Simvastatin prevents long-term cognitive deficits in sepsis survivor rats by reducing neuroinflammation and neurodegeneration (2020)
- Authors:
- USP affiliated authors: CATALÃO, CARLOS HENRIQUE ROCHA - FMRP ; CARNIO, EVELIN CAPELLARI - EERP ; SEBOLLELA, ADRIANO SILVA - FMRP ; ALBERICI, LUCIANE CARLA - FCFRP ; ROCHA, MARIA JOSE ALVES DA - FORP ; COSTA, LUÍS HENRIQUE ANGENENDT DA - FMRP
- Unidades: FMRP; EERP; FCFRP; FORP
- DOI: 10.1007/s12640-020-00222-z
- Subjects: ENCEFALOPATIA ANIMAL; HIPOCAMPO; CÓRTEX PRÉ-FRONTAL; ASTRÓCITOS
- Keywords: Astrocytes; Encephalopathy; Hippocampus; Neurodegeneration; Microglia; Prefrontal cortex
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Neurotoxicity Research
- ISSN: 1029-8428
- Volume/Número/Paginação/Ano: v. 38, n. 4, p. 871-886, 2020
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
CATALÃO, Carlos Henrique Rocha et al. Simvastatin prevents long-term cognitive deficits in sepsis survivor rats by reducing neuroinflammation and neurodegeneration. Neurotoxicity Research, v. 38, n. 4, p. 871-886, 2020Tradução . . Disponível em: https://doi.org/10.1007/s12640-020-00222-z. Acesso em: 26 jan. 2026. -
APA
Catalão, C. H. R., Santos Junior, N. N. dos, Costa, L. H. A. da, Souza, A. O., Cárnio, E. C., Sebollela, A. S., et al. (2020). Simvastatin prevents long-term cognitive deficits in sepsis survivor rats by reducing neuroinflammation and neurodegeneration. Neurotoxicity Research, 38( 4), 871-886. doi:10.1007/s12640-020-00222-z -
NLM
Catalão CHR, Santos Junior NN dos, Costa LHA da, Souza AO, Cárnio EC, Sebollela AS, Alberici LC, Rocha MJA da. Simvastatin prevents long-term cognitive deficits in sepsis survivor rats by reducing neuroinflammation and neurodegeneration [Internet]. Neurotoxicity Research. 2020 ; 38( 4): 871-886.[citado 2026 jan. 26 ] Available from: https://doi.org/10.1007/s12640-020-00222-z -
Vancouver
Catalão CHR, Santos Junior NN dos, Costa LHA da, Souza AO, Cárnio EC, Sebollela AS, Alberici LC, Rocha MJA da. Simvastatin prevents long-term cognitive deficits in sepsis survivor rats by reducing neuroinflammation and neurodegeneration [Internet]. Neurotoxicity Research. 2020 ; 38( 4): 871-886.[citado 2026 jan. 26 ] Available from: https://doi.org/10.1007/s12640-020-00222-z - Microglial activation modulates neuroendocrine secretion during experimental sepsis
- Corticosterone and adrenocorticotrophic hormone secretion is recovered after immune challenge or acute restraint stress in sepsis survivor animals
- Pre-treatment and continuous administration of simvastatin during sepsis improve metabolic parameters and prevent CNS injuries in survivor rats
- Kaolin-induced hydrocephalus causes acetylcholinesterase activity dysfunction following hypothalamic damage in infant rats
- Brain oxidative stress during experimental sepsis is attenuated by simvastatin administration
- Oxytocin affects nitric oxide and cytokine production by sepsis-sensitized macrophages
- Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis
- Experimental sepsis induces sustained inflammation and acetylcholinesterase activity impairment in the hypothalamus
- Sepsis-induced encephalopathy impairs descending nociceptive pathways in rats
- Neuroprotective action of Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) acids on Paraquat intoxication in Drosophila melanogaster
Informações sobre o DOI: 10.1007/s12640-020-00222-z (Fonte: oaDOI API)
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