Drug repurposing in chagas disease: chloroquine potentiates benznidazole activity against Trypanosoma cruzi In vitro and in vivo (2022)
- Authors:
- Pandey, Ramendra Pati
- Nascimento, Marilda Savoia

- Franco, Caio Haddad

- Bortoluci, Karina

- Silva, Marcelo Nunes da

- Zingales, Bianca

- Gibald, Daniel
- Barrios, Leda Castaño
- Vieira, Joseli Lannes

- Cariste, Leonardo Moro
- Vasconcelos, Jose Ronnie

- Moraes, Carolina Borsoi

- Freitas Junior, Lucio H
- Kalil Filho, Jorge Elias

- Alcântara, Laura
- Cunha Neto, Edecio

- USP affiliated authors: NASCIMENTO, MARILDA SAVOIA - FM ; SILVA, MARCELO NUNES - IQ ; ZINGALES, BIANCA SILVANA - IQ ; KALIL FILHO, JORGE ELIAS - FM ; CUNHA NETO, EDECIO - FM
- Unidades: FM; IQ
- DOI: 10.1128/aac.00284-22
- Subjects: DOENÇA DE CHAGAS; MEDICAMENTO
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Washington
- Date published: 2022
- Source:
- Título: Antimicrobial Agents and Chemotherapy
- ISSN: 0066-4804
- Volume/Número/Paginação/Ano: v. 66, n. 11, p. 1-17, art. e0028422, 2022
- Status:
- Artigo possui versão em acesso aberto em repositório (Green Open Access)
- Versão do Documento:
- Versão submetida (Pré-print)
- Acessar versão aberta:
-
ABNT
PANDEY, Ramendra Pati et al. Drug repurposing in chagas disease: chloroquine potentiates benznidazole activity against Trypanosoma cruzi In vitro and in vivo. Antimicrobial Agents and Chemotherapy, v. 66, n. 11, p. 1-17, 2022Tradução . . Disponível em: https://doi.org/10.1128/aac.00284-22. Acesso em: 16 abr. 2026. -
APA
Pandey, R. P., Nascimento, M. S., Franco, C. H., Bortoluci, K., Silva, M. N. da, Zingales, B., et al. (2022). Drug repurposing in chagas disease: chloroquine potentiates benznidazole activity against Trypanosoma cruzi In vitro and in vivo. Antimicrobial Agents and Chemotherapy, 66( 11), 1-17. doi:10.1128/aac.00284-22 -
NLM
Pandey RP, Nascimento MS, Franco CH, Bortoluci K, Silva MN da, Zingales B, Gibald D, Barrios LC, Vieira JL, Cariste LM, Vasconcelos JR, Moraes CB, Freitas Junior LH, Kalil Filho JE, Alcântara L, Cunha Neto E. Drug repurposing in chagas disease: chloroquine potentiates benznidazole activity against Trypanosoma cruzi In vitro and in vivo [Internet]. Antimicrobial Agents and Chemotherapy. 2022 ; 66( 11): 1-17.[citado 2026 abr. 16 ] Available from: https://doi.org/10.1128/aac.00284-22 -
Vancouver
Pandey RP, Nascimento MS, Franco CH, Bortoluci K, Silva MN da, Zingales B, Gibald D, Barrios LC, Vieira JL, Cariste LM, Vasconcelos JR, Moraes CB, Freitas Junior LH, Kalil Filho JE, Alcântara L, Cunha Neto E. Drug repurposing in chagas disease: chloroquine potentiates benznidazole activity against Trypanosoma cruzi In vitro and in vivo [Internet]. Antimicrobial Agents and Chemotherapy. 2022 ; 66( 11): 1-17.[citado 2026 abr. 16 ] Available from: https://doi.org/10.1128/aac.00284-22 - Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease
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- Polymorphisms in genes affecting interferon-gamma production and Th1 T Cell differentiation are associated with progression to chagas disease cardiomyopathy (vol 11, 1386, 2020)
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