Spread of methicillin-resistant Staphylococcis aureus clone isolated from bacteremia in elderly patients in a Brazilian general hospital (2007)
- Authors:
- Autor USP: DARINI, ANA LUCIA DA COSTA - FCFRP
- Unidade: FCFRP
- Subjects: EPIDEMIOLOGIA; HOSPITAIS GERAIS; STAPHYLOCOCCUS; RESISTÊNCIA; IDOSOS
- Language: Inglês
- Abstract: A study of the genomic diversity of MRSA strains isolated from elderly patients with infection/colonization in three repeated prevalence, cross sectional studies was performed in the 1999-2000 period. In this study, 13 MRSA isolates from blood cultures and 5 from rectal and nare cultures were obtained from 18 patients (13 elderly and 5 adults). Most of the patients were being treated with two or more antimicrobials (83.3%), had insertion of invasive devices (88.9%) and were managed in ICU (Intensive Care Unit) and/ or surgical units (66.7%). MIC Minimum Inhibitory Concentration) data showed that 88.9% of the MRSA strains were resistant to high concentrations of oxacillin (MIC '>OU=' 256 'mu'g/mL), 94.5% of the MRSA carried the mecA gene in their genome, and most (65.0%) of the isolates were indistinguishable according to their DNA finger printing generated by PFGE (Pulsed-field gel electrophoresis). Although PFGE typing was performed with a few MRSA isolates, our results demonstrate that one MRSA clone was associated with infection/colonization in patients with an obvious connection among five out of eleven patients who stayed in the same clinic and ICU during the same period. Hospital acquired infection, a major "silent epidemy", is associated with prolonged hospital stay and high mortality rate and its cause must be better evaluated
- Imprenta:
- Publisher place: Washington
- Date published: 2007
- Source:
- Título: Antimicrobial Agents and Chemotherapy
- ISSN: 1679-7140
- Volume/Número/Paginação/Ano: v. 51, n. 1, p. 401-402, 2007
-
ABNT
RIBAS, Rosineide Marques et al. Spread of methicillin-resistant Staphylococcis aureus clone isolated from bacteremia in elderly patients in a Brazilian general hospital. Antimicrobial Agents and Chemotherapy, v. 51, n. 1, p. 401-402, 2007Tradução . . Acesso em: 21 jan. 2026. -
APA
Ribas, R. M., Darini, A. L. da C., Ferreira, J. C., Freitas, C., & Gontijo filho, P. (2007). Spread of methicillin-resistant Staphylococcis aureus clone isolated from bacteremia in elderly patients in a Brazilian general hospital. Antimicrobial Agents and Chemotherapy, 51( 1), 401-402. -
NLM
Ribas RM, Darini AL da C, Ferreira JC, Freitas C, Gontijo filho P. Spread of methicillin-resistant Staphylococcis aureus clone isolated from bacteremia in elderly patients in a Brazilian general hospital. Antimicrobial Agents and Chemotherapy. 2007 ; 51( 1): 401-402.[citado 2026 jan. 21 ] -
Vancouver
Ribas RM, Darini AL da C, Ferreira JC, Freitas C, Gontijo filho P. Spread of methicillin-resistant Staphylococcis aureus clone isolated from bacteremia in elderly patients in a Brazilian general hospital. Antimicrobial Agents and Chemotherapy. 2007 ; 51( 1): 401-402.[citado 2026 jan. 21 ] - Relationship between nasal colonization and ventilator-associated pneumonia and the role of the environment in transmission of Staphylococcus aureus in intensive care units
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