Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-HT1A and CB1 receptors (2021)
- Authors:
- USP affiliated authors: PADOVAN, CLAUDIA MARIA - FFCLRP ; COIMBRA, NORBERTO CYSNE - FMRP ; FREITAS, RENATO LEONARDO DE - FMRP ; MEDEIROS, PRISCILA DE - FMRP ; FERRARI, SYLMARA ESTHER NEGRINI - FMRP ; MEDEIROS, ANA CAROLINA - FMRP
- Unidades: FFCLRP; FMRP
- DOI: 10.1016/j.brainresbull.2021.06.017
- Subjects: CANABINOIDES; DOR CRÔNICA; COBALTO; DEPRESSÃO; FARMACOTERAPIA; CÓRTEX PRÉ-FRONTAL; CANABINOIDES; SEROTONINA; SINAPSE
- Keywords: Cobalt chloride; Cannabidiol; CB1 cannabinoid receptor; 5-HT1A serotonergic receptor; Depression-associated behaviours; Forced swim test; Prelimbic medial prefrontal cortex; Chronic neuropathic pain; Mechanical allodynia; Von Frey test
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Philadelphia
- Date published: 2021
- Source:
- Título: Brain Research Bulletin
- ISSN: 0361-9230
- Volume/Número/Paginação/Ano: v. 174, p. 323-338, 2021
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
MALVESTIO, Rafael Braghetto et al. Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-HT1A and CB1 receptors. Brain Research Bulletin, v. 174, p. 323-338, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.brainresbull.2021.06.017. Acesso em: 12 fev. 2026. -
APA
Malvestio, R. B., Medeiros, P. de, Negrini-Ferrari, S. E., Oliveira-Silva, M., Medeiros, A. C., Padovan, C. M., et al. (2021). Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-HT1A and CB1 receptors. Brain Research Bulletin, 174, 323-338. doi:10.1016/j.brainresbull.2021.06.017 -
NLM
Malvestio RB, Medeiros P de, Negrini-Ferrari SE, Oliveira-Silva M, Medeiros AC, Padovan CM, Luongo L, Maione S, Coimbra NC, Freitas RL de. Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-HT1A and CB1 receptors [Internet]. Brain Research Bulletin. 2021 ; 174 323-338.[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.brainresbull.2021.06.017 -
Vancouver
Malvestio RB, Medeiros P de, Negrini-Ferrari SE, Oliveira-Silva M, Medeiros AC, Padovan CM, Luongo L, Maione S, Coimbra NC, Freitas RL de. Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-HT1A and CB1 receptors [Internet]. Brain Research Bulletin. 2021 ; 174 323-338.[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.brainresbull.2021.06.017 - CB1-cannabinoid-, TRPV1-vanilloid- and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain symptoms
- The primary motor cortex electrical and chemical stimulation attenuates the chronic neuropathic pain by activation of the periaqueductal grey matter: the role of NMDA receptors
- N-methyl-d-aspartate receptors in the prelimbic cortex are critical for the maintenance of neuropathic pain
- Acanthoscurria gomesiana spider-derived synthetic mygalin in the dorsal raphe nucleus modulates acute and chronic pain
- Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice
- Inactivation and neurostimulation of the infralimbic medial prefrontal cortex on analgesia induced by electroacupuncture at 2hz and 2/100hz in animals with chronic neuropathic pain
- Infralimbic medial prefrontal cortex alters electroacupuncture effect in animals with neuropathic chronic pain
- Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury
- Cannabidiol in the dorsal hippocampus attenuates emotional and cognitive impairments related to neuropathic pain: the role of prelimbic neocortex-hippocampal connections
- Chemical neuroanatomical and psychopharmacological evidence that k receptor-mediated endogenous opioid peptide neurotransmission in the dorsal and ventral mesencephalon modulates panic-like behaviour
Informações sobre o DOI: 10.1016/j.brainresbull.2021.06.017 (Fonte: oaDOI API)
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