Molecular modeling and structure-activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain (2017)
- Authors:
- USP affiliated authors: ANDRICOPULO, RENATA KROGH - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; FERREIRA, ELIZABETH IGNE - FCF ; LOUREIRO, ANA PAULA DE MELO - FCF
- Unidades: IFSC; FCF
- DOI: 10.1007/s00044-016-1776-7
- Subjects: QUÍMICA MÉDICA; PRODUTOS NATURAIS; PLANTAS MEDICINAIS
- Keywords: Antiparasite drugs; Docking studies; Molecular hybridization; Bioisosterism
- Language: Inglês
- Imprenta:
- Source:
- Título: Medicinal Chemistry Research
- ISSN: 1054-2523
- Volume/Número/Paginação/Ano: v. 26, n. 4, p. 760-769, Apr. 2017
- Este artigo possui versão em acesso aberto
- URL de acesso aberto
- Versão do Documento: Versão submetida (Pré-print)
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Status: Artigo possui versão em acesso aberto em repositório (Green Open Access) -
ABNT
SERAFIM, Ricardo A. M. et al. Molecular modeling and structure-activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain. Medicinal Chemistry Research, v. 26, n. 4, p. 760-769, 2017Tradução . . Disponível em: https://doi.org/10.1007/s00044-016-1776-7. Acesso em: 13 mar. 2026. -
APA
Serafim, R. A. M., Oliveira, T. F., Loureiro, A. P. de M., Krogh, R., Andricopulo, A. D., Dias, L. C., & Ferreira, E. I. (2017). Molecular modeling and structure-activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain. Medicinal Chemistry Research, 26( 4), 760-769. doi:10.1007/s00044-016-1776-7 -
NLM
Serafim RAM, Oliveira TF, Loureiro AP de M, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Molecular modeling and structure-activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain [Internet]. Medicinal Chemistry Research. 2017 ; 26( 4): 760-769.[citado 2026 mar. 13 ] Available from: https://doi.org/10.1007/s00044-016-1776-7 -
Vancouver
Serafim RAM, Oliveira TF, Loureiro AP de M, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Molecular modeling and structure-activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain [Internet]. Medicinal Chemistry Research. 2017 ; 26( 4): 760-769.[citado 2026 mar. 13 ] Available from: https://doi.org/10.1007/s00044-016-1776-7 - Bioisoster hybrids of N-acylhydrazone and furoxan groups: is cruzain the target for those potential anti-T. cruzi compounds?
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- Application of bioisosterism approach in the design, synthesis, and biological evaluation of nitrofurazone derivatives as antichagasic candidates
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- Multi parametric optimization of a series of potent cruzain inhibitors as drug candidates for chagas disease
- Síntese total das marinoquinolinas A, B, C e E e análogos não-naturais
- SAR studies on a series of reversible competitive inhibitors of cruzain from Trypanosoma cruzi
- Synthesis of the macrolactone of migrastatin and analogues with potent cell-migration inhibitory activity
- Synthesis, electrochemical studies and anticancer activity of ferrocenyl oxindoles
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