Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain (2016)
- Authors:
- USP affiliated authors: LAURETTI, GABRIELA ROCHA - FMRP ; COELHO, EDUARDO BARBOSA - FMRP ; LANCHOTE, VERA LUCIA - FCFRP
- Unidades: FMRP; FCFRP
- DOI: 10.1111/fcp.12168
- Subjects: ANALGÉSICOS; CITOCROMO P-450; ESTEROIDES
- Keywords: Clearance; CYP2B6; CYP3A; Fraction unbound; Tramadol
- Language: Inglês
- Imprenta:
- Publisher place: West Sussex
- Date published: 2016
- Source:
- Título: Fundamental and Clinical Pharmacology
- ISSN: 0767-3981
- Volume/Número/Paginação/Ano: v. 30, n. 2, p. 153-161, 2016
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
MORAES, Natália V. de et al. Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain. Fundamental and Clinical Pharmacology, v. 30, n. 2, p. 153-161, 2016Tradução . . Disponível em: https://doi.org/10.1111/fcp.12168. Acesso em: 13 fev. 2026. -
APA
Moraes, N. V. de, Lauretti, G. R., Coelho, E. B., Godoy, A. L. P. C., Neves, D. V., & Lanchote, V. L. (2016). Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain. Fundamental and Clinical Pharmacology, 30( 2), 153-161. doi:10.1111/fcp.12168 -
NLM
Moraes NV de, Lauretti GR, Coelho EB, Godoy ALPC, Neves DV, Lanchote VL. Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain [Internet]. Fundamental and Clinical Pharmacology. 2016 ; 30( 2): 153-161.[citado 2026 fev. 13 ] Available from: https://doi.org/10.1111/fcp.12168 -
Vancouver
Moraes NV de, Lauretti GR, Coelho EB, Godoy ALPC, Neves DV, Lanchote VL. Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain [Internet]. Fundamental and Clinical Pharmacology. 2016 ; 30( 2): 153-161.[citado 2026 fev. 13 ] Available from: https://doi.org/10.1111/fcp.12168 - The SLCO1A2 -189_-188InsA polymorphism reduces clearance of rocuronium in patients submitted to elective surgeries
- Analysis of rocuronium in human plasma by liquid chromatography–tandem mass spectrometry with application in clinical pharmacokinetics
- In vivo activity of CYP2D6 and enantioselective tramadol clearance in patients with neuropathic pain
- Effects of type 1 and type 2 diabetes on the pharmacokinetics of tramadol enantiomers in patients with neuropathic pain phenotyped as cytochrome P450 2D6 extensive metabolizers
- Enantioselective analysis of unbound tramadol, O-desmethyltramadol and N-desmethyltramadol in plasma by ultrafiltration and LC-MS/MS: application to clinical pharmacokinetics
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Informações sobre o DOI: 10.1111/fcp.12168 (Fonte: oaDOI API)
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