Artigo de periodico

Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia (2025)

• Authors:
  • Bortolin, Raul Hernandes
  • Leite, Felipe de Souza
  • Luchessi, André Ducati
  • Esposito, Joyce
  • Barbosa, Igor Neves
  • Freitas, Renata Caroline Costa de
  • Sonawane, Abhijeet Rajendra
  • Singh, Sasha Anna
  • Aikawa, Elena
  • Silva, Kayque Alves Telles
  • Hirata, Thiago Dominguez Crespo
  • Neta, Antonia Pereira Rosa
  • Goulart, Ernesto
  • Caires-Junior, Luiz Carlos
  • Martins, Thais Maria da Mata
  • Semedo, Patrícia
  • Moreira, Danielle de Paula
  • Naslavsky, Michel
  • Faludi, André Arpad
  • Gonçalves, Rodrigo Marques
  • Hirata, Mario Hiroyuki
  • Malaquias, Vanessa Barbosa
  • Ferreira, Glaucio Monteiro
  • Pu, William T
  • Hirata, Rosario Dominguez Crespo
• USP affiliated authors: HIRATA, THIAGO DOMINGUEZ CRESPO - FCF ; NASLAVSKY, MICHEL SATYA - IB ; HIRATA, MARIO HIROYUKI - FCF ; FERREIRA, GLAUCIO MONTEIRO - FCF ; HIRATA, ROSARIO DOMINGUEZ CRESPO - FCF ; BARBOSA, IGOR NEVES - IB ; SILVA, KAYQUE ALVES TELLES - IB ; MALAQUIAS, VANESSA BARBOSA - FCF
• Unidades: FCF; IB
• DOI: 10.1016/j.tox.2025.154159
• Subjects: ESTATINAS; CÉLULAS MUSCULARES; PROTEÔMICA
• Agências de fomento:
  • Financiamento FAPESP
  • Financiamento CNPq
  • Financiamento CAPES
  • Financiamento CEPID-FAPESP
  • Financiamento INCT
  • Financiamento NIH
  • Financiamento American Heart Association
• Language: Inglês
• Imprenta:
  • Publisher place: Clare
  • Date published: 2025
• Source:
  • Título: Toxicology
  • ISSN: 0300-483X
  • Volume/Número/Paginação/Ano: v. 515, p. 1-16 art. 154159, 2025

Informações sobre o DOI: 10.1016/j.tox.2025.154159 (Fonte: oaDOI API)
• Este periódico é de acesso aberto
• Este artigo NÃO é de acesso aberto
  

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• ABNT

  BORTOLIN, Raul Hernandes et al. Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia. Toxicology, v. 515, p. 1-16 art. 154159, 2025Tradução . . Disponível em: https://dx.doi.org/10.1016/j.tox.2025.154159. Acesso em: 10 fev. 2026.

• APA

  Bortolin, R. H., Leite, F. de S., Luchessi, A. D., Esposito, J., Barbosa, I. N., Freitas, R. C. C. de, et al. (2025). Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia. Toxicology, 515, 1-16 art. 154159. doi:10.1016/j.tox.2025.154159

• NLM

  Bortolin RH, Leite F de S, Luchessi AD, Esposito J, Barbosa IN, Freitas RCC de, Sonawane AR, Singh SA, Aikawa E, Silva KAT, Hirata TDC, Neta APR, Goulart E, Caires-Junior LC, Martins TM da M, Semedo P, Moreira D de P, Naslavsky M, Faludi AA, Gonçalves RM, Hirata MH, Malaquias VB, Ferreira GM, Pu WT, Hirata RDC. Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia [Internet]. Toxicology. 2025 ; 515 1-16 art. 154159.[citado 2026 fev. 10 ] Available from: https://dx.doi.org/10.1016/j.tox.2025.154159

• Vancouver

  Bortolin RH, Leite F de S, Luchessi AD, Esposito J, Barbosa IN, Freitas RCC de, Sonawane AR, Singh SA, Aikawa E, Silva KAT, Hirata TDC, Neta APR, Goulart E, Caires-Junior LC, Martins TM da M, Semedo P, Moreira D de P, Naslavsky M, Faludi AA, Gonçalves RM, Hirata MH, Malaquias VB, Ferreira GM, Pu WT, Hirata RDC. Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia [Internet]. Toxicology. 2025 ; 515 1-16 art. 154159.[citado 2026 fev. 10 ] Available from: https://dx.doi.org/10.1016/j.tox.2025.154159

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