Prevalence of endometrial cancer and hyperplasia in non-symptomatic overweight and obese women (2008)
- Authors:
- Autor USP: ALDRIGHI, JOSE MENDES - FSP
- Unidade: FSP
- DOI: 10.1111/j.1479-828x.2008.00845.x
- Subjects: NEOPLASIAS; ENDOMÉTRIO; HIPERPLASIAS; OBESIDADE; PESOS E MEDIDAS CORPORAIS
- Language: Inglês
- Abstract: Background: Obesity is a public health problem and it is necessary to identify if non-symptomatic obese women must be submitted to endometrial evaluation. Aims: To determine the prevalence of endometrial hyperplasia and cancer in non-symptomatic overweight or obese women. Methods: A cross-sectional study was carried out in 193 women submitted to an endometrial biopsy using a Pipelle de Cornier. The findings were classified as normal, hyperplasia or cancer, and the results were compared to body mass index (BMI; kg/m2). For the purpose of statistical analysis, women were divided into two groups: women of reproductive age and postmenopausal women, and according to BMI as overweight or obese. Results: The prevalence of endometrial cancer and hyperplasia was 1.0% and 5.8% in women of reproductive age and 3.0% and 12.1% in postmenopausal women, respectively. According to logistic regression, being in the postmenopause increased the risk of endometrial hyperplasia and cancer to 1.19 (95% confidence interval (CI): 0.36-3.90), while being postmenopausal and severely obese increased the odds ratio (OR) to 1.58 (95%CI: 0.30-8.23) and being postmenopausal and morbidly obese increased the OR to 2.72 (95%CI: 0.65-11.5). No increase in risk was found in women of reproductive age who were either overweight or obese. Discussion: Our results show that non-symptomatic, severe or morbidly obese postmenopausal women have a high risk of developing endometrial hyperplasia or cancer;however, no such risk was found for women of reproductive age.
- Imprenta:
- Source:
- Título do periódico: The Australian and New Zealand Journal of Obstetrics and Gynaecology
- ISSN: 0004-8666
- Volume/Número/Paginação/Ano: v. 48, n. 2, p. 207-213, Apr. 2008
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
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ABNT
VIOLA, Alexandre S. et al. Prevalence of endometrial cancer and hyperplasia in non-symptomatic overweight and obese women. The Australian and New Zealand Journal of Obstetrics and Gynaecology, v. 48, n. 2, p. 207-213, 2008Tradução . . Disponível em: https://doi.org/10.1111/j.1479-828x.2008.00845.x. Acesso em: 24 set. 2024. -
APA
Viola, A. S., Gouveia, D., Andrade, L., Aldrighi, J. M., Viola, C. F. M., & Bahamondes, L. (2008). Prevalence of endometrial cancer and hyperplasia in non-symptomatic overweight and obese women. The Australian and New Zealand Journal of Obstetrics and Gynaecology, 48( 2), 207-213. doi:10.1111/j.1479-828x.2008.00845.x -
NLM
Viola AS, Gouveia D, Andrade L, Aldrighi JM, Viola CFM, Bahamondes L. Prevalence of endometrial cancer and hyperplasia in non-symptomatic overweight and obese women [Internet]. The Australian and New Zealand Journal of Obstetrics and Gynaecology. 2008 ; 48( 2): 207-213.[citado 2024 set. 24 ] Available from: https://doi.org/10.1111/j.1479-828x.2008.00845.x -
Vancouver
Viola AS, Gouveia D, Andrade L, Aldrighi JM, Viola CFM, Bahamondes L. Prevalence of endometrial cancer and hyperplasia in non-symptomatic overweight and obese women [Internet]. The Australian and New Zealand Journal of Obstetrics and Gynaecology. 2008 ; 48( 2): 207-213.[citado 2024 set. 24 ] Available from: https://doi.org/10.1111/j.1479-828x.2008.00845.x - Comparison between raloxifene and hormone replacement therapy on ambulatory blood pressure and arterial stiffness
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Informações sobre o DOI: 10.1111/j.1479-828x.2008.00845.x (Fonte: oaDOI API)
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