Artigo de periodico

Prospective study of hepatitis C virus infection in hemodialysis patients by monthly analysis of HCV RNA and antibodies (2003)

• Authors:
  • Pinho, João Renato Rebello
  • Fares, Jorge Alexandre
  • Oba, Isabel Takano
  • Cardoso, Maria Regina Alves
  • Saraceni, Cláudia Patara
  • Granato, Celso
• Autor USP: CARDOSO, MARIA REGINA ALVES - FSP
• Unidade: FSP
• DOI: 10.1139/w03-065
• Subjects: HEPATITE C; TERAPIA DE SUBSTITUIÇÃO RENAL; REAÇÃO EM CADEIA POR POLIMERASE; VÍRUS DA HEPATITE C (GENÉTICA)
• Language: Inglês
• Abstract: Abstract: The aims of this study were to (i) evaluate the prevalence and the incidence of hepatitis C virus (HCV) infection in hemodialysis patients in two different centers in São Paulo (Brazil), (ii) determine the time required to detect HCV infection among these patients by serology or PCR, (iii) establish the importance of alanine aminotransferase determination as a marker of HCV infection, and (iv) identify the HCV genotypes in this population. Serum samples were collected monthly for 1 year from 281 patients admitted to hospital for hemodialysis. Out of 281 patients, 41 patients (14.6 percent) were HCV positive; six patients seroconverted during this study (incidence=3.1/1000 person-month). In 1.8 percent (5/281) of cases, RNA was detected before the appearance of antibodies (up to 5 months), and in 1.1 percent (3/281) of cases, RNA was the unique marker of HCV infection. The genotypes found were 1a, 1b, 3a, and 4a. The presence of genotype 4a is noteworthy, since it is a rare genotype in Brazil. These data pointed out the high prevalence and incidence of HCV infection at hemodialysis centers in Brazil and showed that routine PCR is fundamental for improving the detection of HCV carriers among patients undergoing hemodialysis
• Imprenta:
  • Publisher place: Ottawa
  • Date published: 2003
• Source:
  • Título: Canadian Journal of Microbiology
  • ISSN: 1480-3275
  • Volume/Número/Paginação/Ano: v. 49, n. 8, p. 503-507, 2003

Informações sobre o DOI: 10.1139/w03-065 (Fonte: oaDOI API)
• Este periódico é de acesso aberto
• Este artigo NÃO é de acesso aberto
  

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How to cite

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• ABNT

  PINHO, João Renato Rebello et al. Prospective study of hepatitis C virus infection in hemodialysis patients by monthly analysis of HCV RNA and antibodies. Canadian Journal of Microbiology, v. 49, n. 8, p. 503-507, 2003Tradução . . Disponível em: https://doi.org/10.1139/w03-065. Acesso em: 21 fev. 2026.

• APA

  Pinho, J. R. R., Fares, J. A., Oba, I. T., Cardoso, M. R. A., Saraceni, C. P., & Granato, C. (2003). Prospective study of hepatitis C virus infection in hemodialysis patients by monthly analysis of HCV RNA and antibodies. Canadian Journal of Microbiology, 49( 8), 503-507. doi:10.1139/w03-065

• NLM

  Pinho JRR, Fares JA, Oba IT, Cardoso MRA, Saraceni CP, Granato C. Prospective study of hepatitis C virus infection in hemodialysis patients by monthly analysis of HCV RNA and antibodies [Internet]. Canadian Journal of Microbiology. 2003 ; 49( 8): 503-507.[citado 2026 fev. 21 ] Available from: https://doi.org/10.1139/w03-065

• Vancouver

  Pinho JRR, Fares JA, Oba IT, Cardoso MRA, Saraceni CP, Granato C. Prospective study of hepatitis C virus infection in hemodialysis patients by monthly analysis of HCV RNA and antibodies [Internet]. Canadian Journal of Microbiology. 2003 ; 49( 8): 503-507.[citado 2026 fev. 21 ] Available from: https://doi.org/10.1139/w03-065

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