Serum folate and vitamin B12 status in young Brazilian children (2019)
- Authors:
- Autor USP: CARDOSO, MARLY AUGUSTO - FSP
- Unidade: FSP
- DOI: 10.1017/S1368980019000193
- Subjects: SAÚDE DA CRIANÇA; ESTADO NUTRICIONAL; ANEMIA; VITAMINA B12
- Language: Inglês
- Abstract: Objective:To assess the nutritional status of folate and vitamin B12with anaemia inyoung children.Design:A cross-sectional study was conducted at the primary health-care centresof four Brazilian cities. Folate and vitamin B12were assessed byfluoroimmuno-assay. Multilevel Poisson regression models were used to explore theassociation of folate and vitamin B12status in relation to anaemia in youngchildren.Setting:Brazil.Participants:Children (n460) aged 11 to 15 months.Results:The median (interquartile range) of serum folate was 39·7 (28·8–55·3)nmol/l and only four children presented with folate deficiency (<10 nmol/l).Surprisingly, 30·9 % of children presented with serum folate concentrations abovethe upper limit of detectable values by the commercial kit used for analysis. Thefrequency of vitamin B12deficiency (<148 pmol/l) was 15 % and it was inverselyassociated with the highest tertile of serum folate concentrations (P<0·001).Having high serum folate concentration (≥50·1 nmol/l) and vitamin B12≥148pmol/l was associated with lower frequency of anaemia in these children(prevalence ratio=0·53; 95% CI 0·30, 0·92).Conclusions:High frequency of elevated serum concentration of folate was foundamong young Brazilian children and 15 % of them had vitamin B12deficiency. Thecombination of high serum folate and normal vitamin B12status was associatedwith a lower frequency of anaemia in these children. Improvements in the currentstrategies to promote healthy food-based complementary feeding along withprevention and control of micronutrient deficiencies are recommended to improvechildren’s health
- Imprenta:
- Source:
- Título: Public Health Nutrition
- ISSN: 1368-9800
- Volume/Número/Paginação/Ano: v.22, n.7, p. 1223-1231, 2019
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: bronze
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ABNT
SILVA, Lara Lívia Santos da e FAWZI, Wafaie W e CARDOSO, Marly Augusto. Serum folate and vitamin B12 status in young Brazilian children. Public Health Nutrition, v. 22, n. 7, p. 1223-1231, 2019Tradução . . Disponível em: https://doi.org/10.1017/S1368980019000193. Acesso em: 04 ago. 2025. -
APA
Silva, L. L. S. da, Fawzi, W. W., & Cardoso, M. A. (2019). Serum folate and vitamin B12 status in young Brazilian children. Public Health Nutrition, 22( 7), 1223-1231. doi:10.1017/S1368980019000193 -
NLM
Silva LLS da, Fawzi WW, Cardoso MA. Serum folate and vitamin B12 status in young Brazilian children [Internet]. Public Health Nutrition. 2019 ;22( 7): 1223-1231.[citado 2025 ago. 04 ] Available from: https://doi.org/10.1017/S1368980019000193 -
Vancouver
Silva LLS da, Fawzi WW, Cardoso MA. Serum folate and vitamin B12 status in young Brazilian children [Internet]. Public Health Nutrition. 2019 ;22( 7): 1223-1231.[citado 2025 ago. 04 ] Available from: https://doi.org/10.1017/S1368980019000193 - Nutrition for the middle-aged and elderly: improving quality of life over adulthood
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Informações sobre o DOI: 10.1017/S1368980019000193 (Fonte: oaDOI API)
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