(+)'alfa'-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex 1 and is as effective as arsenic trioxide or ATRA against promyelocytic Leukemia in vivo (2012)
- Authors:
- Santos, G. A. S.
- Abreu e Lima, R. S.
- Pestana, C. R.
- Lima, A. S. G.
- Scheucher, P. S.
- Thomé, C. H.
- Gimenes Teixeira, H. L.
- Santana-Lemos, Bárbara Amélia Aparecida
- Lucena-Araújo, A. R.
- Rodrigues, F. P.
- Nasr, R.
- Uyemura, Sérgio Akira
- Falcao, Roberto Passetto
- Thé, H. de
- Pandolfi, P. P.
- Curti, Carlos
- Rego, Eduardo Magalhaes
- USP affiliated authors: LEMOS, BÁRBARA AMÉLIA APARECIDA SANTANA - FMRP ; UYEMURA, SERGIO AKIRA - FCFRP ; FALCÃO, ROBERTO PASSETTO - FMRP ; CURTI, CARLOS - FCFRP ; REGO, EDUARDO MAGALHÃES - FMRP
- Unidades: FMRP; FCFRP
- DOI: 10.1038/leu.2011.216
- Subjects: ANTINEOPLÁSICOS (FARMACOLOGIA;APLICAÇÕES TERAPÊUTICAS); ANTIOXIDANTES; APOPTOSE (EFEITOS DE DROGAS); MODELOS ANIMAIS DE DOENÇAS; TRANSPORTE DE ELÉTRONS (ANTAGONISTAS E INIBIDORES); LEUCEMIA; MITOCÔNDRIAS (EFEITOS DE DROGAS)
- Language: Inglês
- Imprenta:
- Source:
- Este periódico é de acesso aberto
- Este artigo NÃO é de acesso aberto
-
ABNT
SANTOS, G. A. S. et al. (+)'alfa'-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex 1 and is as effective as arsenic trioxide or ATRA against promyelocytic Leukemia in vivo. Leukemia, v. 26, n. 3, p. 451-460, 2012Tradução . . Disponível em: https://doi.org/10.1038/leu.2011.216. Acesso em: 24 jan. 2026. -
APA
Santos, G. A. S., Abreu e Lima, R. S., Pestana, C. R., Lima, A. S. G., Scheucher, P. S., Thomé, C. H., et al. (2012). (+)'alfa'-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex 1 and is as effective as arsenic trioxide or ATRA against promyelocytic Leukemia in vivo. Leukemia, 26( 3), 451-460. doi:10.1038/leu.2011.216 -
NLM
Santos GAS, Abreu e Lima RS, Pestana CR, Lima ASG, Scheucher PS, Thomé CH, Gimenes Teixeira HL, Santana-Lemos BAA, Lucena-Araújo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcao RP, Thé H de, Pandolfi PP, Curti C, Rego EM. (+)'alfa'-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex 1 and is as effective as arsenic trioxide or ATRA against promyelocytic Leukemia in vivo [Internet]. Leukemia. 2012 ; 26( 3): 451-460.[citado 2026 jan. 24 ] Available from: https://doi.org/10.1038/leu.2011.216 -
Vancouver
Santos GAS, Abreu e Lima RS, Pestana CR, Lima ASG, Scheucher PS, Thomé CH, Gimenes Teixeira HL, Santana-Lemos BAA, Lucena-Araújo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcao RP, Thé H de, Pandolfi PP, Curti C, Rego EM. (+)'alfa'-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex 1 and is as effective as arsenic trioxide or ATRA against promyelocytic Leukemia in vivo [Internet]. Leukemia. 2012 ; 26( 3): 451-460.[citado 2026 jan. 24 ] Available from: https://doi.org/10.1038/leu.2011.216 - The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated
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Informações sobre o DOI: 10.1038/leu.2011.216 (Fonte: oaDOI API)
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