Anti-Trypanosoma cruzi activity, mutagenicity, hepatocytotoxicity and nitroreductase enzyme evaluation of 3-nitrotriazole, 2-nitroimidazole and triazole derivatives (2023)
- Authors:
- Menozzi, Cheyene Almeida Celestino
- França, Rodolfo Rodrigo Florido
- Luccas, Pedro Henrique
- Baptista, Mayara dos Santos
- Fernandes, Tácio Vinício Amorim
- Hoelz, Lucas Villas Bôas
- Sales Junior, Policarpo Ademar
- Murta, Silvane Maria Fonseca
- Romanha, Álvaro
- Galvão, Bárbara Verena Dias
- Macedo, Marcela de Oliveira
- Goldstein, Alana da Cunha
- Araujo-Lima, Carlos Fernando
- Felzenszwalb, Israel
- Nonato, Maria Cristina
- Castelo Branco, Frederico Silva
- Boechat, Núbia
- Autor USP: NONATO, MARIA CRISTINA - FCFRP
- Unidade: FCFRP
- DOI: 10.3390/molecules28227461
- Subjects: DOENÇA DE CHAGAS; FARMACOTERAPIA; MUTAGÊNICOS; TRYPANOSOMA CRUZI; COMPOSTOS HETEROCÍCLICOS
- Keywords: Chagas disease; Azole; Nitroreductase; Triazole; Imidazole; Heterocycle
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
MENOZZI, Cheyene Almeida Celestino et al. Anti-Trypanosoma cruzi activity, mutagenicity, hepatocytotoxicity and nitroreductase enzyme evaluation of 3-nitrotriazole, 2-nitroimidazole and triazole derivatives. Molecules, v. 28, n. 22, p. 1-20, 2023Tradução . . Disponível em: https://doi.org/10.3390/molecules28227461. Acesso em: 03 dez. 2025. -
APA
Menozzi, C. A. C., França, R. R. F., Luccas, P. H., Baptista, M. dos S., Fernandes, T. V. A., Hoelz, L. V. B., et al. (2023). Anti-Trypanosoma cruzi activity, mutagenicity, hepatocytotoxicity and nitroreductase enzyme evaluation of 3-nitrotriazole, 2-nitroimidazole and triazole derivatives. Molecules, 28( 22), 1-20. doi:10.3390/molecules28227461 -
NLM
Menozzi CAC, França RRF, Luccas PH, Baptista M dos S, Fernandes TVA, Hoelz LVB, Sales Junior PA, Murta SMF, Romanha Á, Galvão BVD, Macedo M de O, Goldstein A da C, Araujo-Lima CF, Felzenszwalb I, Nonato MC, Castelo Branco FS, Boechat N. Anti-Trypanosoma cruzi activity, mutagenicity, hepatocytotoxicity and nitroreductase enzyme evaluation of 3-nitrotriazole, 2-nitroimidazole and triazole derivatives [Internet]. Molecules. 2023 ; 28( 22): 1-20.[citado 2025 dez. 03 ] Available from: https://doi.org/10.3390/molecules28227461 -
Vancouver
Menozzi CAC, França RRF, Luccas PH, Baptista M dos S, Fernandes TVA, Hoelz LVB, Sales Junior PA, Murta SMF, Romanha Á, Galvão BVD, Macedo M de O, Goldstein A da C, Araujo-Lima CF, Felzenszwalb I, Nonato MC, Castelo Branco FS, Boechat N. Anti-Trypanosoma cruzi activity, mutagenicity, hepatocytotoxicity and nitroreductase enzyme evaluation of 3-nitrotriazole, 2-nitroimidazole and triazole derivatives [Internet]. Molecules. 2023 ; 28( 22): 1-20.[citado 2025 dez. 03 ] Available from: https://doi.org/10.3390/molecules28227461 - Heterologous expression and kinetic analysis of recombinant fumarate hydratase from Leishmania major
- Functional characterization of Leishmania major dihydroorotate dehydrogenase
- Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain
- Preliminary structural characterization of Trypanosoma cruzi fumarate hydratase
- Crystal structure of fumarate hydratase from Leishmania major
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- The dihydroorotate dehydrogenases: Past and present
- Clonning, expression and purification of Leishmania major fumarate hydratase
- Molecular cloning, expression and purification of cabohydrate recognition domains (CRDs) from human galectin-4
- Preliminary biochemical characterization of dihydroorotate dehydrogenase from Xylella fastidiosa strain 9A5C
Informações sobre o DOI: 10.3390/molecules28227461 (Fonte: oaDOI API)
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