Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH (2016)
- Authors:
- Lotan, Tamara L
- Wei, Wei
- Ludkovski, Olga
- Morais, Carlos L
- Guedes, Liana B
- Jamaspishvili, Tamara
- Lopez, Karen
- Hawley, Sarah T
- Feng, Ziding
- Fazli, Ladan
- Hurtado-Coll, Antonio
- McKenney, Jesse K
- Simko, Jeffrey
- Carroll, Peter R
- Gleave, Martin
- Lin, Daniel W
- Nelson, Peter S
- Thompson, Ian M
- True, Lawrence D
- Brooks, James D
- Lance, Raymond
- Troyer, Dean
- Squire, Jeremy Andrew
- Autor USP: SQUIRE, JEREMY ANDREW - FMRP
- Unidade: FMRP
- DOI: 10.1038/modpathol.2016.88
- Subjects: NEOPLASIAS PROSTÁTICAS; BIOMARCADORES; IMUNOHISTOQUÍMICA
- Language: Inglês
- Imprenta:
- Source:
- Título: Modern Pathology
- ISSN: 0893-3952
- Volume/Número/Paginação/Ano: v. 29, n. 8, p. 904-914, 2016
- Status:
- Artigo possui acesso gratuito no site do editor (Bronze Open Access)
- Versão do Documento:
- Versão publicada (Published version)
- Acessar versão aberta:
-
ABNT
LOTAN, Tamara L et al. Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH. Modern Pathology, v. 29, n. 8, p. 904-914, 2016Tradução . . Disponível em: https://doi.org/10.1038/modpathol.2016.88. Acesso em: 31 mar. 2026. -
APA
Lotan, T. L., Wei, W., Ludkovski, O., Morais, C. L., Guedes, L. B., Jamaspishvili, T., et al. (2016). Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH. Modern Pathology, 29( 8), 904-914. doi:10.1038/modpathol.2016.88 -
NLM
Lotan TL, Wei W, Ludkovski O, Morais CL, Guedes LB, Jamaspishvili T, Lopez K, Hawley ST, Feng Z, Fazli L, Hurtado-Coll A, McKenney JK, Simko J, Carroll PR, Gleave M, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Lance R, Troyer D, Squire JA. Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH [Internet]. Modern Pathology. 2016 ; 29( 8): 904-914.[citado 2026 mar. 31 ] Available from: https://doi.org/10.1038/modpathol.2016.88 -
Vancouver
Lotan TL, Wei W, Ludkovski O, Morais CL, Guedes LB, Jamaspishvili T, Lopez K, Hawley ST, Feng Z, Fazli L, Hurtado-Coll A, McKenney JK, Simko J, Carroll PR, Gleave M, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Lance R, Troyer D, Squire JA. Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH [Internet]. Modern Pathology. 2016 ; 29( 8): 904-914.[citado 2026 mar. 31 ] Available from: https://doi.org/10.1038/modpathol.2016.88 - A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer
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- In silico shows that PTEN loss and AR overexpression are associated with increased CD8+ T-cell and Treg density and earlier disease recurrence in prostate cancer
- In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in sity hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading
- STAT1-associated intratumoural TH1 immunity predicts chemotherapy resistance in high-grade serous ovarian cancer
- PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy
- Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma
- Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data
- Application of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) for detecting PTEN loss in diagnostic prostate cancer needle biopsies
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