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Artigo de periodico
Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia (2023)
Lima, Keli Cristina de ; Carvalho, Maria Fernanda Lopes ; Martins, Diego Antonio Pereira ; Silva, Wellington Fernandes da; Nascimento, Mariane Cristina do ; Miranda, Lívia Bassani Lins De ; Medeiros, Rita de Cássia Cavaglieri ; Nardinelli, Luciana; Leal, Aline de Medeiros; Velloso, Elvira Deolinda Rodrigues Pereira ; Bendit, Israel ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: FM, ICB, FMRP
Subjects: HEMATOLOGIA, LEUCEMIA, LINFOMA, DOENÇAS SANGUÍNEAS E LINFÁTICAS, INIBIDORES QUÍMICOS, ESTUDOS DE COORTES, EXPRESSÃO GÊNICA, REAÇÃO EM CADEIA POR POLIMERASE, WESTERN BLOTTING, CITOMETRIA DE FLUXO, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
LIMA, Keli Cristina de et al. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia. Blood, v. 142, p. 5886, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-189786. Acesso em: 03 jun. 2024.
APA
Lima, K. C. de, Carvalho, M. F. L., Martins, D. A. P., Silva, W. F. da, Nascimento, M. C. do, Miranda, L. B. L. D., et al. (2023). Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia. Blood, 142, 5886. doi:10.1182/blood-2023-189786
NLM
Lima KC de, Carvalho MFL, Martins DAP, Silva WF da, Nascimento MC do, Miranda LBLD, Medeiros R de CC, Nardinelli L, Leal A de M, Velloso EDRP, Bendit I, Schuringa JJ, Rego EM, Machado Neto JA. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia [Internet]. Blood. 2023 ; 142 5886.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189786
Vancouver
Lima KC de, Carvalho MFL, Martins DAP, Silva WF da, Nascimento MC do, Miranda LBLD, Medeiros R de CC, Nardinelli L, Leal A de M, Velloso EDRP, Bendit I, Schuringa JJ, Rego EM, Machado Neto JA. Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia [Internet]. Blood. 2023 ; 142 5886.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189786
Artigo de periodico
Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors (2023)
Melo, Manuela Albuquerque de ; Macedo, Brunno Gilberto Santos ; Fonseca, Natasha Peixoto ; Scheucher, Priscila Santos ; Martins, Diego Antonio Pereira ; Traina, Fabiola ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: FMRP, ICB
Subjects: FARMACOLOGIA, HEMATOLOGIA, CÉLULAS MIELOIDES, LEUCEMIA MIELOIDE AGUDA, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
MELO, Manuela Albuquerque de et al. Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors. Blood, v. 142, n. Supl. 1, p. 5752, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-190724. Acesso em: 03 jun. 2024.
APA
Melo, M. A. de, Macedo, B. G. S., Fonseca, N. P., Scheucher, P. S., Martins, D. A. P., Traina, F., & Machado Neto, J. A. (2023). Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors. Blood, 142( Supl. 1), 5752. doi:10.1182/blood-2023-190724
NLM
Melo MA de, Macedo BGS, Fonseca NP, Scheucher PS, Martins DAP, Traina F, Machado Neto JA. Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors [Internet]. Blood. 2023 ; 142( Supl. 1): 5752.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-190724
Vancouver
Melo MA de, Macedo BGS, Fonseca NP, Scheucher PS, Martins DAP, Traina F, Machado Neto JA. Autophagy induction constitutes a targetable vulnerability in FLT3-mutant acute Myeloid Leukemia cells treated with FLT3-inhibitors [Internet]. Blood. 2023 ; 142( Supl. 1): 5752.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-190724
Artigo de periodico
Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia (2023)
Lima, Keli Cristina de ; Carvalho, Maria Fernanda Lopes ; Martins, Diego Antonio Pereira ; Nascimento, Mariane Cristina do ; Nogueira, Frederico Lisboa ; Medeiros, Rita de Cássia Cavaglieri ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: FM, ICB, FMRP
Subjects: FARMACOLOGIA, HEMATOLOGIA, LEUCEMIA MIELOIDE AGUDA, QUIMIOTERAPIA COMBINADA, CÉLULAS CULTIVADAS DE TUMOR, PROLIFERAÇÃO CELULAR, NEOPLASIAS POR TIPO HISTOLÓGICO, ANTINEOPLÁSICOS, PROTEÍNAS, CÉLULAS MIELOIDES
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
LIMA, Keli Cristina de et al. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia. Blood, v. 142, n. Supl. 1, p. 5774, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-189998. Acesso em: 03 jun. 2024.
APA
Lima, K. C. de, Carvalho, M. F. L., Martins, D. A. P., Nascimento, M. C. do, Nogueira, F. L., Medeiros, R. de C. C., et al. (2023). Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia. Blood, 142( Supl. 1), 5774. doi:10.1182/blood-2023-189998
NLM
Lima KC de, Carvalho MFL, Martins DAP, Nascimento MC do, Nogueira FL, Medeiros R de CC, Schuringa JJ, Rego EM, Machado Neto JA. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia [Internet]. Blood. 2023 ; 142( Supl. 1): 5774.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189998
Vancouver
Lima KC de, Carvalho MFL, Martins DAP, Nascimento MC do, Nogueira FL, Medeiros R de CC, Schuringa JJ, Rego EM, Machado Neto JA. Identification of vulnerabilities for pharmacological inhibition of PIP4K2s in Acute Myeloid Leukemia [Internet]. Blood. 2023 ; 142( Supl. 1): 5774.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189998
Artigo de periodico
Cephalochromin-induced mitochondrial damage overcomes venetoclax-resistance in acute Myeloid Leukemia Models (2023)
Nascimento, Mariane Cristina do ; Martins, Diego Antonio Pereira ; Alcântara, Guilherme Augusto Sousa; Lima, Keli Cristina de ; Vicari, Hugo Passos ; Huls, Gerwin A. ; Schuringa, Jan Jacob ; Rego, Eduardo Magalhães ; Ferreira, Marcelo José Pena ; Costa-Lotufo, Leticia Veras ; Machado Neto, João Agostinho
Source: Blood. Conference titles: 65th ASH Annual Meeting Abstracts. Unidades: IB, FM, ICB, FMRP
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, HEMATOLOGIA, QUIMIOTERAPIA COMBINADA, CÉLULAS CULTIVADAS DE TUMOR, PROLIFERAÇÃO CELULAR, NEOPLASIAS POR TIPO HISTOLÓGICO, APOPTOSE, DANO AO DNA, MITOCÔNDRIAS, PROTEÔMICA, ANTINEOPLÁSICOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
NASCIMENTO, Mariane Cristina do et al. Cephalochromin-induced mitochondrial damage overcomes venetoclax-resistance in acute Myeloid Leukemia Models. Blood, v. 142, n. res. 604, p. 5751, 2023Tradução . . Disponível em: https://doi.org/10.1182/blood-2023-189814. Acesso em: 03 jun. 2024.
APA
Nascimento, M. C. do, Martins, D. A. P., Alcântara, G. A. S., Lima, K. C. de, Vicari, H. P., Huls, G. A., et al. (2023). Cephalochromin-induced mitochondrial damage overcomes venetoclax-resistance in acute Myeloid Leukemia Models. Blood, 142( res. 604), 5751. doi:10.1182/blood-2023-189814
NLM
Nascimento MC do, Martins DAP, Alcântara GAS, Lima KC de, Vicari HP, Huls GA, Schuringa JJ, Rego EM, Ferreira MJP, Costa-Lotufo LV, Machado Neto JA. Cephalochromin-induced mitochondrial damage overcomes venetoclax-resistance in acute Myeloid Leukemia Models [Internet]. Blood. 2023 ; 142( res. 604): 5751.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189814
Vancouver
Nascimento MC do, Martins DAP, Alcântara GAS, Lima KC de, Vicari HP, Huls GA, Schuringa JJ, Rego EM, Ferreira MJP, Costa-Lotufo LV, Machado Neto JA. Cephalochromin-induced mitochondrial damage overcomes venetoclax-resistance in acute Myeloid Leukemia Models [Internet]. Blood. 2023 ; 142( res. 604): 5751.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2023-189814
Artigo de periodico
Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia (2022)
Lima, Keli ; Pereira-Martins Diego A. ; Miranda, Lívia Bassani Lins de ; Coelho-Silva, Juan L. ; Leandro, Giovana da Silva ; Isabel Weinhäuser ; Cavaglieri, Rita de Cássia ; Silva, Wellington F.; Leal, Aline Medeiros; Lange, Ana Paula Alencar de Lima; Velloso, Elvira Deolinda Rodrigues Pereira ; Griessinger, Emmanuel ; Hilberink, Jacobien R. ; Huls, Gerwin A. ; Schuringa, Jan Jacob ; Rego, Eduardo M. ; Machado Neto, João Agostinho
Source: Blood. Unidades: FM, ICB, FMRP
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, NEOPLASIAS POR TIPO HISTOLÓGICO, AMINOÁCIDOS, PROTEÍNAS QUINASES, DANO AO DNA, MITOCÔNDRIAS, HOMEOSTASE, LISOSSOMOS
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
LIMA, Keli et al. Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia. Blood, v. 140, p. 5965–5966, 2022Tradução . . Disponível em: https://doi.org/10.1182/blood-2022-165172. Acesso em: 03 jun. 2024.
APA
Lima, K., Pereira-Martins Diego A.,, Miranda, L. B. L. de, Coelho-Silva, J. L., Leandro, G. da S., Isabel Weinhäuser,, et al. (2022). Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia. Blood, 140, 5965–5966. doi:10.1182/blood-2022-165172
NLM
Lima K, Pereira-Martins Diego A., Miranda LBL de, Coelho-Silva JL, Leandro G da S, Isabel Weinhäuser, Cavaglieri R de C, Silva WF, Leal AM, Lange APA de L, Velloso EDRP, Griessinger E, Hilberink JR, Huls GA, Schuringa JJ, Rego EM, Machado Neto JA. Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia [Internet]. Blood. 2022 ; 140 5965–5966.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2022-165172
Vancouver
Lima K, Pereira-Martins Diego A., Miranda LBL de, Coelho-Silva JL, Leandro G da S, Isabel Weinhäuser, Cavaglieri R de C, Silva WF, Leal AM, Lange APA de L, Velloso EDRP, Griessinger E, Hilberink JR, Huls GA, Schuringa JJ, Rego EM, Machado Neto JA. Targeting PIP4K2 lipid kinases through Thz-P1-2 reveals vulnerabilities related to mitochondrial homeostasis and autophagy in acute leukemia [Internet]. Blood. 2022 ; 140 5965–5966.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1182/blood-2022-165172
Artigo de periodico
The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy (2022)
Lima, Keli Cristina de ; Martins, Diego Antonio Pereira ; Miranda, Lívia Bassani Lins De ; Silva, Juan Luiz Coelho ; Leandro, Giovana da Silva ; Weinhäuser, Isabel ; Cavaglieri, Rita de Cássia; Leal, Aline de Medeiros; Silva, Wellington Fernandes da; Lange, Ana Paula Alencar de Lima; Velloso, Elvira Deolinda Rodrigues Pereira ; Rego, Eduardo Magalhães ; Griessinger, Emmanuel ; Hilberink, Jacobien R. ; Ammatuna, Emanuele ; Huls, Gerwin ; Schuringa, Jan Jacob ; Machado Neto, João Agostinho
Source: Blood Cancer Journal. Unidades: FM, ICB, FMRP
Subjects: FARMACOLOGIA, LEUCEMIA MIELOIDE AGUDA, HOMEOSTASE, APOPTOSE, MITOCÔNDRIAS, ESPECTROMETRIA DE MASSAS, CROMATOGRAFIA LÍQUIDA, CÉLULAS-TRONCO
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
ABNT
LIMA, Keli Cristina de et al. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy. Blood Cancer Journal, v. 12, p. 1-11, 2022Tradução . . Disponível em: https://doi.org/10.1038/s41408-022-00747-w. Acesso em: 03 jun. 2024.
APA
Lima, K. C. de, Martins, D. A. P., Miranda, L. B. L. D., Silva, J. L. C., Leandro, G. da S., Weinhäuser, I., et al. (2022). The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy. Blood Cancer Journal, 12, 1-11. doi:10.1038/s41408-022-00747-w
NLM
Lima KC de, Martins DAP, Miranda LBLD, Silva JLC, Leandro G da S, Weinhäuser I, Cavaglieri R de C, Leal A de M, Silva WF da, Lange APA de L, Velloso EDRP, Rego EM, Griessinger E, Hilberink JR, Ammatuna E, Huls G, Schuringa JJ, Machado Neto JA. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy [Internet]. Blood Cancer Journal. 2022 ; 12 1-11.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1038/s41408-022-00747-w
Vancouver
Lima KC de, Martins DAP, Miranda LBLD, Silva JLC, Leandro G da S, Weinhäuser I, Cavaglieri R de C, Leal A de M, Silva WF da, Lange APA de L, Velloso EDRP, Rego EM, Griessinger E, Hilberink JR, Ammatuna E, Huls G, Schuringa JJ, Machado Neto JA. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy [Internet]. Blood Cancer Journal. 2022 ; 12 1-11.[citado 2024 jun. 03 ] Available from: https://doi.org/10.1038/s41408-022-00747-w

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