Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni (2021)
- Authors:
- USP affiliated authors: EMERY, FLAVIO DA SILVA - FCFRP ; NONATO, MARIA CRISTINA - FCFRP ; ZAPATA, LUANA CARLOS CAMPISANO - FCFRP ; MORI, RENAN MININ DE - FCFRP
- Unidade: FCFRP
- DOI: 10.1111/febs.15367
- Subjects: SCHISTOSOMA MANSONI; ESQUISTOSSOMOSE; FÁRMACOS; ANTI-HELMÍNTICOS
- Keywords: Crystal structure; Dihydroorotate dehydrogenase; Inhibition; Schistosoma mansoni; Schistosomiasis
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: West Sussex
- Date published: 2021
- Source:
- Título: The FEBS Journal
- ISSN: 1742-464X
- Volume/Número/Paginação/Ano: v. 288, n. 3, p. 930-944, 2021
- Status:
- Artigo possui acesso gratuito no site do editor (Bronze Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
MORI, Renan Minin de et al. Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni. The FEBS Journal, v. 288, n. 3, p. 930-944, 2021Tradução . . Disponível em: https://doi.org/10.1111/febs.15367. Acesso em: 02 abr. 2026. -
APA
Mori, R. M. de, Aleixo, M. A. A., Zapata, L. C. C., Calil, F. A., Emery, F. da S., & Nonato, M. C. (2021). Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni. The FEBS Journal, 288( 3), 930-944. doi:10.1111/febs.15367 -
NLM
Mori RM de, Aleixo MAA, Zapata LCC, Calil FA, Emery F da S, Nonato MC. Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni [Internet]. The FEBS Journal. 2021 ; 288( 3): 930-944.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1111/febs.15367 -
Vancouver
Mori RM de, Aleixo MAA, Zapata LCC, Calil FA, Emery F da S, Nonato MC. Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni [Internet]. The FEBS Journal. 2021 ; 288( 3): 930-944.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1111/febs.15367 - Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase
- Introducing CRAFT: the Center for Research and Advancement in Fragments and molecular Targets
- Hot spots identification and molecular fragment screening as innovative approaches to development Leishmania major diidroorotate dehydrogenase inhibitors
- DHODH hot spots: an underexplored source to guide drug development efforts
- Fragment screening against Schistosoma mansoni dihydroorotate dehydrogenase: a modern approach for drug discovery
- The antileishmanial activity of new semisynthetic naphthothiazols
- New semisynthetic naphtothiazols as leishmanicidal coumponds
- Beyond publishing. [Editorial]: introducing Interviews with authors
- A review of the synthetic strategies for the development of BODIPY dyes for conjugation with proteins
- On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by clik chemistry reactions
Informações sobre a disponibilidade de versões do artigo em acesso aberto coletadas automaticamente via oaDOI API (Unpaywall).
Por se tratar de integração com serviço externo, podem existir diferentes versões do trabalho (como preprints ou postprints), que podem diferir da versão publicada.
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
 |
003130256.pdf |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
