Artigo de periodico

Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae (2025)

• Authors:
  • Silva, Tais C.
  • Silva, Julia Godoy
  • Amaro, Monique C.
  • Silva-Silva, João Victor
  • Döring, Thiago Henrique
  • Ferreira, Leonardo Luiz Gomes
  • Andricopulo, Adriano Defini
  • Moraes, Josué de
• USP affiliated authors: FERREIRA, LEONARDO LUIZ GOMES - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; SILVA, JOÃO VICTOR DA SILVA E - IFSC ; DÖRING, THIAGO HENRIQUE - IFSC
• Unidade: IFSC
• DOI: 10.3390/ph18070997
• Subjects: PLANEJAMENTO DE FÁRMACOS; TOXOCARA CANIS; RESISTÊNCIA MICROBIANA ÀS DROGAS
• Keywords: Toxocara canis; H1 antihistamine; β-tubulin; Density functional theory; Molecular docking
• Agências de fomento:
  • Financiamento FAPESP
  • Financiamento CNPq
  • Financiamento CAPES
• Language: Inglês
• Imprenta:
  • Publisher place: Basel
  • Date published: 2025
• Source:
  • Título: Pharmaceuticals
  • ISSN: 1424-8247
  • Volume/Número/Paginação/Ano: v. 18, n. 7, p. 997-1-997-14 + supplementary materials, July 2025


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• ABNT

  SILVA, Tais C. et al. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae. Pharmaceuticals, v. 18, n. 7, p. 997-1-997-14 + supplementary materials, 2025Tradução . . Disponível em: https://doi.org/10.3390/ph18070997. Acesso em: 31 mar. 2026.

• APA

  Silva, T. C., Silva, J. G., Amaro, M. C., Silva-Silva, J. V., Döring, T. H., Ferreira, L. L. G., et al. (2025). Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae. Pharmaceuticals, 18( 7), 997-1-997-14 + supplementary materials. doi:10.3390/ph18070997

• NLM

  Silva TC, Silva JG, Amaro MC, Silva-Silva JV, Döring TH, Ferreira LLG, Andricopulo AD, Moraes J de. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae [Internet]. Pharmaceuticals. 2025 ; 18( 7): 997-1-997-14 + supplementary materials.[citado 2026 mar. 31 ] Available from: https://doi.org/10.3390/ph18070997

• Vancouver

  Silva TC, Silva JG, Amaro MC, Silva-Silva JV, Döring TH, Ferreira LLG, Andricopulo AD, Moraes J de. Phenotypic screening of H1-antihistamines identifies promethazine and rupatadine as active compounds against Toxocara canis infective larvae [Internet]. Pharmaceuticals. 2025 ; 18( 7): 997-1-997-14 + supplementary materials.[citado 2026 mar. 31 ] Available from: https://doi.org/10.3390/ph18070997

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