Artigo de periodico

Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-l-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes (2022)

• Authors:
  • Álvarez, Natalia
  • Leite, Celisnolia Morais
  • Napoleone, Adriana
  • Mendes, Luís Felipe Santos
  • Fernández, Carlos Y.
  • Ribeiro, Ronny R.
  • Ellena, Javier
  • Batista, Alzir Azevedo
  • Costa Filho, Antonio José da
  • Facchin, Gianella
• USP affiliated authors: ELLENA, JAVIER ALCIDES - IFSC ; COSTA FILHO, ANTÔNIO JOSÉ DA - FFCLRP ; MENDES, LUIS FELIPE SANTOS - FFCLRP
• Unidades: IFSC; FFCLRP
• DOI: 10.1007/s00775-022-01938-3
• Subjects: NEOPLASIAS (TRATAMENTO); CRISTALOGRAFIA; PLANEJAMENTO DE FÁRMACOS
• Keywords: Copper complexes; Dipeptide; 3,4,7,8-tetramethyl-1,10-phenanthroline; X-ray diffraction; DNA interaction; Cytotoxic activity
• Agências de fomento:
  • Financiamento CSIC/UDELAR
  • Financiamento PEDECIBA
  • Financiamento ANII
  • Financiamento FAPESP
  • Financiamento CNPq
• Language: Inglês
• Imprenta:
  • Publisher place: New York
  • Date published: 2022
• Source:
  • Título: Journal of Biological Inorganic Chemistry
  • ISSN: 0949-8257
  • Volume/Número/Paginação/Ano: v. 27, n. 4-5, p. 431-441, Aug. 2022

Informações sobre o DOI: 10.1007/s00775-022-01938-3 (Fonte: oaDOI API)
• Este periódico é de assinatura
• Este artigo NÃO é de acesso aberto
  
• Cor do Acesso Aberto: closed

---

Download do texto completo

Tipo	Nome	Link
	3092137.pdf

How to cite

A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas

• ABNT

  ÁLVAREZ, Natalia et al. Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-l-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes. Journal of Biological Inorganic Chemistry, v. 27, n. 4-5, p. 431-441, 2022Tradução . . Disponível em: https://doi.org/10.1007/s00775-022-01938-3. Acesso em: 27 dez. 2025.

• APA

  Álvarez, N., Leite, C. M., Napoleone, A., Mendes, L. F. S., Fernández, C. Y., Ribeiro, R. R., et al. (2022). Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-l-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes. Journal of Biological Inorganic Chemistry, 27( 4-5), 431-441. doi:10.1007/s00775-022-01938-3

• NLM

  Álvarez N, Leite CM, Napoleone A, Mendes LFS, Fernández CY, Ribeiro RR, Ellena J, Batista AA, Costa Filho AJ da, Facchin G. Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-l-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes [Internet]. Journal of Biological Inorganic Chemistry. 2022 ; 27( 4-5): 431-441.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1007/s00775-022-01938-3

• Vancouver

  Álvarez N, Leite CM, Napoleone A, Mendes LFS, Fernández CY, Ribeiro RR, Ellena J, Batista AA, Costa Filho AJ da, Facchin G. Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-l-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes [Internet]. Journal of Biological Inorganic Chemistry. 2022 ; 27( 4-5): 431-441.[citado 2025 dez. 27 ] Available from: https://doi.org/10.1007/s00775-022-01938-3

Últimas obras dos mesmos autores vinculados com a USP cadastradas na BDPI:

• Synthesis and structural characterization of a series of ternary copper(II)-L-dipeptide-neocuproine complexes: study of their cytotoxicity against cancer cells including MDA-MB-231, triple negative breast cancer cells
• A gold revision of the Golgi dynamics (GOLD) domain structure and associated cell functionalities
• Phenanthroline and phenyl carboxylate mixed ligand copper complexes in developing drugs to treat cancer
• Development of new copper coordination compounds as possible drugs to fight cancer
• Small molecule crystallography aiding the search for novel antimicrobial agents: design, characterization and QSAR studies of adamantane containing complexes
• A novel Cu(II) ternary complex with iminodiacetate and dimethyl-bipyridine: synthesis, characterization and DNA interaction
• Semiquantitative analysis of intermolecular interactions in the development of potential metallopharmaceuticals
• Development of copper(II)-diimine-iminodiacetate mixed ligand complexes as potential antitumor agents
• New Cu complexes containing methyl-phenanthroline and dipeptides as cytotoxic agents: synthesis, characterization and in vitro studies
• Structural characterization of [Cu(iminodiacetate)(diimine)] coordination complexes with in vitro antiproliferative activity