Artigo de periodico

Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women (2010)

• Authors:
  • Simbalista, Renée Leão
  • Sauerbronn, Adolfo V
  • Aldrighi, José Mendes
  • Arêas, José Alfredo Gomes
• USP affiliated authors: ALDRIGHI, JOSÉ MENDES - FSP ; AREAS, JOSE ALFREDO GOMES - FSP
• Unidade: FSP
• Subjects: CLIMATÉRIO; SINAIS E SINTOMAS (ASSOCIAÇÃO;AVALIAÇÃO); CONSUMO DE ALIMENTOS (ASSOCIAÇÃO;AVALIAÇÃO); PÃO (MEDIDAS); LINHO (MEDIDAS); TRIGO (MEDIDAS); LIPÍDEOS (SANGUE;ANÁLISE); ESTUDOS DE CASOS E CONTROLES
• Agências de fomento:
  • Financiado pela FAPESP
• Language: Inglês
• Abstract: Our objective in this work was to test the effects of daily intake of bread produced with partially defatted ground flaxseed on the climacteric symptoms and endometrial thickness of postmenopausal women. A double-blind, placebo-controlled, randomized clinical trial was performed with 38 women who had been postmenopausal for 1–10 y and consumed 2 slices of bread containing 25 g of flaxseed (46 mg lignans) or wheat bran (<1 mg lignans; control) every day for 12 consecutive weeks. The outcome variables were the daily number of hot flashes, the Kupperman Menopausal Index (KMI), and endometrial thickness. The plasma lipid profile (total cholesterol and HDL, LDL, and VLDL cholesterol fractions and triglycerides) and the hormones estradiol, follicle-stimulating hormone, thyroid-stimulating hormone, and free thyroxine also were measured. Food intake was evaluated by means of 2 24-h recalls, before and after the treatment. Twenty patients in the study group and 18 in the control group completed the study. The general characteristics did not differ between the 2 groups at the start of the study. Both had significant, but similar, reductions in hot flashes and KMI after 3 mo of treatment. Moreover, endometrial thickness was not affected in either group. Our findings clearly show that although flaxseed is safe, its consumption at this level (46 mg lignans/d) is no more effective than placebo for reducing hot flashes and KMI
• Imprenta:
  • Publisher place: Philadelphia
  • Date published: 2010
• Source:
  • Título: The Journal of Nutrition
  • ISSN: 0022-3166
  • Volume/Número/Paginação/Ano: n. 140, p. 293 - 297, Feb. 2010


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How to cite

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• ABNT

  SIMBALISTA, Renée Leão et al. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women. The Journal of Nutrition, n. 140, p. 293 - 297, 2010Tradução . . Disponível em: https://academic.oup.com/jn/article/140/2/293/4600315. Acesso em: 28 dez. 2025.

• APA

  Simbalista, R. L., Sauerbronn, A. V., Aldrighi, J. M., & Arêas, J. A. G. (2010). Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women. The Journal of Nutrition, ( 140), 293 - 297. Recuperado de https://academic.oup.com/jn/article/140/2/293/4600315

• NLM

  Simbalista RL, Sauerbronn AV, Aldrighi JM, Arêas JAG. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women [Internet]. The Journal of Nutrition. 2010 ;( 140): 293 - 297.[citado 2025 dez. 28 ] Available from: https://academic.oup.com/jn/article/140/2/293/4600315

• Vancouver

  Simbalista RL, Sauerbronn AV, Aldrighi JM, Arêas JAG. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women [Internet]. The Journal of Nutrition. 2010 ;( 140): 293 - 297.[citado 2025 dez. 28 ] Available from: https://academic.oup.com/jn/article/140/2/293/4600315

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