Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors (2021)
- Authors:
- USP affiliated authors: ZANON, NEUSA MARIA - FMRP ; NAVEGANTES, LUIZ CARLOS CARVALHO - FMRP ; KETTELHUT, ISIS DO CARMO - FMRP
- Unidade: FMRP
- DOI: 10.1016/j.lfs.2021.119563
- Subjects: ANTIDEPRESSIVOS; MÚSCULO ESQUELÉTICO; METABOLISMO DE PROTEÍNA; PROTEÍNAS DO TECIDO NERVOSO; TRANSDUÇÃO DE SINAL CELULAR
- Keywords: Diabetes mellitus; Proteolysis; Rolipram; Skeletal muscle; Ubiquitin-proteasome system
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Philadelphia
- Date published: 2021
- Source:
- Título: Life Sciences
- ISSN: 0024-3205
- Volume/Número/Paginação/Ano: v. 278, art. 119563, p. 1-12, 2021
- Este artigo possui versão em acesso aberto
- URL de acesso aberto
- Versão do Documento: Versão submetida (Pré-print)
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Status: Artigo possui versão em acesso aberto em repositório (Green Open Access) -
ABNT
ARCARO, Carlos Alberto et al. Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors. Life Sciences, v. 278, p. 1-12, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.lfs.2021.119563. Acesso em: 10 mar. 2026. -
APA
Arcaro, C. A., Assis, R. P., Oliveira, J. O., Zanon, N. M., Paula-Gomes, S., Navegantes, L. C. C., et al. (2021). Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors. Life Sciences, 278, 1-12. doi:10.1016/j.lfs.2021.119563 -
NLM
Arcaro CA, Assis RP, Oliveira JO, Zanon NM, Paula-Gomes S, Navegantes LCC, Kettelhut I do C, Brunetti IL, Baviera AM. Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors [Internet]. Life Sciences. 2021 ; 278 1-12.[citado 2026 mar. 10 ] Available from: https://doi.org/10.1016/j.lfs.2021.119563 -
Vancouver
Arcaro CA, Assis RP, Oliveira JO, Zanon NM, Paula-Gomes S, Navegantes LCC, Kettelhut I do C, Brunetti IL, Baviera AM. Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors [Internet]. Life Sciences. 2021 ; 278 1-12.[citado 2026 mar. 10 ] Available from: https://doi.org/10.1016/j.lfs.2021.119563 - Oxytocin induces anti-catabolic and anabolic effects on protein metabolism in the female rat oxidative skeletal muscle
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