Axially-modified paddlewheel diruthenium(II,III)-ibuprofenato metallodrugs and the influence of the structural modification on U87MG and A172 human glioma cell proliferation, apoptosis, mitosis and migration (2016)
- Authors:
- USP affiliated authors: COLQUHOUN, ALISON - ICB ; SILVA, DENISE DE OLIVEIRA - IQ
- Unidades: ICB; IQ
- DOI: 10.1016/j.jinorgbio.2016.10.003
- Subjects: GLIOMA; ANTI-INFLAMATÓRIOS NÃO ESTEROIDES
- Language: Inglês
- Imprenta:
- Source:
- Título: Journal of Inorganic Biochemistry
- ISSN: 0162-0134
- Volume/Número/Paginação/Ano: v. 165, p. 181-191, 2016
- Status:
- Artigo possui versão em acesso aberto em repositório (Green Open Access)
- Versão do Documento:
- Versão submetida (Pré-print)
- Acessar versão aberta:
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ABNT
REHMAN, Hanif Ur et al. Axially-modified paddlewheel diruthenium(II,III)-ibuprofenato metallodrugs and the influence of the structural modification on U87MG and A172 human glioma cell proliferation, apoptosis, mitosis and migration. Journal of Inorganic Biochemistry, v. 165, p. 181-191, 2016Tradução . . Disponível em: https://doi.org/10.1016/j.jinorgbio.2016.10.003. Acesso em: 31 mar. 2026. -
APA
Rehman, H. U., Freitas, T. E. de, Gomes, R. N., Colquhoun, A., & Silva, D. de O. (2016). Axially-modified paddlewheel diruthenium(II,III)-ibuprofenato metallodrugs and the influence of the structural modification on U87MG and A172 human glioma cell proliferation, apoptosis, mitosis and migration. Journal of Inorganic Biochemistry, 165, 181-191. doi:10.1016/j.jinorgbio.2016.10.003 -
NLM
Rehman HU, Freitas TE de, Gomes RN, Colquhoun A, Silva D de O. Axially-modified paddlewheel diruthenium(II,III)-ibuprofenato metallodrugs and the influence of the structural modification on U87MG and A172 human glioma cell proliferation, apoptosis, mitosis and migration [Internet]. Journal of Inorganic Biochemistry. 2016 ; 165 181-191.[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.jinorgbio.2016.10.003 -
Vancouver
Rehman HU, Freitas TE de, Gomes RN, Colquhoun A, Silva D de O. Axially-modified paddlewheel diruthenium(II,III)-ibuprofenato metallodrugs and the influence of the structural modification on U87MG and A172 human glioma cell proliferation, apoptosis, mitosis and migration [Internet]. Journal of Inorganic Biochemistry. 2016 ; 165 181-191.[citado 2026 mar. 31 ] Available from: https://doi.org/10.1016/j.jinorgbio.2016.10.003 - Inhibition of C6 rat glioma proliferation by ['RU IND. 2''CL''(ibp) IND. 4'] depends on changes in p21, p27, Bax/Bcl2 ratio and mitochondrial membrane potential
- The novel ruthenium—γ-linolenic complex [Ru2(aGLA)4Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro
- Growth inhibitory effects of the diruthenium-ibuprofen compound, 'RU IND. 2''CL'(Ibp)' IND. 4', in human glioma cells in vitro and in the rat C6 orthotopic glioma in vivo
- Diruthenium(II, III) complexes of ibuprofen, aspirin, naproxen and indomethacin non-steroidal anti-inflammatory drugs: synthesis, characterization and their effects on tumor-cell proliferation
- Time-dependent effects of a novel ruthenium complex containing the non-steroidal anti-inflammatory drug (NSAID) ibuprofen on the mRNA expression of proteins involved in cell cycle control, angiogenesis and invasion in C6 rat glioma cells In vitro
- Synthesis and characterization of new diruthenium (II, III) complexes with non-steroidal anti-inflammatory drugs
- Diruthenium(II,III)-non-steroidal anti-inflammatory drug complexes and their effects on tumor-cell proliferation
- Diruthenium (II,III)-ketoprofen anticancer metallodrug investigated for interaction with transferrin and for effects on the antiproliferative activity, apoptotic and mitotic processes in the A172 human glioma cell line
- Time-dependent effects of a novel ruthenium complex containing the non-steroidal anti-inflammatory drug (nsaid) ibuprofen on the mRNA expression of proteins involved in cell cycle control, Angiogenesis and Invasion in C6 rat glioma cells in vitro
- Anti-tumour properties of novel ruthenium complexes containing non-steroidal anti-inflamatory drugs (NSAIDs)
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