson Neves; Malta, Valéria Rodrigues dos Santos; Pinto, Maria do Carmo F. R.; Santos, Regina Helena de Almeida; Castro, Solange L. de; Pinto, Antônio Ventura
Source: Journal of Medicinal Chemistry. Unidade: IQSC
Subjects: PRODUTOS NATURAIS, QUÍMICA
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
PINTO, Cleverson Neves; MALTA, Valéria Rodrigues dos Santos; PINTO, Maria do Carmo F. R.; et al. A trypanocidal phenazine derived from 'BETA'-Lapachone. Journal of Medicinal Chemistry, Washington, v. 45, p. 2112-2115, 2002.
APA
Pinto, C. N., Malta, V. R. dos S., Pinto, M. do C. F. R., Santos, R. H. de A., Castro, S. L. de, & Pinto, A. V. (2002). A trypanocidal phenazine derived from 'BETA'-Lapachone. Journal of Medicinal Chemistry, 45, 2112-2115.
NLM
Pinto CN, Malta VR dos S, Pinto M do CFR, Santos RH de A, Castro SL de, Pinto AV. A trypanocidal phenazine derived from 'BETA'-Lapachone. Journal of Medicinal Chemistry. 2002 ; 45 2112-2115.
Vancouver
Pinto CN, Malta VR dos S, Pinto M do CFR, Santos RH de A, Castro SL de, Pinto AV. A trypanocidal phenazine derived from 'BETA'-Lapachone. Journal of Medicinal Chemistry. 2002 ; 45 2112-2115.

USP Schools

ReP

Filters

USP Schools

Departament

Authors

USP affiliated authors

Date published

Subjects

Grupo de pesquisa

Funding Agencies

Indexado em

Normalized affiliation

Non normalized affiliation