Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and Burnout among frontline health care workers during the COVID-19 pandemic: a randomized clinical trial (2021)
- Authors:
- Crippa, José Alexandre de Souza
- Zuardi, Antonio Waldo
- Guimarães, Francisco Silveira
- Campos, Alline Cristina de
- Osório, Flávia de Lima
- Loureiro, Sonia Regina
- Santos, Rafael Guimarães dos
- Souza, José Diogo dos Santos
- Ushirohira, Juliana Mayumi
- Pacheco, Júlia Cozar
- Ferreira, Rafael Rinaldi
- Costa, Karla Cristinne Mancini
- Scomparin, Davi Silveira
- Scarante, Franciele Franco
- Santos, Isabela Pires dos
- Mechoulam, Raphael
- Kapczinski, Flávio
- Fonseca, Benedito Antonio Lopes da
- Esposito, Danillo Lucas Alves
- Lima, Karina Pereira
- Sen, Srijan
- Andraus, Maristela Haddad
- Hallak, Jaime Eduardo Cecilio
- Crippa, José Alexandre de Souza
- USP affiliated authors: CRIPPA, JOSÉ ALEXANDRE DE SOUZA - FMRP ; ZUARDI, ANTONIO WALDO - FMRP ; GUIMARÃES, FRANCISCO SILVEIRA - FMRP ; CAMPOS, ALLINE CRISTINA DE - FMRP ; OSORIO, FLAVIA DE LIMA - FMRP ; LOUREIRO, SONIA REGINA - FMRP ; FONSECA, BENEDITO ANTONIO LOPES DA - FMRP ; HALLAK, JAIME EDUARDO CECILIO - FMRP ; LIMA, KARINA PEREIRA - FMRP ; SANTOS, RAFAEL GUIMARÃES DOS - FMRP ; SOUZA, JOSÉ DIOGO DOS SANTOS - FMRP ; PACHECO, JÚLIA COZAR - FMRP ; COSTA, KARLA CRISTINNE MANCINI - FMRP ; SCOMPARIN, DAVI SILVEIRA - FMRP ; SCARANTE, FRANCIELE FRANCO - FMRP ; SANTOS, ISABELA PIRES DOS - FMRP ; ESPOSITO, DANILLO LUCAS ALVES - FMRP
- Unidade: FMRP
- DOI: 10.1001/jamanetworkopen.2021.20603
- Subjects: CANABINOIDES; ANSIOLÍTICOS; ESTRESSE PROFISSIONAL; EQUIPE DE ASSISTÊNCIA AO PACIENTE; COVID-19; FARMACOTERAPIA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: JAMA Network Open
- ISSN: 2574-3805
- Volume/Número/Paginação/Ano: v. 4, n. 8, art. e2120603, 2021
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
CRIPPA, José Alexandre de Souza et al. Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and Burnout among frontline health care workers during the COVID-19 pandemic: a randomized clinical trial. JAMA Network Open, v. 4, n. 8, 2021Tradução . . Disponível em: https://doi.org/10.1001/jamanetworkopen.2021.20603. Acesso em: 08 abr. 2026. -
APA
Crippa, J. A. de S., Zuardi, A. W., Guimarães, F. S., Campos, A. C. de, Osório, F. de L., Loureiro, S. R., et al. (2021). Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and Burnout among frontline health care workers during the COVID-19 pandemic: a randomized clinical trial. JAMA Network Open, 4( 8). doi:10.1001/jamanetworkopen.2021.20603 -
NLM
Crippa JA de S, Zuardi AW, Guimarães FS, Campos AC de, Osório F de L, Loureiro SR, Santos RG dos, Souza JD dos S, Ushirohira JM, Pacheco JC, Ferreira RR, Costa KCM, Scomparin DS, Scarante FF, Santos IP dos, Mechoulam R, Kapczinski F, Fonseca BAL da, Esposito DLA, Lima KP, Sen S, Andraus MH, Hallak JEC. Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and Burnout among frontline health care workers during the COVID-19 pandemic: a randomized clinical trial [Internet]. JAMA Network Open. 2021 ; 4( 8):[citado 2026 abr. 08 ] Available from: https://doi.org/10.1001/jamanetworkopen.2021.20603 -
Vancouver
Crippa JA de S, Zuardi AW, Guimarães FS, Campos AC de, Osório F de L, Loureiro SR, Santos RG dos, Souza JD dos S, Ushirohira JM, Pacheco JC, Ferreira RR, Costa KCM, Scomparin DS, Scarante FF, Santos IP dos, Mechoulam R, Kapczinski F, Fonseca BAL da, Esposito DLA, Lima KP, Sen S, Andraus MH, Hallak JEC. Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and Burnout among frontline health care workers during the COVID-19 pandemic: a randomized clinical trial [Internet]. JAMA Network Open. 2021 ; 4( 8):[citado 2026 abr. 08 ] Available from: https://doi.org/10.1001/jamanetworkopen.2021.20603 - Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic
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