Rational anti-chagasic drug design based on the structure of trypanosoma cruzi dihydroorotate dehydrogenase (2009)
- Authors:
- USP affiliated authors: MONTANARI, CARLOS ALBERTO - IQSC ; COSTA, MARIA CRISTINA NONATO - FCFRP
- Unidades: IQSC; FCFRP
- Subjects: TRYPANOSOMA CRUZI (ESTRUTURA); CRISTALOGRAFIA; PLANEJAMENTO DE FÁRMACOS
- Language: Inglês
- Imprenta:
- Publisher place: Águas de Lindóia
- Date published: 2009
- Source:
- Título: Program and Index
- Volume/Número/Paginação/Ano: 2009
- Conference titles: Annual Meeting of the Brazilian Society for biochemistry and molecular biology - SBBq
-
ABNT
PINHEIRO, M. P. et al. Rational anti-chagasic drug design based on the structure of trypanosoma cruzi dihydroorotate dehydrogenase. 2009, Anais.. Águas de Lindóia: Instituto de Química de São Carlos, Universidade de São Paulo, 2009. . Acesso em: 31 dez. 2025. -
APA
Pinheiro, M. P., Rocha, F. R., Montanari, C. A., & Nonato, M. C. (2009). Rational anti-chagasic drug design based on the structure of trypanosoma cruzi dihydroorotate dehydrogenase. In Program and Index. Águas de Lindóia: Instituto de Química de São Carlos, Universidade de São Paulo. -
NLM
Pinheiro MP, Rocha FR, Montanari CA, Nonato MC. Rational anti-chagasic drug design based on the structure of trypanosoma cruzi dihydroorotate dehydrogenase. Program and Index. 2009 ;[citado 2025 dez. 31 ] -
Vancouver
Pinheiro MP, Rocha FR, Montanari CA, Nonato MC. Rational anti-chagasic drug design based on the structure of trypanosoma cruzi dihydroorotate dehydrogenase. Program and Index. 2009 ;[citado 2025 dez. 31 ] - Virtual screening, calorimetric assays and x-ray crystallography for Trypanosoma cruzi DHOH inhibitors discovery
- Search for inhibitors of dihydroorotate dehydrogenase from Trypanosoma cruzi
- Novel insights for patent dihydroorotate dehydrogenase class 1A inhibitors discovery
- Isothermal titration calorimetry as a tool for determining kinetic parameters of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme
- Kinetic mechanism and catalysis of Trypanossoma cruzi dihydroorotate dehydrogenase enzyme evaluated by isothermal titration calorimetry
- Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery
- Heterologous expression and kinetic analysis of recombinant fumarate hydratase from Leishmania major
- Functional characterization of Leishmania major dihydroorotate dehydrogenase
- Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain
- Preliminary structural characterization of Trypanosoma cruzi fumarate hydratase
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