Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism (2021)
- Authors:
- USP affiliated authors: ALVES FILHO, JOSÉ CARLOS FARIAS - FMRP ; CUNHA, THIAGO MATTAR - FMRP ; CUNHA, FERNANDO DE QUEIROZ - FMRP ; DAMASCENO, LUIS EDUARDO ALVES - FMRP ; SONEGO, ANDREZA BUZOLIN - FMRP ; ROSA, MARCOS HENRIQUE - FMRP ; MARTINS, TIMNA VARELA - FMRP
- Unidade: FMRP
- DOI: 10.1016/j.intimp.2020.107278
- Subjects: ANTI-INFLAMATÓRIOS; DIFERENCIAÇÃO CELULAR; CITOCINAS; GENÉTICA; MEDULA ESPINHAL; LINFÓCITOS T
- Keywords: EAE; Multiple sclerosis; Neuroinflammation; Pitavastatin; Th17; Treg
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: International Immunopharmacology
- ISSN: 1567-5769
- Volume/Número/Paginação/Ano: v. 91, art. 107278, 2021
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
PRADO, Douglas Silva et al. Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism. International Immunopharmacology, v. 91, 2021Tradução . . Disponível em: https://doi.org/10.1016/j.intimp.2020.107278. Acesso em: 12 fev. 2026. -
APA
Prado, D. S., Damasceno, L. E. A., Sonego, A. B., Rosa, M. H., Martins, T. V., Fonseca, M. D. M., et al. (2021). Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism. International Immunopharmacology, 91. doi:10.1016/j.intimp.2020.107278 -
NLM
Prado DS, Damasceno LEA, Sonego AB, Rosa MH, Martins TV, Fonseca MDM, Cunha TM, Cunha F de Q, Alves Filho JCF. Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism [Internet]. International Immunopharmacology. 2021 ; 91[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.intimp.2020.107278 -
Vancouver
Prado DS, Damasceno LEA, Sonego AB, Rosa MH, Martins TV, Fonseca MDM, Cunha TM, Cunha F de Q, Alves Filho JCF. Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism [Internet]. International Immunopharmacology. 2021 ; 91[citado 2026 fev. 12 ] Available from: https://doi.org/10.1016/j.intimp.2020.107278 - A clinically-relevant STING agonist restrains human TH17 cell inflammatory profile
- Cinnamoyloxy-mammeisin, a coumarin from propolis of stingless bees, attenuates Th17 cell differentiation and autoimmune inflammation via STAT3 inhibition
- Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-kB and oxidative stress
- Toll like receptor 9 deficiency in neutrophil improves sepsis outcome preventing down-regulation of CXCR2
- Splenectomy increases neutrophil migration but does not affect mortality in lethal sepsis
- Targeting IL-33/ST2 signaling: regulation of immune function and analgesia
- Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects
- Targeting nitric oxide as a key modulator of sepsis, arthritis and pain
- Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-kB activation
- The citrus flavanone naringenin reduces gout-induced joint pain and inflammation in mice by inhibiting the activation of NFκB and macrophage release of IL-1β
Informações sobre o DOI: 10.1016/j.intimp.2020.107278 (Fonte: oaDOI API)
Download do texto completo
| Tipo | Nome | Link | |
|---|---|---|---|
 |
003035684.pdf |
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
