Dona Flor and her two husbands: discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment (2025)
- Authors:
- Waitman, Karoline de Barros

- Martin, Holli Joi

- Carlos, Jorge Antonio Elias Godoy

- Braga, Rodolpho C.

- Souza, Vinicius Albuquerque Moreira de

- Melo Filho, Cleber Camilo de

- Hilscher, Sebastian

- Toledo, Mônica Franco Zannini Junqueira

- Tavares, Maurício Temotheo

- Schutkowski, Mike

- Sippl, Wolfgang

- Kronenberger, Thales

- Alves, Vinícius de Medeiros

- Parise Filho, Roberto

- Muratov, Eugene N.

- Costa-Lotufo, Letícia Veras

- Machado Neto, João Agostinho

- Waitman, Karoline de Barros
- USP affiliated authors: TOLEDO, MONICA FRANCO ZANNINI JUNQUEIRA - FCF ; LOTUFO, LETICIA VERAS COSTA - ICB ; MACHADO NETO, JOÃO AGOSTINHO - ICB ; PARISE FILHO, ROBERTO - FCF ; SOUZA, VINICIUS ALBUQUERQUE MOREIRA DE - FCF ; WAITMAN, KAROLINE DE BARROS - FCF ; CARLOS, JORGE ANTONIO ELIAS GODOY - ICB
- Unidades: FCF; ICB
- DOI: 10.1016/j.compbiomed.2025.110990
- Subjects: FARMACOLOGIA; LEUCEMIA MIELOIDE AGUDA; NEOPLASIAS POR TIPO HISTOLÓGICO; CÉLULAS MIELOIDES; ANTINEOPLÁSICOS; CÉLULAS CULTIVADAS DE TUMOR; CÉLULAS DA MEDULA ÓSSEA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Computers in Biology and Medicine
- ISSN: 1879-0534
- Volume/Número/Paginação/Ano: v. 197, part. A, art. 110990, 16 p., 2025
- Status:
- Nenhuma versão em acesso aberto identificada
-
ABNT
WAITMAN, Karoline de Barros et al. Dona Flor and her two husbands: discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment. Computers in Biology and Medicine, v. 197, p. 16 , 2025Tradução . . Disponível em: https://doi.org/10.1016/j.compbiomed.2025.110990. Acesso em: 31 mar. 2026. -
APA
Waitman, K. de B., Martin, H. J., Carlos, J. A. E. G., Braga, R. C., Souza, V. A. M. de, Melo Filho, C. C. de, et al. (2025). Dona Flor and her two husbands: discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment. Computers in Biology and Medicine, 197, 16 . doi:10.1016/j.compbiomed.2025.110990 -
NLM
Waitman K de B, Martin HJ, Carlos JAEG, Braga RC, Souza VAM de, Melo Filho CC de, Hilscher S, Toledo MFZJ, Tavares MT, Schutkowski M, Sippl W, Kronenberger T, Alves V de M, Parise Filho R, Muratov EN, Costa-Lotufo LV, Machado Neto JA. Dona Flor and her two husbands: discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment [Internet]. Computers in Biology and Medicine. 2025 ; 197 16 .[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.compbiomed.2025.110990 -
Vancouver
Waitman K de B, Martin HJ, Carlos JAEG, Braga RC, Souza VAM de, Melo Filho CC de, Hilscher S, Toledo MFZJ, Tavares MT, Schutkowski M, Sippl W, Kronenberger T, Alves V de M, Parise Filho R, Muratov EN, Costa-Lotufo LV, Machado Neto JA. Dona Flor and her two husbands: discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment [Internet]. Computers in Biology and Medicine. 2025 ; 197 16 .[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.compbiomed.2025.110990 - Synthesis and biological evaluation of hybrid inhibitors for the treatment of hematologic malignancies
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- HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
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