Trabalho de evento-resumo

Study of nasal mudus in patients with cleft lip and palate (2001)

• Authors:
  • Trindade, Sergio Henrique Kiemle
  • Guimarães, E. T.
  • Macchione, Mariangela
  • Trindade, Inge Elly Kiemle
  • Lorenzi Filho, Geraldo
  • Saldiva, Paulo Hilário Nascimento
• USP affiliated authors: TRINDADE, INGE ELLY KIEMLE - FOB ; SALDIVA, PAULO HILARIO NASCIMENTO - FM ; LORENZI FILHO, GERALDO - FM ; MACCHIONE, MARIANGELA - FM
• Unidades: FOB; FM
• Subjects: FISSURA LÁBIOPALATINA; OTORRINOLARINGOLOGIA
• Agências de fomento:
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
  • Financiamento CNPq
• Language: Inglês
• Abstract: Patients with deft lip and palate (CLP) present a high incidence of upper airway infections. The observation of a decreased in vivo mucociliary clearance suggests that this is a mechanism involved in the genesis of upper airway infections. Changes in mucociliary transport can be related to alterations in the cilia, mucus or its interaction. The objective of this study was to compare the nasal mucus transportability and physical properties of patients with CLP to the mucus of normal subjects. The mucus of 31 patients with CLP and 16 of normal subjects was collected by nasal aspiration. In vitro mucus transportability (MT) by cilia was evaluated by the method of the frog palate (results are expressed as relative speed). Cough clearence (CC) was evaluated by the method of simulated cough machine (results are expressed in mm). Mucus physical properties were evaluated by the contact angle (CA), by measuring the angle (in degrees) between the mucus sample and a glass surface. Mucus rheologic properties were determined by means of a magnetic rheometer, and the results are expressed as log G' (vectorial sum of viscosity and elasticity) and Tan del (relationship between viscosity and elasticityl measured at 1 and 1 00 rad/s. The results for the normal and CLP groups, expressed as mean ± standard deviation (*, p< 0,05) were, respectively: MT= 0.87±0.29 and 0.85+0.39; CC(mm)= 41±24 and 65±32'; CA(degrees)= 35±11 and 24±15*; 10g G'I= 1.43±0.4 and 1.52±0.71; Tan dell- 0.42±0.1 and 0.49±0.24; 10g G'JOO= 1.52±0.28 and 1.53±0.S8; Tan dell 100= 0.51±0.12 and 0.72±0.23'. The results suggest that patients with CLP have a higher transportability by cough when compared to normal subjects. The inccreased number of upper airway infections in these patients cannot be explained by changes in mucus physical properties and transportability.
• Imprenta:
  • Publisher: HRAC-USP
  • Publisher place: Bauru
  • Date published: 2001
• Source:
  • Título: Anais do IV Encontro Científico de Pós-Graduação HRAC-USP "Prof. Dr. Celso Amauri Cerigatto"
• Conference titles: Encontro Científico da Pós-Graduação do HRAC-USP

---

Download do texto completo

Tipo	Nome	Link
	1231123.pdf

How to cite

A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas

• ABNT

  TRINDADE, Sergio Henrique Kiemle et al. Study of nasal mudus in patients with cleft lip and palate. 2001, Anais.. Bauru: HRAC-USP, 2001. Disponível em: https://repositorio.usp.br/directbitstream/537fe9e1-88b1-437c-9989-40302b882fa0/1231123.pdf. Acesso em: 02 out. 2024.

• APA

  Trindade, S. H. K., Guimarães, E. T., Macchione, M., Trindade, I. E. K., Lorenzi Filho, G., & Saldiva, P. H. N. (2001). Study of nasal mudus in patients with cleft lip and palate. In Anais do IV Encontro Científico de Pós-Graduação HRAC-USP "Prof. Dr. Celso Amauri Cerigatto". Bauru: HRAC-USP. Recuperado de https://repositorio.usp.br/directbitstream/537fe9e1-88b1-437c-9989-40302b882fa0/1231123.pdf

• NLM

  Trindade SHK, Guimarães ET, Macchione M, Trindade IEK, Lorenzi Filho G, Saldiva PHN. Study of nasal mudus in patients with cleft lip and palate [Internet]. Anais do IV Encontro Científico de Pós-Graduação HRAC-USP "Prof. Dr. Celso Amauri Cerigatto". 2001 ;[citado 2024 out. 02 ] Available from: https://repositorio.usp.br/directbitstream/537fe9e1-88b1-437c-9989-40302b882fa0/1231123.pdf

• Vancouver

  Trindade SHK, Guimarães ET, Macchione M, Trindade IEK, Lorenzi Filho G, Saldiva PHN. Study of nasal mudus in patients with cleft lip and palate [Internet]. Anais do IV Encontro Científico de Pós-Graduação HRAC-USP "Prof. Dr. Celso Amauri Cerigatto". 2001 ;[citado 2024 out. 02 ] Available from: https://repositorio.usp.br/directbitstream/537fe9e1-88b1-437c-9989-40302b882fa0/1231123.pdf

Últimas obras dos mesmos autores vinculados com a USP cadastradas na BDPI:

• Study of nasal mucus in patients with cleft lip and palate
• Effects of n-propil gallato on the frog palate mucocilliary epithelium injury by hydrogen peroxide
• A noninvasive method of sampling human tracheal mucus
• Efeitos do manitol inalatório sobre o epitélio ciliado do palato de rã
• Estudo do efeito da deferoxamina no epitélio mucociliar de palato de rã como inibidor das alterações induzidas por material particulado urbano (PM10)
• O uso da casca da caesalpinia pelthophoroides como bio-indicador da concentação de material particulado atmosférico
• Methods for studying mucociliary transport
• Avaliação do estresse oxidativo induzido por partículas do ar ambiente com Escherichia coli abrigando uma fusão katG'::lacZ
• Amostragem Passiva como Alternativa na Determinação da Concentração de Ozônio na Cidade de São Paulo
• Effects of hypertonic saline solution on the ciliated epithelium of the frog palate