In silico studies and biological evaluation of thiosemicarbazones as cruzain-targeting trypanocidal agents for Chagas disease (2026)
- Authors:
- USP affiliated authors: ANDRICOPULO, RENATA KROGH - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; DÖRING, THIAGO HENRIQUE - IFSC
- Unidade: IFSC
- DOI: 10.3390/pharmaceutics18010065
- Subjects: DOENÇA DE CHAGAS; PLANEJAMENTO DE FÁRMACOS
- Keywords: ADMET; Chagas disease; Cruzain inhibition; Molecular docking; Thiosemicarbazones
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Pharmaceutics
- ISSN: 1999-4923
- Volume/Número/Paginação/Ano: v. 18, n. 1, p. 65-1-65-14, Jan. 2026
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
MEIER, Lidiane et al. In silico studies and biological evaluation of thiosemicarbazones as cruzain-targeting trypanocidal agents for Chagas disease. Pharmaceutics, v. 18, n. Ja 2026, p. 65-1-65-14, 2026Tradução . . Disponível em: https://doi.org/10.3390/pharmaceutics18010065. Acesso em: 01 abr. 2026. -
APA
Meier, L., Melo Milena F. C. V. de,, Abreu, H. R., Oliveira, I. M. de, Sens, L., Döring, T. H., et al. (2026). In silico studies and biological evaluation of thiosemicarbazones as cruzain-targeting trypanocidal agents for Chagas disease. Pharmaceutics, 18( Ja 2026), 65-1-65-14. doi:10.3390/pharmaceutics18010065 -
NLM
Meier L, Melo Milena F. C. V. de, Abreu HR, Oliveira IM de, Sens L, Döring TH, Krogh R, Beatriz A, Andricopulo AD, Saba S, Oliveira AS de, Rafique J. In silico studies and biological evaluation of thiosemicarbazones as cruzain-targeting trypanocidal agents for Chagas disease [Internet]. Pharmaceutics. 2026 ; 18( Ja 2026): 65-1-65-14.[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/pharmaceutics18010065 -
Vancouver
Meier L, Melo Milena F. C. V. de, Abreu HR, Oliveira IM de, Sens L, Döring TH, Krogh R, Beatriz A, Andricopulo AD, Saba S, Oliveira AS de, Rafique J. In silico studies and biological evaluation of thiosemicarbazones as cruzain-targeting trypanocidal agents for Chagas disease [Internet]. Pharmaceutics. 2026 ; 18( Ja 2026): 65-1-65-14.[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/pharmaceutics18010065 - Design, synthesis, and in vitro evaluation of 4-(arylchalcogenyl)methyl)-1H-1,2,3-triazol-1-yl-menadione: exploring their potential against tuberculosis
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