PPAR-'gama' activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production (2015)
- Authors:
- USP affiliated authors: SILVA, FRANCISCO WANDERLEY GARCIA DE PAULA E - FORP ; SORGI, CARLOS ARTERIO - FCFRP ; BORDON, KARLA DE CASTRO FIGUEIREDO - FCFRP ; BRAGA, ELIANE CANDIANI ARANTES - FCFRP ; FACCIOLI, LUCIA HELENA - FCFRP
- Unidades: FORP; FCFRP
- DOI: 10.1016/j.toxicon.2014.11.226
- Subjects: VENENOS DE ORIGEM ANIMAL; ESCORPIÕES; TOXINAS; LIPÍDEOS
- Language: Inglês
- Imprenta:
- Publisher place: Kidlington
- Date published: 2015
- Source:
- Status:
- Artigo possui versão em acesso aberto em repositório (Green Open Access)
- Versão do Documento:
- Versão submetida (Pré-print)
- Acessar versão aberta:
-
ABNT
ZOCCAL, Karina Furlani et al. PPAR-'gama' activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production. Toxicon, v. 93, p. 90-97, 2015Tradução . . Disponível em: https://doi.org/10.1016/j.toxicon.2014.11.226. Acesso em: 02 abr. 2026. -
APA
Zoccal, K. F., Silva, F. W. G. de P. e, Bitencourt, C. da S., Sorgi, C. A., Bordon, K. de C. F., Arantes, E. C., & Faccioli, L. H. (2015). PPAR-'gama' activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production. Toxicon, 93, 90-97. doi:10.1016/j.toxicon.2014.11.226 -
NLM
Zoccal KF, Silva FWG de P e, Bitencourt C da S, Sorgi CA, Bordon K de CF, Arantes EC, Faccioli LH. PPAR-'gama' activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production [Internet]. Toxicon. 2015 ; 93 90-97.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1016/j.toxicon.2014.11.226 -
Vancouver
Zoccal KF, Silva FWG de P e, Bitencourt C da S, Sorgi CA, Bordon K de CF, Arantes EC, Faccioli LH. PPAR-'gama' activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production [Internet]. Toxicon. 2015 ; 93 90-97.[citado 2026 abr. 02 ] Available from: https://doi.org/10.1016/j.toxicon.2014.11.226 - CD14,TLR2 and TLR4 are essential to macrophages recognize Tityus serrulatus venom and its toxin 1 and to release lipid mediators, IL-6 and TNFA
- TLR2, TLR4 and CD14 recognize venom-associated molecular patterns from Tityus serrulatus to induce macrophage-derived inflammatory mediators
- Partial purification and functional characterization of Ts19 Frag-I, a novel toxin from Tityus serrulatus scorpion venom
- Toxin Ts5 from Tityus serrulatus venom induces macrophage activation and cytokine production
- Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: evidence of a pro-inflammatory toxin on macrophages
- Toxins of Tityus serrulatus scorpion venom induce inflammatory mediators in vitro
- Macrophage activation and production of immune mediators induced by Tityus serrulatus venom, Ts1 and Ts2
- Tityus serrulatus venom induces lipid body formation through TLR2 and TLR4
- Ts6 and Ts2 from Tityus serrulatus venom induce inflammation by mechanisms dependent on lipid mediators and cytokine production
- Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators
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