Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol (2021)
- Authors:
- USP affiliated authors: PAULA, GUSTAVO HENRIQUE OLIVEIRA DE - FMRP ; PINHEIRO, LUCAS CÉZAR - EERP ; GARCIA, WAYNICE NEIVA DE PAULA - FMRP ; GARCIA, LUIS VICENTE - FMRP ; LACCHINI, RICCARDO - EERP ; SANTOS, JOSE EDUARDO TANUS DOS - FMRP ; FERREIRA, GRAZIELE CRISTINA - FMRP
- Unidades: FMRP; EERP
- DOI: 10.1111/bcpt.13691
- Subjects: ANESTÉSICOS INTRAVENOSOS; ESTUDOS TRANSVERSAIS; GENÓTIPOS; HAPLOTIPOS; HIPOTENSÃO; ÓXIDO NÍTRICO
- Keywords: Anaesthesia; Blood pressure; Nitric oxide; Protein kinase C; Single nucleotide polymorphisms
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Chichester
- Date published: 2021
- Source:
- Título: Basic & Clinical Pharmacology & Toxicology
- ISSN: 1742-7835
- Volume/Número/Paginação/Ano: v. 130, n. 2, p. 277-287, 2022
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
PAULA, Gustavo Henrique Oliveira de et al. Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol. Basic & Clinical Pharmacology & Toxicology, v. 130, n. 2, p. 277-287, 2021Tradução . . Disponível em: https://doi.org/10.1111/bcpt.13691. Acesso em: 04 ago. 2025. -
APA
Paula, G. H. O. de, Pereira, D. A., Pinheiro, L. C., Ferreira, G. C., Garcia, W. N. de P., Garcia, L. V., et al. (2021). Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol. Basic & Clinical Pharmacology & Toxicology, 130( 2), 277-287. doi:10.1111/bcpt.13691 -
NLM
Paula GHO de, Pereira DA, Pinheiro LC, Ferreira GC, Garcia WN de P, Garcia LV, Lacchini R, Luizon MR, Tanus-Santos JE. Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol [Internet]. Basic & Clinical Pharmacology & Toxicology. 2021 ; 130( 2): 277-287.[citado 2025 ago. 04 ] Available from: https://doi.org/10.1111/bcpt.13691 -
Vancouver
Paula GHO de, Pereira DA, Pinheiro LC, Ferreira GC, Garcia WN de P, Garcia LV, Lacchini R, Luizon MR, Tanus-Santos JE. Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol [Internet]. Basic & Clinical Pharmacology & Toxicology. 2021 ; 130( 2): 277-287.[citado 2025 ago. 04 ] Available from: https://doi.org/10.1111/bcpt.13691 - Antioxidant tempol modulates the increases in tissue nitric oxide metabolites concentrations after oral nitrite administration
- TRPA1 polymorphisms modify the hypotensive responses to propofol with no change in nitrite or nitrate levels
- Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability
- Endothelial nitric oxide synthase polymorphisms affect the changes in blood pressure and nitric oxide bioavailability induced by propofol
- Mechanisms impairing blood pressure responses to nitrite and nitrate
- Antiseptic mouthwash inhibits antihypertensive and vascular protective effects of L-arginine
- Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production
- Lidocaine combined with magnesium sulfate preserved hemodynamic stability during general anesthesia without prolonging neuromuscular blockade: a randomized, double-blind, controlled trial
- A comprehensive time course study of tissue nitric oxide metabolites concentrations after oral nitrite administration
- Oral nitrite treatment increases S-nitrosylation of vascular protein kinase C and attenuates the responses to angiotensin II
Informações sobre o DOI: 10.1111/bcpt.13691 (Fonte: oaDOI API)
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