Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae (2025)
- Authors:
- USP affiliated authors: FERREIRA, LEONARDO LUIZ GOMES - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; SILVA, JOÃO VICTOR DA SILVA E - IFSC ; DÖRING, THIAGO HENRIQUE - IFSC
- Unidade: IFSC
- DOI: 10.3390/ph18070997
- Subjects: PLANEJAMENTO DE FÁRMACOS; TOXOCARA CANIS; RESISTÊNCIA MICROBIANA ÀS DROGAS
- Keywords: Toxocara canis; H1 antihistamine; β-tubulin; Density functional theory; Molecular docking
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Pharmaceuticals
- ISSN: 1424-8247
- Volume/Número/Paginação/Ano: v. 18, n. 7, p. 997-1-997-14 + supplementary materials, July 2025
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
SILVA, Tais C. et al. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae. Pharmaceuticals, v. 18, n. 7, p. 997-1-997-14 + supplementary materials, 2025Tradução . . Disponível em: https://doi.org/10.3390/ph18070997. Acesso em: 29 dez. 2025. -
APA
Silva, T. C., Silva, J. G., Amaro, M. C., Silva-Silva, J. V., Döring, T. H., Ferreira, L. L. G., et al. (2025). Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae. Pharmaceuticals, 18( 7), 997-1-997-14 + supplementary materials. doi:10.3390/ph18070997 -
NLM
Silva TC, Silva JG, Amaro MC, Silva-Silva JV, Döring TH, Ferreira LLG, Andricopulo AD, Moraes J de. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae [Internet]. Pharmaceuticals. 2025 ; 18( 7): 997-1-997-14 + supplementary materials.[citado 2025 dez. 29 ] Available from: https://doi.org/10.3390/ph18070997 -
Vancouver
Silva TC, Silva JG, Amaro MC, Silva-Silva JV, Döring TH, Ferreira LLG, Andricopulo AD, Moraes J de. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae [Internet]. Pharmaceuticals. 2025 ; 18( 7): 997-1-997-14 + supplementary materials.[citado 2025 dez. 29 ] Available from: https://doi.org/10.3390/ph18070997 - Aflavinine alkaloids from Aspergillus sp.: antibacterial activity and inosine 5’-monophosphate dehydrogenase (IMPDH) as a potential target in bacillus subtilis
- Assessment of 1,2,3-triazole-selenide hybrids as potential trypanothione reductase inhibitors: implications for trypanocidal activity
- Molecular docking to predict the interaction of piperine with the enzyme acetylcholinesterase for Alzheimer's disease treatment
- Computational studies of new chemotherapeutic agents derived from natural products for the treatment of neglected tropical diseases (NTDs)
- Planejamento de novos agentes quimioterápicos para o tratamento da doença de Chagas
- Leishmanicidal benzodiazepines as DHFR-TS inhibitors: in vitro and in silico analysis
- Neglected tropical diseases: a chemoinformatics approach for the use of biodiversity in anti-trypanosomatid drug discovery
- Design, synthesis, and in vitro evaluation of 4-(arylchalcogenyl)methyl)-1H-1,2,3-triazol-1-yl-menadione: exploring their potential against tuberculosis
- Novel brominated vinylic fatty acids effectively inhibit the leishmania topoisomerase IB enzyme mediated by halogen bond formation
- 3D QSAR studies for a series of Trypanosoma cruzi dehydrogenase inhibitors
Informações sobre o DOI: 10.3390/ph18070997 (Fonte: oaDOI API)
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
| PROD037313_3257457.pdf | Direct link |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
