3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: validation as a molecular target, proposal of a novel catalytic mechanism, and inhibitors in preclinical and clinical trials (2024)
- Authors:
- USP affiliated authors: SOUZA, ROBSON FRANCISCO DE - ICB ; CARVALHO, CRISTIANE RODRIGUES GUZZO - ICB ; AMORIM, VITOR MARTINS DE FREITAS - ICB ; FERRARI, ANIELLE SALVIANO DE ALMEIDA - ICB ; MERIGHI, DAVI GABRIEL SALUSTIANO - ICB ; SOUZA, ANACLETO SILVA DE - ICB
- Unidade: ICB
- DOI: 10.3390/v16060844
- Subjects: MICROBIOLOGIA; CATÁLISE; ANTIVIRAIS; COVID-19; CORONAVIRUS; INIBIDORES DE ENZIMAS
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Viruses ISSN:1999-4915
- ISSN: 1999-4915
- Volume/Número/Paginação/Ano: v. 16, n. 6, art. 844, 22 p., 2024
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
AMORIM, Vitor Martins de Freitas et al. 3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: validation as a molecular target, proposal of a novel catalytic mechanism, and inhibitors in preclinical and clinical trials. Viruses ISSN:1999-4915, v. 16, n. 6, p. 22 , 2024Tradução . . Disponível em: https://doi.org/10.3390/v16060844. Acesso em: 01 abr. 2026. -
APA
Amorim, V. M. de F., Soares, E. P., Ferrari, A. S. de A., Merighi, D. G. S., Souza, A. S. de, Souza, R. F. de, & Guzzo, C. R. (2024). 3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: validation as a molecular target, proposal of a novel catalytic mechanism, and inhibitors in preclinical and clinical trials. Viruses ISSN:1999-4915, 16( 6), 22 . doi:10.3390/v16060844 -
NLM
Amorim VM de F, Soares EP, Ferrari AS de A, Merighi DGS, Souza AS de, Souza RF de, Guzzo CR. 3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: validation as a molecular target, proposal of a novel catalytic mechanism, and inhibitors in preclinical and clinical trials [Internet]. Viruses ISSN:1999-4915. 2024 ; 16( 6): 22 .[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/v16060844 -
Vancouver
Amorim VM de F, Soares EP, Ferrari AS de A, Merighi DGS, Souza AS de, Souza RF de, Guzzo CR. 3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: validation as a molecular target, proposal of a novel catalytic mechanism, and inhibitors in preclinical and clinical trials [Internet]. Viruses ISSN:1999-4915. 2024 ; 16( 6): 22 .[citado 2026 abr. 01 ] Available from: https://doi.org/10.3390/v16060844 - Molecular dynamics simulations of the spike trimeric ectodomain of the SARS-CoV-2 Omicron variant: structural relationships with infectivity, evasion to immune system and transmissibility
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