Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T. cruzi infected rats (2022)
- Authors:
- USP affiliated authors: MUNIZ, VÂNIA BRAZÃO - EERP ; TIRAPELLI, CARLOS RENATO - EERP ; PASSAGLIA, RITA DE CASSIA ALEIXO TOSTES - FMRP ; PRADO JUNIOR, JOSE CLOVIS DO - FCFRP ; DUARTE, ANDRESSA - FMRP ; GOULART, AMANDA - FCFRP ; OLIVEIRA, PEDRO ALEXANDRE SAMPAIO - FCFRP ; SILVA, CARLA BRIGAGÃO PACHECO DA - FMRP ; COSTA, RAFAEL MENEZES DA - FMRP
- Unidades: EERP; FMRP; FCFRP
- DOI: 10.1016/j.exger.2022.111895
- Subjects: ANTIOXIDANTES; DOENÇA DE CHAGAS; PERÓXIDO DE HIDROGÊNIO; MELATONINA; ESTRESSE OXIDATIVO
- Keywords: Aging; Cytokines; Melatonin; Nrf2 and NF-κB regulation; Trypanosoma cruzi.
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Philadelphia
- Date published: 2022
- Source:
- Título: Experimental Gerontology
- ISSN: 0531-5565
- Volume/Número/Paginação/Ano: v. 167, art. 111895, p. 1-9, 2022
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
BRAZÃO, Vânia et al. Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T. cruzi infected rats. Experimental Gerontology, v. 167, p. 1-9, 2022Tradução . . Disponível em: https://doi.org/10.1016/j.exger.2022.111895. Acesso em: 13 fev. 2026. -
APA
Brazão, V., Colato, R. P., Santello, F. H., Duarte, A., Goulart, A., Oliveira, P. A. S., et al. (2022). Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T. cruzi infected rats. Experimental Gerontology, 167, 1-9. doi:10.1016/j.exger.2022.111895 -
NLM
Brazão V, Colato RP, Santello FH, Duarte A, Goulart A, Oliveira PAS, Silva CBP da, Tirapelli CR, Costa RM da, Tostes R de CA, Prado Júnior JC do. Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T. cruzi infected rats [Internet]. Experimental Gerontology. 2022 ; 167 1-9.[citado 2026 fev. 13 ] Available from: https://doi.org/10.1016/j.exger.2022.111895 -
Vancouver
Brazão V, Colato RP, Santello FH, Duarte A, Goulart A, Oliveira PAS, Silva CBP da, Tirapelli CR, Costa RM da, Tostes R de CA, Prado Júnior JC do. Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T. cruzi infected rats [Internet]. Experimental Gerontology. 2022 ; 167 1-9.[citado 2026 fev. 13 ] Available from: https://doi.org/10.1016/j.exger.2022.111895 - Effects of melatonin on thymic and oxidative stress dysfunctions during Trypanosoma cruzi infection
- Melatonin down-regulates steroidal hormones, thymocyte apoptosis and inflammatory cytokines in middle-aged T. cruzi infected rats
- Estudo das alterações tímicas relacionadas com a idade durante a infecção por Trypanosoma cruzi
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- T. cruzi infection among aged rats: melatonin as a promising therapeutic molecule
- Melatonin: antioxidant and modulatory properties in age‐related changes during Trypanosoma cruzi infection
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- Estrone-mediated lowering of ROS and NOX4 improves endothelial function in ovariectomized wistar rats
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Informações sobre o DOI: 10.1016/j.exger.2022.111895 (Fonte: oaDOI API)
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