Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira (2019)
- Authors:
- USP affiliated authors: VASCONCELLOS, SILVIO ARRUDA - FMVZ ; HEINEMANN, MARCOS BRYAN - FMVZ
- Unidade: FMVZ
- DOI: 10.1038/s41598-018-37949-x
- Subjects: LEPTOSPIROSE; GENÉTICA BACTERIANA; ENGENHARIA GENÉTICA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título: Scientific Reports
- ISSN: 2045-2322
- Volume/Número/Paginação/Ano: v. 9, art. 1839, p. 1-14, 2019
- Status:
- Artigo publicado em periódico de acesso aberto (Gold Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
FERNANDES, L. G. V et al. Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira. Scientific Reports, v. 9, p. 1-14, 2019Tradução . . Disponível em: https://doi.org/10.1038/s41598-018-37949-x. Acesso em: 01 abr. 2026. -
APA
Fernandes, L. G. V., Guaman, L. P., Vasconcellos, S. A., Heinemann, M. B., Picardeau, M., & Nascimento, A. L. T. O. do. (2019). Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira. Scientific Reports, 9, 1-14. doi:10.1038/s41598-018-37949-x -
NLM
Fernandes LGV, Guaman LP, Vasconcellos SA, Heinemann MB, Picardeau M, Nascimento ALTO do. Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [Internet]. Scientific Reports. 2019 ; 9 1-14.[citado 2026 abr. 01 ] Available from: https://doi.org/10.1038/s41598-018-37949-x -
Vancouver
Fernandes LGV, Guaman LP, Vasconcellos SA, Heinemann MB, Picardeau M, Nascimento ALTO do. Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [Internet]. Scientific Reports. 2019 ; 9 1-14.[citado 2026 abr. 01 ] Available from: https://doi.org/10.1038/s41598-018-37949-x - Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans
- Evaluation of two novel leptospiral proteins for their interaction to human host components
- Evaluation of Lsa46 and Lsa77 Leptospiral proteins for their immunoprotective activities in hamster model of leptospirosis
- Characterization of two new putative adhesins of Leptospira interrogans
- A novel surface-exposed protein of Leptospira interrogans that interacts with the components of human terminal complement pathway
- The role of Lsa23 to mediate the interaction of Leptospira interrogans with the terminal complement components pathway
- Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans
- Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties
- Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components
- Multifunctional and redundant roles of Leptospira interrogans proteins in bacterial-adhesion and fibrin clotting inhibition
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