Stable and cost-effective production of GCASE-OPT using a low MOI lentiviral approach for enzyme replacement therapy in gaucher disease: development of L20_HEF1A_GBA-OPT-R534H, a stable human cell line (2024)
- Authors:
- USP affiliated authors: WIEZEL, CLÁUDIA EMÍLIA VIEIRA - FMRP ; TIRAPELLI, DANIELA PRETTI DA CUNHA - FMRP ; RAMOS, ESTER SILVEIRA - FMRP ; FONTES, APARECIDA MARIA - FMRP ; SUARDI, GABRIELA APARECIDA MARCONDES - FMRP
- Unidade: FMRP
- Subjects: DOENÇAS METABÓLICAS; ENZIMAS; LINHAGEM CELULAR; DNA RECOMBINANTE
- Keywords: Gaucher disease; Codon optimization; Recombinant GCase; Lentiviral platform; Enzyme activity measurments
- Agências de fomento:
- Language: Português
- Imprenta:
- Publisher: Sociedade Brasileira de Genética (SBG)
- Publisher place: Ribeirão Preto
- Date published: 2024
- Source:
- Título: Resumos (e-Book )
- Conference titles: International Congress of the Brazilian Genetics Society
-
ABNT
SUARDI, Gabriela Aparecida Marcondes et al. Stable and cost-effective production of GCASE-OPT using a low MOI lentiviral approach for enzyme replacement therapy in gaucher disease: development of L20_HEF1A_GBA-OPT-R534H, a stable human cell line. 2024, Anais.. Ribeirão Preto: Sociedade Brasileira de Genética (SBG), 2024. Disponível em: https://www.sbg.org.br/admin/files/book/book_bcovOe2cEJzf.pdf. Acesso em: 27 jan. 2026. -
APA
Suardi, G. A. M., Wiezel, C. E. V., Tirapelli, D. P. da C., Ramos, E. S., Almeida, V. de, Siciliano, V., et al. (2024). Stable and cost-effective production of GCASE-OPT using a low MOI lentiviral approach for enzyme replacement therapy in gaucher disease: development of L20_HEF1A_GBA-OPT-R534H, a stable human cell line. In Resumos (e-Book ). Ribeirão Preto: Sociedade Brasileira de Genética (SBG). Recuperado de https://www.sbg.org.br/admin/files/book/book_bcovOe2cEJzf.pdf -
NLM
Suardi GAM, Wiezel CEV, Tirapelli DP da C, Ramos ES, Almeida V de, Siciliano V, Gerson S, Weiss R, Fontes AM. Stable and cost-effective production of GCASE-OPT using a low MOI lentiviral approach for enzyme replacement therapy in gaucher disease: development of L20_HEF1A_GBA-OPT-R534H, a stable human cell line [Internet]. Resumos (e-Book ). 2024 ;[citado 2026 jan. 27 ] Available from: https://www.sbg.org.br/admin/files/book/book_bcovOe2cEJzf.pdf -
Vancouver
Suardi GAM, Wiezel CEV, Tirapelli DP da C, Ramos ES, Almeida V de, Siciliano V, Gerson S, Weiss R, Fontes AM. Stable and cost-effective production of GCASE-OPT using a low MOI lentiviral approach for enzyme replacement therapy in gaucher disease: development of L20_HEF1A_GBA-OPT-R534H, a stable human cell line [Internet]. Resumos (e-Book ). 2024 ;[citado 2026 jan. 27 ] Available from: https://www.sbg.org.br/admin/files/book/book_bcovOe2cEJzf.pdf - Comparative analysis of lentiviral transduction between adherent and non-adherente hek 293T cells
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