Cyclosporine and chronic irritative factors as combined agents in the etiopathogenesis of gingival hyperplasia: case report (2021)
- Authors:
- Autor USP: DOMANESCHI, CARINA - FO
- Unidade: FO
- Subjects: HIPERPLASIA GENGIVAL; CICLOSPORINAS
- Language: Português
- Abstract: This paper reports the clinical case of a 25-year-old male patient that presented to the dentistry division complaining of significant gum bleeding episodes while brushing the teeth. He was previously diagnosed with aplastic anemia and was under immunosuppression therapy with cyclosporine. On clinical examination, poor oral hygiene, gingivitis, and extensive fibrotic areas compatible with gingival hyperplasia were noticed. Oral hygiene orientation was performed along with chlorhexidine digluconate 0,12% prescription. Scaling and root planning sessions were carried out every 2 weeks, under antibiotic therapy with amoxicillin 500mg, every 8h, beginning 48h before intervention. In two months, hyperplastic areas diminished, and no gingival bleeding was detected. Chronic irritative factors, as the presence of bacterial plaque, are related to the etiopathogenesis of gingival hyperplasia; furthermore, it is well-established that immunosuppressors are also responsible for abnormal overgrowth of gingival tissue. Studies describe that Cyclosporine increases interleukin 6 secretion, stimulating gingival fibroblasts to produce more collagen and glycosaminoglycans. Patients using such medications need regular dental follow-up, intending to promote adequate oral hygiene measures to inhibit such occurrences, as well as implement appropriate protocols in the presence of lesions. Accordingly, the dental surgeon must be integrated into the multidisciplinary healthcare team, contributing to the control of morbidities in medically complex patients
- Imprenta:
- Source:
- Título do periódico: Brazilian Oral Research
- ISSN: 1807-3107
- Volume/Número/Paginação/Ano: v. 35, supl. 3, p. 470, res. RCR230, 2021
- Conference titles: Proceedings of the SBPqO Annual Meeting
-
ABNT
MACEDO, L. F. S. L et al. Cyclosporine and chronic irritative factors as combined agents in the etiopathogenesis of gingival hyperplasia: case report. Brazilian Oral Research. São Paulo: SBPqO. . Acesso em: 24 abr. 2024. , 2021 -
APA
Macedo, L. F. S. L., Peres, M. P. S. M., Franco, J. B., & Domaneschi, C. (2021). Cyclosporine and chronic irritative factors as combined agents in the etiopathogenesis of gingival hyperplasia: case report. Brazilian Oral Research. São Paulo: SBPqO. -
NLM
Macedo LFSL, Peres MPSM, Franco JB, Domaneschi C. Cyclosporine and chronic irritative factors as combined agents in the etiopathogenesis of gingival hyperplasia: case report. Brazilian Oral Research. 2021 ; 35 470.[citado 2024 abr. 24 ] -
Vancouver
Macedo LFSL, Peres MPSM, Franco JB, Domaneschi C. Cyclosporine and chronic irritative factors as combined agents in the etiopathogenesis of gingival hyperplasia: case report. Brazilian Oral Research. 2021 ; 35 470.[citado 2024 abr. 24 ] - Qualidade de vida relacionada à saúde bucal de pacientes pediátricos com aids
- Hemostatic agents in tissue regeneration
- Evaluation of infections by Candida at a university hospital of Vale do Paraíba region, São Paulo State, Brazil: species distribution, colonization, risk factors and antifungal susceptibility
- Cárie relacionada à radiação
- Hospital treatment of subcutaneous hematoma due to chin liposuction: an unusual case report
- Disgeusia no paciente com câncer de cabeça e pescoço - como a odontologia e a nutrição podem trabalhar juntas
- Elaboração de material educativo para alunos de ensino fundamental, voltado à ciência e saúde
- Prevalência de colonização e infecção bucal por Candida e de cárie não-tratada em pacientes pediátricos com aids
- Fatores associados à qualidade de vida de crianças de 2 a 7 anos atendidas no Setor de Urgência da FOUSP
- Preliminary Study of the Prevalence of Oral Cancer in a Stomatology Course of Public Health System – Sp/Brazil
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
