MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT (2025)
- Authors:
- Ninni, Andrea
- Zaccaria, Fabio
- Sciarretta, Francesca
- Silveira, Loreana Sanches
- Carotti, Simone
- Nevi, Lorenzo
- Grumati, Paolo
- Patel, Satish
- Carrera, Giulia
- Sgambato, Alessandro
- Lucchetti, Donatella
- Colella, Filomena
- Severi, Ilenia
- Senzacqua, Martina
- Giordano, Antonio
- Bernardini, Sergio
- Biagio, Claudia Di
- Tortolici, Flavia
- Rizzo, Giuseppe
- Cochain, Clément
- Chiurchiù, Valerio
- Ivanov, Stoyan
- Zhou, Beiyan
- Williams, Jesse W.
- Savage, David B.
- Aquilano, Katia
- Lettieri-Barbato, Danielle
- Rosa Neto, José Cesar
- USP affiliated authors: ROSA NETO, JOSÉ CESAR - ICB ; SILVEIRA, LOREANA SANCHES - ICB
- Unidade: ICB
- DOI: 10.1038/s41467-025-60295-2
- Subjects: BIOLOGIA CELULAR; TECIDO ADIPOSO; LIPÍDEOS; MACRÓFAGOS; OBESIDADE; RNA; EXPRESSÃO GÊNICA; TERMOGÊNESE; GORDURAS NA DIETA; CAMUNDONGOS
- Agências de fomento:
- Financiamento Biomedical Research Centre e NIHR Rare Disease Translational Research Collaboration
- Financiamento Instituto Nacional de Pesquisa em Saúde (NIHR)
- Financiamento pela FAPESP
- Financiamento pelo projeto MUR-PNRR M4C21.3 PE6 PE00000019 Heal Italia
- Financiamento pela União Europeia - Next Generation EU
- Language: Inglês
- Imprenta:
- Source:
- Título: Nature Communications
- ISSN: 2041-1723
- Volume/Número/Paginação/Ano: v. 16, n. 1, art. 5063, 16 p., 2025
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
NINNI, Andrea et al. MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT. Nature Communications, v. 16, n. 1, p. 16 , 2025Tradução . . Disponível em: https://doi.org/10.1038/s41467-025-60295-2. Acesso em: 14 fev. 2026. -
APA
Ninni, A., Zaccaria, F., Sciarretta, F., Silveira, L. S., Carotti, S., Nevi, L., et al. (2025). MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT. Nature Communications, 16( 1), 16 . doi:10.1038/s41467-025-60295-2 -
NLM
Ninni A, Zaccaria F, Sciarretta F, Silveira LS, Carotti S, Nevi L, Grumati P, Patel S, Carrera G, Sgambato A, Lucchetti D, Colella F, Severi I, Senzacqua M, Giordano A, Bernardini S, Biagio CD, Tortolici F, Rizzo G, Cochain C, Chiurchiù V, Ivanov S, Zhou B, Williams JW, Savage DB, Aquilano K, Lettieri-Barbato D, Rosa Neto JC. MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT [Internet]. Nature Communications. 2025 ; 16( 1): 16 .[citado 2026 fev. 14 ] Available from: https://doi.org/10.1038/s41467-025-60295-2 -
Vancouver
Ninni A, Zaccaria F, Sciarretta F, Silveira LS, Carotti S, Nevi L, Grumati P, Patel S, Carrera G, Sgambato A, Lucchetti D, Colella F, Severi I, Senzacqua M, Giordano A, Bernardini S, Biagio CD, Tortolici F, Rizzo G, Cochain C, Chiurchiù V, Ivanov S, Zhou B, Williams JW, Savage DB, Aquilano K, Lettieri-Barbato D, Rosa Neto JC. MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT [Internet]. Nature Communications. 2025 ; 16( 1): 16 .[citado 2026 fev. 14 ] Available from: https://doi.org/10.1038/s41467-025-60295-2 - Moderate aerobic exercise-induced cytokines changes are disturbed in PPARα knockout mice
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Informações sobre o DOI: 10.1038/s41467-025-60295-2 (Fonte: oaDOI API)
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