Distribution of hyaluronan and versican in mice embryos during organogenesis (2004)
- Authors:
- Autor USP: ZORN, TELMA MARIA TENORIO - ICB
- Unidade: ICB
- Assunto: HISTOLOGIA
- Language: Inglês
- Abstract: Embryonic development is a complex process that constitutes an excellent model for the study of extracellular matrix (ECM) molecules. Considering the biological characteristics of glycosaminoglycans and proteoglycans we may expect that they play a role during embryonic organogenesis. Hyaluronan (HA) is important as space filler during embryonic development. HA also participate in chemical signaling between cells. Versican (VER) regulates the cell survival, proliferation and migration and participates in the structural reorganization of ECM molecules, necessary for the development and maintenance of the tissues during embryonic development. This work shows the distribution of AH and VER in embryonic tissue of mice from E9 to E15 stages. Embryos on E9 to E15 stages of the development were fixed in Methacarn. HA and VER was localized by immunocytochemistry using specific antibodies. Both HA and VER were present in embryonic tissues in all developmental stages. HA was distributed in the extracellular spaces of connective tissues whereas VER was present around connective tissue cells and epithelial cells. Both molecules were present in the epithelial/mesenchymal interface. Both HA and VER are expressed in the connective and epithelial interface suggesting that these molecules play a role in the establishment of epithelial/mesenchymal interactions. The presence of these molecules in the early stages of the embryonic development indicates that bothparticipate in the morphogenesis and organogenesis of mice
- Imprenta:
- Source:
- Título do periódico: Abstracts
- Conference titles: Congress of the Brazilian Society for Cell Biology
-
ABNT
MIQUELOTO, Carlos Alberto e ZORN, Telma Maria Tenório. Distribution of hyaluronan and versican in mice embryos during organogenesis. 2004, Anais.. Campinas: Instituto de Ciências Biomédicas, Universidade de São Paulo, 2004. . Acesso em: 23 abr. 2024. -
APA
Miqueloto, C. A., & Zorn, T. M. T. (2004). Distribution of hyaluronan and versican in mice embryos during organogenesis. In Abstracts. Campinas: Instituto de Ciências Biomédicas, Universidade de São Paulo. -
NLM
Miqueloto CA, Zorn TMT. Distribution of hyaluronan and versican in mice embryos during organogenesis. Abstracts. 2004 ;[citado 2024 abr. 23 ] -
Vancouver
Miqueloto CA, Zorn TMT. Distribution of hyaluronan and versican in mice embryos during organogenesis. Abstracts. 2004 ;[citado 2024 abr. 23 ] - Sites of 3H-estradiol binding on uterine tissues in pseudopregnant mice
- A graduação valorizada[Depoimento]
- Localização de 3H-estradiol em tecidos uterinos de camundongos pseudográvidos: estudo radiautográficos
- Endometrium of mouse during pre-implantation period: morphological and immunohistochemical study
- Expressão de versican e ácido hialurônico nos tecidos uterinos durante o período de peri-implantação
- Versican and hyaluronan expression in the mouse uterus during the peri-implantation period
- Decidualization in rodents. the role of the small leucin-rich proteoglycans in the collagen fibrillogenesis
- Expression and space-time distribution of PRLd in the mouse endometrium during the firsthalf of pregnancy
- Distribution of extracellular matrix during inner ear morphogenesis
- Space-time relationship and distribution of collagen types I, III and IV in the embryologic development of the inner, middle and external ear
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas