Dipyrone metabolite 4-MAA induces hypothermia and inhibits PG'E IND.2'-dependent and -independent fever while 4-AA only blocks PG'E IND.2'-dependent fever (2014)
- Authors:
- USP affiliated authors: MELO, MIRIAM CRISTINA CONTIN DE - FCFRP ; JABOR, VALQUÍRIA APARECIDA POLISEL - FCFRP ; SOUZA, GLORIA EMILIA PETTO DE - FCFRP ; CLOSOSKI, GIULIANO CESAR - FCFRP
- Unidade: FCFRP
- DOI: 10.1111/bph.12717
- Subjects: HIPOTERMIA; HIPOTÁLAMO; FARMACOLOGIA
- Language: Inglês
- Imprenta:
- Publisher place: West Sussex
- Date published: 2014
- Source:
- Título: British Journal of Pharmacology
- ISSN: 0007-1188
- Volume/Número/Paginação/Ano: v. 171, n. 15, p. 3666-3679, 2014
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: green
-
ABNT
MALVAR, David do C. et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PG'E IND.2'-dependent and -independent fever while 4-AA only blocks PG'E IND.2'-dependent fever. British Journal of Pharmacology, v. 171, n. 15, p. 3666-3679, 2014Tradução . . Disponível em: https://doi.org/10.1111/bph.12717. Acesso em: 28 dez. 2025. -
APA
Malvar, D. do C., Aguiar, F. A., Vaz, A. de L. L., Assis, D. C. R., Melo, M. C. C. de, Jabor, V. A. P., et al. (2014). Dipyrone metabolite 4-MAA induces hypothermia and inhibits PG'E IND.2'-dependent and -independent fever while 4-AA only blocks PG'E IND.2'-dependent fever. British Journal of Pharmacology, 171( 15), 3666-3679. doi:10.1111/bph.12717 -
NLM
Malvar D do C, Aguiar FA, Vaz A de LL, Assis DCR, Melo MCC de, Jabor VAP, Kalapothakis E, Ferreira SH, Clososki GC, Souza GEP de. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PG'E IND.2'-dependent and -independent fever while 4-AA only blocks PG'E IND.2'-dependent fever [Internet]. British Journal of Pharmacology. 2014 ; 171( 15): 3666-3679.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1111/bph.12717 -
Vancouver
Malvar D do C, Aguiar FA, Vaz A de LL, Assis DCR, Melo MCC de, Jabor VAP, Kalapothakis E, Ferreira SH, Clososki GC, Souza GEP de. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PG'E IND.2'-dependent and -independent fever while 4-AA only blocks PG'E IND.2'-dependent fever [Internet]. British Journal of Pharmacology. 2014 ; 171( 15): 3666-3679.[citado 2025 dez. 28 ] Available from: https://doi.org/10.1111/bph.12717 - Determination of dipyrone active metabolites in rat hypothalamus samples using liquid chromatography tandem mass spectrometry (LC-MS-MS)
- Antipyretic effect and central nervous system amount of dipyrone active metabolites, 4-methylaminoantipyrine (4-MAA) and 4-aminoantipyrine (4-AA)
- Reparixin, via CXCR1/CXCR2, does not reduce fever induced by PGE2 mediators
- Antipyretic effect of ibuprofen on LPS-induced fever is not related to cytokines synthesis inhibition
- The relevance of kalikrein-kinin system via activation of B2 receptor in LPS-induced fever in rats
- Cytokine-induced neutrophil chemoattractant (GINC)-1 induces fever by a prostaglandin-dependent mechanism in rats
- Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin 'V IND. 1' receptors
- Involvement of PG'E IND.2' and RANTES in Staphylococcus aureus-induced fever in rats
- Chemokine ligand (CCL)-3 promotes an integrated febrile response when injected within pre-optic area (POA) of rats and induces calcium signaling in cells of POA microcultures but not TNF-α or IL-6 synthesis
- Simultaneous determination of dipyrone metabolites in three significant rats biological matrices by liquid chromatography tandem mass spectrometry
Informações sobre o DOI: 10.1111/bph.12717 (Fonte: oaDOI API)
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