Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more (2006)
- Autores:
- Autores USP: LATORRE, MARIA R. D. O. - FSP ; KRIEGER, JOSE EDUARDO - FM
- Unidades: FSP; FM
- DOI: 10.1016/j.ijcard.2005.03.044
- Assuntos: SISTEMA CARDIOVASCULAR (FREQUÊNCIA); PROTEÍNAS; FISIOLOGIA CARDIOVASCULAR
- Idioma: Inglês
- Resumo: Background: To test the hypothesis of an association between cardiac autonomic activity evaluated by heart rate variability and systemic inflammatory markers such as C-reactive protein, we studied the correlation of the indices of heart rate variability relative to serum high-sensitivity C-reactive protein (hs-CRP) in a healthy Brazilian population.Methods: Four hundred twenty-one healthy individuals aged 15-82 years (mean 40.4 years), 184 men (43.7 percent) and 237 women (56.3 percent) were enrolled between July 1998 and July 2001. The relationship between the log-transformed indices of the heart rate variability and the serum concentration of hs-CRP were analyzed stratified by age tertile using the Spearman correlation coefficient and multiple linear regression. Results: The log standard deviation of all normal sinus RR intervals over 24 h (SDNN) (r = - 0.801; p = 0.024) was independently correlated with log hs-CRP in the individuals with age in the oldest tertile (> or = 46 years). In addition, the body mass index (BMI) was independently correlated with hs-CRP in all of the age groups. Conclusions: In the healthy subjects aged 46 years or more the lower heart rate variability correlated with higher concentration of hs-CRP
- Imprenta:
- Fonte:
- Título do periódico: International Journal of Cardiology
- ISSN: 0167-5273
- Volume/Número/Paginação/Ano: v. 107, p. 333-337, 2006
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
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ABNT
ARAÚJO, Fernando et al. Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more. International Journal of Cardiology, v. 107, p. 333-337, 2006Tradução . . Disponível em: https://doi.org/10.1016/j.ijcard.2005.03.044. Acesso em: 19 set. 2024. -
APA
Araújo, F., Antelmi, I., Pereira, A. C., Latorre, M. do R. D. de O., Grupi, C. J., Krieger, J. E., & Mansur, A. J. (2006). Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more. International Journal of Cardiology, 107, 333-337. doi:10.1016/j.ijcard.2005.03.044 -
NLM
Araújo F, Antelmi I, Pereira AC, Latorre M do RD de O, Grupi CJ, Krieger JE, Mansur AJ. Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more [Internet]. International Journal of Cardiology. 2006 ; 107 333-337.[citado 2024 set. 19 ] Available from: https://doi.org/10.1016/j.ijcard.2005.03.044 -
Vancouver
Araújo F, Antelmi I, Pereira AC, Latorre M do RD de O, Grupi CJ, Krieger JE, Mansur AJ. Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more [Internet]. International Journal of Cardiology. 2006 ; 107 333-337.[citado 2024 set. 19 ] Available from: https://doi.org/10.1016/j.ijcard.2005.03.044 - The influence of tumor necrosis factor -308 and C-reactive protein G1059C gene variants on serum concentration of C-reactive protein: evidence for an age-dependent association
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Informações sobre o DOI: 10.1016/j.ijcard.2005.03.044 (Fonte: oaDOI API)
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