Antibody fragments as tools for elucidating structure-toxicity relationships and for diagnostic/therapeutic targeting of neurotoxic amyloid oligomers (2020)
- Authors:
- USP affiliated authors: SEBOLLELA, ADRIANO SILVA - FMRP ; CAMPOS, RAQUEL MARIA DE - FMRP
- Unidade: FMRP
- DOI: 10.3390/ijms21238920
- Subjects: ANTICORPOS; AMILOIDOSE; IMUNOGLOBULINAS; IMUNOLOGIA; PATOLOGIA
- Keywords: NUsc1; Amyloid; Antibody fragments; Neurotoxicity; Oligomer; Single chain
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: International Journal of Molecular Sciences
- ISSN: 1422-0067
- Volume/Número/Paginação/Ano: v. 21, n. 23, art. 8920, 2020
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
BITENCOURT, André Luiz Brandão et al. Antibody fragments as tools for elucidating structure-toxicity relationships and for diagnostic/therapeutic targeting of neurotoxic amyloid oligomers. International Journal of Molecular Sciences, v. 21, n. 23, 2020Tradução . . Disponível em: https://doi.org/10.3390/ijms21238920. Acesso em: 28 dez. 2025. -
APA
Bitencourt, A. L. B., Campos, R. M. de, Cline, E. N., Klein, W. L., & Sebollela, A. S. (2020). Antibody fragments as tools for elucidating structure-toxicity relationships and for diagnostic/therapeutic targeting of neurotoxic amyloid oligomers. International Journal of Molecular Sciences, 21( 23). doi:10.3390/ijms21238920 -
NLM
Bitencourt ALB, Campos RM de, Cline EN, Klein WL, Sebollela AS. Antibody fragments as tools for elucidating structure-toxicity relationships and for diagnostic/therapeutic targeting of neurotoxic amyloid oligomers [Internet]. International Journal of Molecular Sciences. 2020 ; 21( 23):[citado 2025 dez. 28 ] Available from: https://doi.org/10.3390/ijms21238920 -
Vancouver
Bitencourt ALB, Campos RM de, Cline EN, Klein WL, Sebollela AS. Antibody fragments as tools for elucidating structure-toxicity relationships and for diagnostic/therapeutic targeting of neurotoxic amyloid oligomers [Internet]. International Journal of Molecular Sciences. 2020 ; 21( 23):[citado 2025 dez. 28 ] Available from: https://doi.org/10.3390/ijms21238920 - A conformation sensitive fragment antibody-based assay allows isolation of a neurotoxic oligomeric assembly of the β-amyloid peptide under non-denaturing condition
- Caracterização preliminar do isolamento de oligômeros do peptídeo β-amiloide utilizando o anticorpo de cadeia única NUsc1
- Elucidating molecular mass and shape of a neurotoxic Aβ oligomer
- Memory recovery through gene therapy with a single chain antibody fragment selective for Aβ oligomers in a model of Alzheimer’s disease in rats
- Novas abordagens para detecção e caracterização bioquímica dos principais biomarcadores da doença de Alzheimer
- Fragmentos de anticorpos do tipo scFv anti-oligômeros do peptídeo-amiloide como ferramenta de estudo e estratégia diagnóstica e terapêutica para a D. Alzheimer
- Quantitative evaluation of the binding of the scFv antibody NUsc1 to Alzheimer’s Disease-Associated Aβ oligomers using Surface plasmon Resonance
- A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers
- A freeze-and-thaw-induced fragment of the microtubule-associated protein tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity
- AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models
Informações sobre o DOI: 10.3390/ijms21238920 (Fonte: oaDOI API)
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