Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis

Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis (2000)

Authors:
- Silva, V. A.
- Chadi, Gerson
USP affiliated authors: CHADI, GERSON - ICB ; MARKUS, REGINA PEKELMANN - IB
Unidades: ICB; IB
Subjects: ANATOMIA
Language: Inglês
Abstract: (continuation) More astrocytes and microglia were found in cochlear (140% and 163%, respectively) and lateral superior olivary nuclei (87% and 148%, respectively) after the treatments. Increased (35%) bFGF imunoreactivity was found in SG neurons ofthe gentamycin treated P15 offspring. bFGF was also increased in the glial cell nuclei of the CN (93%) and LSO (143%) of groups treated with gentamycin.Conclusões: The gentamycin-induced hearing loss can trigger cell death and glial changes inthe cochlea and auditory pathways. The glial rection and the regulation of the bFGF in these regions following gentamycin treatment may represent adaptive response to the lesion
Imprenta:
- Publisher: FESBE
- Place of publication: São Paulo
- Date published: 2000
Source:
- Título do periódico: Resumos
Conference title: Reunião Anual da Federação de Sociedades de Biologia Experimental

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ABNT

SILVA, V. A.; CHADI, Gerson. Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis. Anais.. São Paulo: FESBE, 2000.
APA

Silva, V. A., & Chadi, G. (2000). Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis. In Resumos. São Paulo: FESBE.
NLM

Silva VA, Chadi G. Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis. Resumos. 2000 ;
Vancouver

Silva VA, Chadi G. Glial reaction and trophic response in the cochlea and central auditory pathways after gentamycin induced ototoxicity in neonatal rat: An immunohistochemical study combined to computer assisted stereology an image analysis. Resumos. 2000 ;