Yerba Maté (Ilex paraguariensis) aqueous extract decreases intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic wistar rats (2008)
- Authors:
- Autor USP: BASTOS, DEBORAH HELENA MARKOWICZ - FSP
- Unidade: FSP
- Subjects: MATE (PROPRIEDADES;APLICAÇÕES TERAPÊUTICAS); DIABETES MELLITUS (CONTROLE); EXPRESSÃO GÊNICA; RATOS
- Language: Inglês
- Abstract: Yerba mate´ (Ilex paraguariensis) is rich in polyphenols, especially chlorogenic acids. Evidence suggests that dietary polyphenols could play a role in glucose absorption and metabolism. The aim of this study was to evaluate the antidiabetic properties of yerba mate´ extract in alloxan-induced diabetic Wistar rats. Animals (n ) 41) were divided in four groups: nondiabetic control (NDC, n=11), and diabetic yerba maté (DY, n = 10). The intervention consisted in the administration of yerba mate´ extract in a 1 g extract/ kg body weight dose for 28 days; controls received saline solution only. There were no significant differences in serum glucose, insulin, and hepatic glucose-6-phosphatase activity between the groups that ingested yerba maté extract (NDY and DY) and the controls (NDC and DC). However, the intestinal SGLT1 gene expression was significantly lower in animals that received yerba maté both in upper (p = 0.007) and middle (p < 0.001) small intestine. These results indicate that bioactive compounds present in yerba maté might be capable of interfering in glucose absorption, by decreasing SGLT1 expression
- Imprenta:
- Source:
- Título do periódico: Journal of Agricultural and Food Chemistry
- ISSN: 0021-8561
- Volume/Número/Paginação/Ano: v. 56, n. 22, p. 10527-10532, Feb. 2009
-
ABNT
OLIVEIRA, Daniela M. et al. Yerba Maté (Ilex paraguariensis) aqueous extract decreases intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic wistar rats. Journal of Agricultural and Food Chemistry, v. 56, n. 22, p. 10527-10532, 2008Tradução . . Acesso em: 24 abr. 2024. -
APA
Oliveira, D. M., Freitas, H. S. de, Souza, M. F. F., Arçari, D. P., Ribeiro, M. L., Carvalho, P. de O., & Bastos, D. H. M. (2008). Yerba Maté (Ilex paraguariensis) aqueous extract decreases intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic wistar rats. Journal of Agricultural and Food Chemistry, 56( 22), 10527-10532. -
NLM
Oliveira DM, Freitas HS de, Souza MFF, Arçari DP, Ribeiro ML, Carvalho P de O, Bastos DHM. Yerba Maté (Ilex paraguariensis) aqueous extract decreases intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic wistar rats. Journal of Agricultural and Food Chemistry. 2008 ; 56( 22): 10527-10532.[citado 2024 abr. 24 ] -
Vancouver
Oliveira DM, Freitas HS de, Souza MFF, Arçari DP, Ribeiro ML, Carvalho P de O, Bastos DHM. Yerba Maté (Ilex paraguariensis) aqueous extract decreases intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic wistar rats. Journal of Agricultural and Food Chemistry. 2008 ; 56( 22): 10527-10532.[citado 2024 abr. 24 ] - Avaliação da eficácia de treinamento para manipuladores de sanduíche baguncinha nas ruas de Cuiabá/MT
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