Inhibition of MEK1/2 signaling pathway limits M2 macrophage polarization and interferes in the dental socket repair process in mice (2025)
- Authors:
- USP affiliated authors: ORTIZ, RAFAEL CARNEIRO - FOB ; PEGORARO, CAMILA DE OLIVEIRA RODINI - FOB ; GARLET, GUSTAVO POMPERMAIER - FOB ; FONSECA, ANGÉLICA CRISTINA - HRAC ; MACHADO, PRISCILA MARIA COLAVITE - FOB ; AZEVEDO, MICHELLE DE CAMPOS SORIANI - FOB ; PASSADORI, DANIELA CARIGNATTO - FOB ; MELCHIADES, JESSICA LIMA - FOB
- Unidades: FOB; HRAC
- DOI: 10.3390/biology14020107
- Subjects: IMUNOLOGIA; REPARO ÓSSEO; PROTEÍNAS QUINASES
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
FONSECA, Angélica Cristina et al. Inhibition of MEK1/2 signaling pathway limits M2 macrophage polarization and interferes in the dental socket repair process in mice. Biology, v. 14, 2025Tradução . . Disponível em: https://doi.org/10.3390/biology14020107. Acesso em: 01 abr. 2026. -
APA
Fonseca, A. C., Colavite, P. M., Azevedo, M. de C. S., Passadori, D. C., Melchiades, J. L., Ortiz, R. C., et al. (2025). Inhibition of MEK1/2 signaling pathway limits M2 macrophage polarization and interferes in the dental socket repair process in mice. Biology, 14. doi:10.3390/biology14020107 -
NLM
Fonseca AC, Colavite PM, Azevedo M de CS, Passadori DC, Melchiades JL, Ortiz RC, Rodini C de O, Trombone APF, Garlet GP. Inhibition of MEK1/2 signaling pathway limits M2 macrophage polarization and interferes in the dental socket repair process in mice [Internet]. Biology. 2025 ; 14[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/biology14020107 -
Vancouver
Fonseca AC, Colavite PM, Azevedo M de CS, Passadori DC, Melchiades JL, Ortiz RC, Rodini C de O, Trombone APF, Garlet GP. Inhibition of MEK1/2 signaling pathway limits M2 macrophage polarization and interferes in the dental socket repair process in mice [Internet]. Biology. 2025 ; 14[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/biology14020107 - Intermediate and transitory inflammation mediate proper alveolar bone healing outcome in contrast to extreme low/high responses: : evidence from mice strains selected for distinct inflammatory phenotypes
- FTY720 administration results in a M2 associated immunoregulatory effect that positively influences the outcome of alveolar bone repair outcome in mice
- Vasoactive intestinal peptide immunoregulatory role at the periapex: associative and mechanistic evidences from human and experimental periapical lesions
- Sildenafil reduces bisphosphonate-induced jaw osteonecrosis in rats
- Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms
- TBX21-1993T/C polymorphism association with Th1 and Th17 response at periapex and with periapical lesions development risk
- Macrophage polarization and alveolar bone healing outcome: despite a significant M2 polarizing effect, VIP and PACAP treatments present a minor impact in alveolar bone healing in homeostatic conditions
- Possible role of ALDH1 and CD44 in lip carcinogenesis
- Influence of zoledronic acid and low-intensity laser on collagen fibers during the bone repair process
- B lymphocytes deficiency results in altered immune response and increased susceptibility to mycobacterium leprae in a murine leprosy model
Informações sobre a disponibilidade de versões do artigo em acesso aberto coletadas automaticamente via oaDOI API (Unpaywall).
Por se tratar de integração com serviço externo, podem existir diferentes versões do trabalho (como preprints ou postprints), que podem diferir da versão publicada.
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
| 3238239.pdf | Direct link |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
