In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT

In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT (2004)

Authors:
USP affiliated authors: COLQUHOUN, ALISON - ICB ; BELIZARIO, JOSE ERNESTO - ICB
Unidade: ICB
Subjects: HISTOLOGIA; FARMACOLOGIA
Language: Inglês
Abstract: The initial breach of the outer mitochondrial membrane may appear literally punctual and openings of this membrane in the range of ~ 30, ~ 50 and ~ 100 nm are observable. To cover the expanding swollen matrix the inner membrane utilizes membrane organized in the cristae. The initial small sized aperture of the outer membrane is preceded by a localized intermembranous swelling. The initial small sized aperture of the outer mitochondrial membrane correlates, with the immunoelectronmicroscopic demonstration of clusters of particles signaling the presence of Bax molecules tightly adhering to restrict segments of the outer membrane in apoptotic cells (Nechushtan et al. J C Biol 153,1265, 2001; de Giorgi et al. FASEB J ,16, 607, 2002). In the majority of culture experiments (n = 24) the percentage of cells with normal nuclei and expressing MPT varied from 1 to 24%, these percentages correlated positively (n=37 r2 = 0.60; p< 0.0001) with the percentage of cells of the same culture with apoptotic nuclei
Imprenta:
- Publisher place: Campinas
- Date published: 2004
Source:
- Título: Abstracts
Conference titles: Congress of the Brazilian Society for Cell Biology

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ABNT

SESSO, Antonio et al. In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT. 2004, Anais.. Campinas: Instituto de Ciências Biomédicas, Universidade de São Paulo, 2004. . Acesso em: 27 jan. 2026.
APA

Sesso, A., Marques, M. M., Monteiro, M. M. T., Schumacher, R. I., Colquhoun, A., Belizário, J. E., et al. (2004). In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT. In Abstracts. Campinas: Instituto de Ciências Biomédicas, Universidade de São Paulo.
NLM

Sesso A, Marques MM, Monteiro MMT, Schumacher RI, Colquhoun A, Belizário JE, Konno SN, Felix TB, Botelho LAA, Santos VZC, Silva GR da, Higuchi M de L, Hito ES, Kawakami JT. In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT. Abstracts. 2004 ;[citado 2026 jan. 27 ]
Vancouver

Sesso A, Marques MM, Monteiro MMT, Schumacher RI, Colquhoun A, Belizário JE, Konno SN, Felix TB, Botelho LAA, Santos VZC, Silva GR da, Higuchi M de L, Hito ES, Kawakami JT. In the early stages of the mitochondrial permeability transition (MPT) the rupture of outer membrane is small sized. Correlation between apoptotic indices and MPT. Abstracts. 2004 ;[citado 2026 jan. 27 ]