PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma

PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma (1999)

Authors:
USP affiliated authors: ARAUJO, NEY SOARES DE - FO ; PINTO JUNIOR, DECIO DOS SANTOS - FO ; ARAUJO, VERA CAVALCANTI DE - FO
School: FO
DOI: 10.1111/j.1600-0714.1999.tb02103.x
Subjects: PATOLOGIA BUCAL; CARCINOMA DE CÉLULAS ESCAMOSAS
Language: Inglês
Abstract: This study was performed on oral squamous cell carcinomas (OSCC) in order to investigate the relation between the number of interphase silver-stained nucleolar organizer regions (AgNORs) and the immunolabeling of proliferation-associated markers, using antibodies to Ki-67 and proliferating cell nuclear antigen (PCNA). Fifteen consecutive cases of oral squamous cell carcinoma were used and a double staining technique was permormed in order to quantify the number of NORs in PCNA-positive and -negative cells as well as in Ki-67-positive and -negative cells. Our results showed a higher mean number of AgNors in PCNA-and Ki67-positive cells than in PCNA- and Ki-67-negative cells. We concluded that there is an association between cell proliferation and AgNOR score in OSCC
Imprenta:
- Place of publication: Copenhagen
- Date published: 1999
Source:
- Título do periódico: Journal Oral Pathology e Medicine
- Volume/Número/Paginação/Ano: v. 28, n. 10, p. 438-441, Nov. 1999

Informações sobre o DOI: 10.1111/j.1600-0714.1999.tb02103.x (Fonte: oaDOI API)

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ABNT

COSTA, Antonio de Lisboa Lopes; ARAÚJO, Ney Soares de; PINTO JÚNIOR, Décio dos Santos; ARAÚJO, Vera Cavalcanti de. PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma. Journal Oral Pathology e Medicine, Copenhagen, v. No 1999, n. 10, p. 438-441, 1999. DOI: 10.1111/j.1600-0714.1999.tb02103.x.
APA

Costa, A. de L. L., Araújo, N. S. de, Pinto Júnior, D. dos S., & Araújo, V. C. de. (1999). PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma. Journal Oral Pathology e Medicine, No 1999( 10), 438-441. doi:10.1111/j.1600-0714.1999.tb02103.x
NLM

Costa A de LL, Araújo NS de, Pinto Júnior D dos S, Araújo VC de. PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma. Journal Oral Pathology e Medicine. 1999 ; No 1999( 10): 438-441.
Vancouver

Costa A de LL, Araújo NS de, Pinto Júnior D dos S, Araújo VC de. PCNA/AgNOR and Ki-67/AgNOR double staining in oral squamous cell carcinoma. Journal Oral Pathology e Medicine. 1999 ; No 1999( 10): 438-441.