Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1 (2021)
- Authors:
- USP affiliated authors: CASTRO, VIRGÍNIA PICANÇO E - FMRP ; COVAS, DIMAS TADEU - FMRP ; RUSSO, ELISA MARIA DE SOUSA - FCFRP
- Unidades: FMRP; FCFRP
- DOI: 10.1007/s10529-020-03040-7
- Subjects: FATORES DE COAGULAÇÃO SANGUÍNEA; HEMOFILIA; LINHAGEM CELULAR
- Keywords: Blood coagulation factors; Hemophilia B; Human cell line SK-Hep-1; Recombinant human factor IX
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Biotechnology Letters
- ISSN: 0141-5492
- Volume/Número/Paginação/Ano: v. 43, n. 1, p. 143-152, 2021
- Status:
- Nenhuma versão em acesso aberto identificada
-
ABNT
BOMFIM, Aline de Sousa et al. Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1. Biotechnology Letters, v. 43, n. 1, p. 143-152, 2021Tradução . . Disponível em: https://doi.org/10.1007/s10529-020-03040-7. Acesso em: 29 mar. 2026. -
APA
Bomfim, A. de S., Freitas, M. C. C. de, Castro, V. P. e, Soares Neto, M. A., Pádua, R., Covas, D. T., & Russo, E. M. de S. (2021). Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1. Biotechnology Letters, 43( 1), 143-152. doi:10.1007/s10529-020-03040-7 -
NLM
Bomfim A de S, Freitas MCC de, Castro VP e, Soares Neto MA, Pádua R, Covas DT, Russo EM de S. Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1 [Internet]. Biotechnology Letters. 2021 ; 43( 1): 143-152.[citado 2026 mar. 29 ] Available from: https://doi.org/10.1007/s10529-020-03040-7 -
Vancouver
Bomfim A de S, Freitas MCC de, Castro VP e, Soares Neto MA, Pádua R, Covas DT, Russo EM de S. Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1 [Internet]. Biotechnology Letters. 2021 ; 43( 1): 143-152.[citado 2026 mar. 29 ] Available from: https://doi.org/10.1007/s10529-020-03040-7 - Integration pattern of HIV-1 based lentiviral vector carrying recombinant coagulation factor VIII in Sk-Hep and 293T cells
- An enhancer/promoter combination strengthens the expression of blood-coagulation factor VIII in non-viral expression vectors
- Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII
- Lentiviral-mediated gene transfer: a patent review
- Forced expression of OCT4 influences the expression of pluripotent genes in human mesenchymal stem cells and fibroblasts
- Approaches for recombinant human factor IX production in serum-free suspension cultures
- Pluripotent reprogramming of fibroblasts by lentiviralmediated insertion of SOX2, C-MYC, and TCL-1A
- Ten years of iPSC: clinical potential and advances in vitro hematopoietic differentiation
- Produção de fator IX recombinante nas células humanas 293T E SK-HEP-1 e avaliação da expressão de genes relacionados à gama-carboxilação
- Murine leukemia virus-derived retroviral vector has differential integration patterns in human cell lines used to produce recombinant factor VIII
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